Cell biology: Cytoplasmic rivers carry molecular cargo: Current Biology www.cell.com/current-biol...
Cell biology: Cytoplasmic rivers carry molecular cargo
Molecules in the cytoplasm of an animal cell move by diffusion, motor activity, and/or fluid flow. A recent study demonstrates how directed, but often subtle, cytoplasmic drift currents carry cytoskel...
cell.com
So grateful to @mullinslab.bsky.social for the kind write-up. And I'm lucky to have chased this from so many technical angles with @cathygalbraith.bsky.social, @jimgalbraith27.bsky.social & @ulrikeboehm.bsky.social.
@focalplane.bsky.social asked us for the behind the paper story on uncovering Compartmentalized Cytoplasmic Tradewinds. Read about it here. (along with a new YouTube video) A great collaboration with @sciencethecat.bsky.social and @ulrikeboehm.bsky.social focalplane.biologists.com/2026/07/09/c...
Cytoplasmic Tradewinds: How Cells Steer Proteins
Six imaging methods reveal cytoplasmic tradewinds: a hidden fluid flow that pushes soluble proteins using a leaky actin-myosin barrier.
focalplane.biologists.com
It all started with (#2 in the series) New in Nature Methods - spontaneously blinking dyes for live cell super-resolution. No harsh chemicals or damaging light. 2 Nature family papers in two weeks 🤯 @rhodamine110.bsky.social @sciencethecat.bsky.social doi.org/10.1038/s415... doi.org/10.1038/s414...
Just out: A series of spontaneously blinking dyes for super-resolution microscopy with @rhodamine110.bsky.social and an incredible team of collaborators. www.nature.com/articles/s41... It's been an amazing few weeks -- this follows our cytoplasmic tradewinds paper. www.nature.com/articles/s41...
Out in @natmethods.nature.com: More dyes. They work. Quite well. And blink. Pick the one that fits your target, your technique, and your labeling density. With too many collaborators and institutes to list, but anchored at @hhmijanelia.bsky.social www.nature.com/articles/s41...
A series of spontaneously blinking dyes for super-resolution microscopy - Nature Methods
A series of spontaneously blinking dyes in the far-red range facilitate single-molecule localization microscopy. These dyes vary in their blinking properties and can be matched to the applications and...
nature.com
Some great (but not surprising to me) news! "The Trump administration will not be asking the Supreme Court to take up its fight to slash federal support for funding that the nation’s science enterprise relies on for basic operating costs." www.statnews.com/2026/04/08/t... 1/2
Trump administration drops court fight to cap NIH payments for research overhead costs
The Trump administration will not be asking the Supreme Court to take up its fight to slash NIH support for research indirect costs
statnews.com
DEADLINE EXTENDED! ⏰ Apply to Optical Microscopy & Imaging in the Biomedical Sciences (OMIBS) by April 8. Click the link in the bio for more info.
How do proteins find their way to the cell's leading edge? @jimgalbraith27.bsky.social & @cathygalbraith.bsky.social break down how bleach line, FLOP, single-particle tracking, FCS & iPALM reveal intracellular fluid flow and an actin-myosin compartment barrier. doi.org/10.1038/s414...