Lola Solebo
@lolaeyedoc.bsky.social
Academic / Paediatric Ophthalmologist Epidemiology, Eyes/Vision, Imaging, Data science, Health equity. Huge nerd. Not necessarily in that order. Both kinds of doctor. https://www.ted.com/talks/dr_lola_solebo_through_the_eyes_of_a_child?subtitle=en
The first CHOIR Community webinar takes place tonight at 7pm BST 🎉 This is a new space for children, young people & families affected by rare childhood-onset inflammatory eye conditions. Register: ucl.zoom.us/webinar/regi... choir-lab.com #CHOIR #Uveitis #Ophthalmology @lolaeyedoc.bsky.social
Researchers from UCL and Moorfields Eye Hospital NHS have made a significant contribution to our understanding of uveitis and recently shared their findings in Nature Communications. Read about the study here: https://ow.ly/8HOX50YbK62 #Research #Uveitis #MedicalResearch
📢 Childhood Onset Uveitis Info Day (UNICORNS Group) 🦄 📅 Sun 5 Oct 2025 | ⏰ 10:00–16:00 BST 📍 Weston House, Great Ormond St, London + Online Join for expert talks & support on childhood #uveitis @lolaeyedoc.bsky.social Unicorns: www.ucl.ac.uk/population-h... www.eventbrite.com/e/childhood-...
UNICORNS
Uveitis in childhood prospective national cohort study
ucl.ac.uk
A rose by any other name might smell as sweet but would get misclassified: Nomenclature for AS OCT url:https://jamanetwork.com/journals/jamaophthalmology/fullarticle/2837462?utm_source=bluesky&utm_campaign=content-shareicons&utm_content=article_engagement&utm_medium=social&utm_term=081825
So great to see ARR collaborators in science translational medicine this morning - www.science.org/doi/10.1126/.... An important movement for #Paed Rheum research and tissue biology #immunosky @dr-chrissyb.bsky.social #Wedderburngroup #Croftgroup #ChrisMahony @science.org
Synovial tissue atlas in juvenile idiopathic arthritis reveals pathogenic niches associated with disease severity
An atlas of the cellular and molecular landscape of the juvenile idiopathic arthritis synovium defines tissue niches associated with disease severity.
science.org
Researchers at @ucl.ac.uk's Great Ormond Street Institute for Child Health and @greatormondst.bsky.social including Professor Lucy Wedderburn have identified a set of genes which could help predict children's response to an arthritis treatment @uclpophealthsci.bsky.social
Genes may help to predict which children will respond well to arthritis treatment
A set of genes that could be used to help doctors predict which children will respond well to treatment for juvenile idiopathic arthritis (JIA) have been identified by researchers at UCL and Great Orm...
ucl.ac.uk
We’re accepting applications for our Accelerator Awards. This opportunity aims to support researchers of Black, Bangladeshi and Pakistani heritage in the UK to undertake activities that help them build a stronger profile to make successful career transitions within academia. Find out more ⤵️
Accelerator Awards | Grant funding | Wellcome
Eligibility and applications details for the Wellcome Accelerator Awards, which will support Black, Bangladeshi, and Pakistani researchers in the UK to make successful career transitions.
wellcome.org
Inflammatory cell or pigment? Sometimes hard to tell on a slit lamp, even for an expert clinician, and there aren’t many of those to go round. AS-OCT appears to rise to the challenge: 🧪 www.nature.com/articles/s41...
Article Metrics - Differentiation of anterior chamber pigment and inflammatory cells using swept-source optical coherence tomography: a cross-sectional study | Eye
nature.com
Delighted to be included in this great initiative highlighting researchers in our new departments located in @uclmedsci.bsky.social. Can’t wait to read @georgearobinson.bsky.social next week!
UCL Dept of Aging, Rheumatology & Regenerative Medicine@arrdept-ucldom.bsky.social · last yr.To celebrate having over 300 followers 👋 it’s time for our first PI researcher spotlight @bcellsrosser.bsky.social. Dr Lizzy Rosser established her group in 2022 which focuses on understanding what causes B cells to misbehave in childhood and adolescent onset autoimmune diseases 🦠
It seems PubMed has disappeared. This is the digital equivalent of burning a library.
If someone thinks the measles outbreak and childhood death in Texas are "not unusual" or "happens all the time", they are deeply misinformed. h/t @adamratnermd.bsky.social for the inspiration. blogs.jwatch.org/hiv-id-obser...
Tragic Childhood Death from Measles Reminds Us That Some Don't Understand Either the Medical Significance or the Human Heart
My ID colleague Dr. Adam Ratner, Chief of Pediatric ID at NYU Medical Center, just published an insightful and remarkably timely book called Booster Shots: The Urgent Lessons of Measles and the Uncer...
blogs.jwatch.org
NEW JOB ALERT 📢 Want to come and 🌠SHINE as a new member of the UCL Child Health Vision and Eyes Group? We are looking for an Epidemiologist / Data Scientist 🧪 to join the team - advert below www.ucl.ac.uk/work-at-ucl/...
UCL – University College London
UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).
ucl.ac.uk
The ADJUST trial is out! Q: what is the chance of JIA uveitis recurrence after stopping Adalimumab? A: Pretty high - so counsel children and parents carefully when starting 🧪👁️ www.the Lancet.com/journals/lancet/article/PIIS0140-6736(24)02468-1/fulltext
Stopping of adalimumab in juvenile idiopathic arthritis-associated uveitis (ADJUST): a multicentre, double-masked, randomised controlled trial
Discontinuing adalimumab led to higher rates of recurrence of uveitis, arthritis, or both in patients with previously controlled juvenile idiopathic arthritis-associated uveitis. However, all patients...
thelancet.com
Funded by a @wellcometrust.bsky.social grant, we will be growing our CHOIR team - making discoveries which deepen our understanding of childhood ocular inflammatory disease. 2025 will bring us two new post docs, and a pre-doc (with funding available for a studentship) - keep a look out!
My peak* Reflecting on goals for 2025 and nothing really comes close Happy New Year! *a backwards roly-poly was needed, I think. No, no, hold your applause - the award was award enough
“Equitable, Diverse & Inclusive Ophthalmology through the Eyes of a Geordie Ghanaian” FULL recording of my Presidential Address for RSM Ophthalmology is FREE to watch. A raw account of navigating systemic racism, anti-Blackness & misogynoir. Love & light Evie 💖✨ www.rsm.ac.uk/sections/oph...
Ophthalmology Section | The Royal Society of Medicine
The RSM Ophthalmology Section’s purpose is to promote and provide accredited educational study of best practice in the field of ophthalmology.
rsm.ac.uk
I’m also the product of Star Trek, Sesame Street, and Muppet Movies. I think we can do anything with hard work, dreaming just a little bigger and maybe singing along the way.
Well presented case from Tufts with some useful OCT images:
Ophthopedia @ophthalmology.bsky.social · 2y agoOphthopedia Update: Young adult presents with blurry vision: A 24-year-old previously healthy Greek man with recent COVID-19 infection presented to the Tufts emergency department with a 1-week history of high fevers, generalized weakness, sore throat and blurry… #ophthalmology #eye #eyenews
Children and their families told us that they wanted more uveitis research - and we listened (www.ucl.ac.uk/child-health...) We are looking forward to hearing your voices again. Link is here and in the image: redcap.link/churp
One of my biggest joys is seeing an entire community take a stand for something important. STANDING Together, recommendations for health data diversity and algorithmic bias is now published: an international effort involving >350 experts & 58 countries. www.thelancet.com/journals/lan...
Tackling algorithmic bias and promoting transparency in health datasets: the STANDING Together consensus recommendations
Without careful dissection of the ways in which biases can be encoded into artificial intelligence (AI) health technologies, there is a risk of perpetuating existing health inequalities at scale. One major source of bias is the data that underpins such technologies. The STANDING Together recommendations aim to encourage transparency regarding limitations of health datasets and proactive evaluation of their effect across population groups. Draft recommendation items were informed by a systematic review and stakeholder survey.
thelancet.com
I can hardly think of a better example of the moral decay in modern health care than a Goldman analyst noting that biotech cures for diseases like hepatitis are cool and all, until their success diminishes the business opportunity for pharmaceutical manufacturers. www.cnbc.com/2018/04/11/g...
Goldman Sachs asks in biotech research report: 'Is curing patients a sustainable business model?'
Goldman Sachs warns sales from the most successful disease treatments are difficult to maintain.
cnbc.com
Interesting article from the #ClevelandEye Pichi / Neri team suggesting that body weight is linked to how well humira (also called Amgevita / Adalimumab) works in childhood uveitis. Could we start using BMI to adjust for humira dosing to reduce the chance of developing anti-drug antibodies?🧪👁️
Ophthopedia @ophthalmology.bsky.social · 2y agoOphthopedia Update: IMPACT OF BMI ON ADALIMUMAB EFFICACY IN PEDIATRIC JIA-ASSOCIATED UVEITIS: Chronic anterior uveitis (CAU) is the most common type of pediatric uveitis, frequently associated with juvenile idiopathic arthritis (JIA). The introduction of… #Ophthalmology #ophthotwitter #eyecare
Extra-musculoskeletal manifestations are an important treatment consideration for patients with spondyloarthritis. In this analysis, development of uveitis, IBD, and psoriasis was generally low with upadacitinib 15 mg, incl. numerically lower rates of uveitis vs placebo A&R doi.org/10.1002/art....
We need transformational changes to address the worrying decline in children’s health and wellbeing - AcMedSci is showing welcome, much needed leadership on this:
Academy of Medical Sciences@acmedsci.bsky.social · 2y ago"We lack the imagination to relieve children's suffering" - Prof Helen Minnis FMedSci in The Big Issue. Govt should prioritise young children in healthcare & education Minnis argues, calling for a reallocation of resources to support child development. Read more 👇 bit.ly/3XyUYi1 #ThriveByFive
"We lack the imagination to relieve children's suffering" - Prof Helen Minnis FMedSci in The Big Issue. Govt should prioritise young children in healthcare & education Minnis argues, calling for a reallocation of resources to support child development. Read more 👇 bit.ly/3XyUYi1 #ThriveByFive
Why the natural human failure of imagination stops us from relieving children's suffering
To fix the problems of society, we must begin by reimagining our priorities and putting our babies and children first.
bit.ly
People who use statistical modelling studies which *assume* efficacy as if they are *evidence* of efficacy, have either not read the research, don’t understand the research, or worse - are wilfully misusing the research Models should not be used as propaganda
Against Models as Propaganda
We examine the misuse of infectious disease models as ideological tools
open.substack.com
The democratisation of expertise (augmentation of decision making, an 82% reduction in infant mortality) described in this article really is the great promise of medical AI. Underserved populations are likely to be most damaged by implementation gone wrong - but they also have the most to gain.
The Guardian@theguardian.com · 2y agoHow AI monitoring is cutting stillbirths and neonatal deaths in a clinic in Malawi
Seems that 4 monitors is not enough... Jason and Shangbang are choosing which cone on my retina to perform #AOOCT and #AOSLO #optoretinography measurements.
