Macrophage-derived oxysterols recruit GPR183+ TH2 cells into fungal lesions, suppressing type 1 immunity and promoting pathogen persistence @sciimmunology.bsky.social www.science.org/doi/10.1126/...
Lizzy Rosser
@bcellsrosser.bsky.social
Interested in all things B cells, autoimmunity, nutritional immunology and child health. Located at UCL. Immunometabolism Section Editor for Clinical and Experimental Immunology. Check out our lab website - rosserlab.com
A ketogenic diet promotes tumour growth in the small intestine in susceptible mice go.nature.com/3TB3Cge
A high-fat, low-carbohydrate diet can feed intestinal tumours
A ketogenic diet promotes tumour growth in the small intestine in susceptible mice. In people, diet advice might need to be tailored to individual cancer risks.
go.nature.com
@jem.org a new type I IFN–dependent psoriasis subtype resulting from rare heterozygous variants in ADAR1 and associated with a specific response to JAK1 and TYK2 inhibitors @inserm.fr rupress.org/jem/article-...
Not only will I be presenting some data we’ve never taken out ‘in the wild’ before. But it’s gonna be a great meeting!
British Society for Immunology@britsocimm.bsky.social · 4w ago⌛️ 5 days to go! Submit your abstract for our event with @london-immuno.bsky.social here: vist.ly/59p7t
Just updated our website and the new Immunometabolism section in @britsocimm.bsky.social’s Clinical and Experimental Immunology journal and my role as section editor - rosserlab.com/news--events check it out!
News & Events
rosserlab.com
Reversible suppression of autophagy in a mouse model reveals neuronal resilience @science.org www.science.org/doi/10.1126/...
Woo!
British Society for Immunology@britsocimm.bsky.social · last mo.🚀 Excited to announce the Immunometabolism Section in @ceijournal.bsky.social led by Dr Lizzy Rosser (UCL) A dedicated home for cutting-edge research exploring how metabolism shapes immune function in health and disease. Learn more: vist.ly/58wxd #Immunometabolism #Immunology
Very excited to be announced as the new section editor for the brand new ‘immunometabolism’ section in @britsocimm.bsky.social journal Clinical and Experimental Immunology… find out more below 👇 and please keep us in mind for your new Immunometabolism stories 🗞️ www.immunology.org/news/clinica...
Clinical & Experimental Immunology launches new Immunometabolism section | British Society for Immunology
immunology.org
Had an absolutely amazing couple of days in Dublin with @thelisterinstitute.bsky.social making new friends, talking about the transformative impact the Lister prize has had on my career, and forging new connections with the Irish scientific community. I’m so excited to see what comes of this trip…!
The Lister Institute of Preventive Medicine@thelisterinstitute.bsky.social · 2mo agoSpecial thanks to current #ListerFellows @chillzaa.bsky.social @bcellsrosser.bsky.social @tjryan.bsky.social and former Fellows @corrigar.bsky.social and @agagambus.bsky.social for talking about the real impact that our flexible Prize funding makes to research careers and pursuing bold ideas!
🚨 New Publication Alert - out now in @science.org - We outline the environmental regulators of MAIT cells including the nutrients they need - with them coming into focus in cancer this is sure to be important - read it here doi.org/10.1126/scis...
Environmental regulation of mucosal-associated invariant T cells: Adding food for thought
Nutrients are important environmental factors that affect the functional responses of MAIT cells to challenge.
doi.org
Great to see Nick in action at the #EASLCongress this year, presenting his work on the gut-liver axis in PSC! Nick’s abstract was also featured in the best at EASL showcase, titled “Microbially deconjugated bile acid-mediated ileal barrier function deficit”👏👨🔬🎉 @kiroxford.bsky.social
Poor supervision is pushing young researchers out of academia www.nature.com/articles/d41...
Poor supervision is pushing young researchers out of academia
A survey finds that academic supervisors can have a huge impact on their students’ mental health.
nature.com
Belimumab combined with conventional therapy enhances NK cell counts, improves serological and clinical outcomes, and facilitates steroid tapering in childhood-onset SLE link.springer.com/article/10.1...
I would love to see treatment-resistant JIA and Uveitis in a study like this one day.
Immunity@cp-immunity.bsky.social · 3mo ago
Join us next Tuesday (May 19, 11am ET) for the Colton Consortium Virtual Seminar featuring Montserrat Anguera, PhD (Penn Vet) who will be covering "Sex Differences in Autoimmune Disease: Xist RNA-Mediated Mechanisms That Influence B Cell Function." Registration required: https://bit.ly/4wwhLdP
Colton Virtual Seminar Series
events.zoom.us
Join us in London this September to explore how environmental signals shape immune responses, with speakers including Yasmine Belkaid, Petter Brodin and more. 📅 Abstract deadline: Monday 29 June 2026 🎟️ Register early to save! Learn more: vist.ly/54ad6
In a lupus-humanized NSG mouse model, an estrogen receptor β (ERβ) agonist, OSU-ERβ-012, inhibited lupus pericarditis and myocarditis phenotypes and reduced systemic proinflammatory cytokine response and inflammatory renal phenotype ACR Open Rheumatology doi.org/10.1002/acr2...
Former #ListerFellow @dandavis101.bsky.social talks about "nanoscale immunity". Check out the story in @wired.com magazine. www.wired.com/story/daniel...
Scientists Are Starting to Unlock the Nanoscale Secrets of the Immune System
At WIRED Health, immunologist Daniel Davis detailed the ways in which new technologies are enabling a better understanding of the human immune system.
wired.com
Boosting the anti-cancer activity of human MAIT cells by getting them to use lactate & directing them using bi-specific engagers @ardeena-berisha.bsky.social @andyhogan82.bsky.social @jimmunol.bsky.social academic.oup.com/jimmunol/art... @maynoothuniversity.ie
Andy Hogan@andyhogan82.bsky.social · 3mo agoDelighted to share our latest paper out today - led by @ardeena-berisha.bsky.social - we show that we can boost the anti-cancer activity of human MAIT cells by getting them to use lactate & also directing them using bi-specific engagers as a proof of concept academic.oup.com/jimmunol/art...
Delighted to share our latest paper out today - led by @ardeena-berisha.bsky.social - we show that we can boost the anti-cancer activity of human MAIT cells by getting them to use lactate & also directing them using bi-specific engagers as a proof of concept academic.oup.com/jimmunol/art...
Lactate conditioning reprograms mucosal-associated invariant T cell metabolism boosting effector function
Abstract. Mucosal-associated invariant T (MAIT) cells are unconventional T cells, which upon activation can display potent cytotoxic and cytokine-producing
academic.oup.com
So great to see a patients perspective in a high-impact review journal.
Nature Reviews Rheumatology@natrevrheum.nature.com · 3mo ago✨ May Issue ✨ | World View What rheumatology can learn from oncology: a patient’s perspective A patient view on how precision diagnostics, meaningful endpoints and biologically grounded classification could transform rheumatic care. 🔗 dlvr.it/TRFLgS #Rheumsky #Medsky
Poor sleep impairs immune responses and influenza vaccine protection @natcomms.nature.com nature.com/articles/s41...
💡1st Adriatic School on Immunometabolism 📍Veli Lošinj, 🇭🇷 🗓️ Oct 18–22, 2026 A new school for early-career scientists exploring immunometabolism. Keynotes, talks, posters & networking with leading international experts in an interactive setting + social program. ℹ️ on registration, program & travel👇
What a conference!! Thank you @britsocimm.bsky.social Immunometabolism affinity group for an amazing 2 days in Newcastle for #UKimmunomet26 - learned so much and met even more amazing people it was the best! 🤩🤓🤩
Sad I missed @dianaematei.bsky.social smashing it at the #BSIimmunometabolism conference bright sparks session… but incredibly happy to be at #EWRR in beautiful Lubeck with the best conference entertainment of all time. The Rosser group seems to be on tour this week!
Gutted to be missing this!
British Society for Immunology@britsocimm.bsky.social · 4mo agoHey #UKimmunomet26 attendees 👋 Come and say hello at the BSI stand! Chat with Laura Franklin (our Journals Manager) and Ellie Pearson (intern at the BSI) about our journals, how to submit your work, and the other opportunities we offer. We’d love to see you there!
A framework to move the promotion and tenure process forward, emphasizing more equitable approaches and outcomes www.science.org/doi/10.1126/...
How does the environment influence immunity? 🌍 Join us on 11 Sept in London for an event with @london-immuno.bsky.social to explore how microbes, diet, pollution & stress affect immune responses in health & disease #LIG26 Register early for a discount! vist.ly/4w2je
Brilliant to hear @uniofexeternews.bsky.social awarded £4.5M from @wellcometrust.bsky.social to develop specialist bioimaging tools for WHO-priority fungal pathogens. Led by #ListerFellow Liz Ballou @balloulab.bsky.social at @mrccmm.bsky.social. Huge congrats, a fastastic achievement 👏
