Pre-print alert 📰 🚨I’m very grateful and excited to share our new study : "Defective B cell tolerance in SLE lymph nodes underpins VH4-34 "clonal damnation" and PD-1+TOX+ autoreactive B cells expansion". doi: doi.org/10.64898/202... lnkd.in/eJwMTUEt
Katia Faliti
@katyely.bsky.social
Immunologist interested in B and T cells in the GC ( and around it) Human SLE, Autoimmunity and Vaccines Currently Instructor at Emory, in the Sanz Lab 🧑🔬💉🔬
'In short, human genetics has become an evolutionary science in a way that can’t be undone. You cannot meaningfully study how humans function or differ from one another without understanding how evolution has shaped us.' www.johnhawks.net/p/what-i-tol...
What I told my students about the threats to evolutionary science
I was floored by the question, but it matters. With U.S. funding crashing, what will happen to the future of the field?
johnhawks.net
Looking forward to #AAI2025 science and connections! #AAI2025 #ImmunoSky
✈️ Don't miss this incredible opportunity! Join us for IMMUNOLOGY2025™ in Honolulu, HI and experience world-class science and island vibes. Early Bird ends tomorrow – register now: immunology2025.aai.org.
#Medsky🧪 #pedsky #immunosky #IDsky #publichealth Children under the age of five have an average incidence of 4 to 6 viral respiratory infections per year, which increases the risk of developing acute bacterial sinusitis or mastoiditis. www.thelancet.com/journals/lan... @thelancetinfdis.bsky.social
Global, regional, and national burden of upper respiratory infections and otitis media, 1990–2021: a systematic analysis from the Global Burden of Disease Study 2021
The findings of this study highlight the widespread burden posed by URIs and otitis media across all age groups and both sexes. There is a continued need for surveillance, prevention, and management t...
thelancet.com
Delighted our study (7+ years in the making) is out today in Nature. In a nutshell, 48 hours of antibiotics in week 1 led to impaired vaccine responses up to 15 months later in infants. We show (in-vivo) a probiotic can fix it #microbiome #science #immunology www.nature.com/articles/s41...
Bifidobacteria support optimal infant vaccine responses - Nature
Neonatal antibiotic use is shown to reduce immune response to infant vaccines, accompanied by reduced abundance of Bifidobacteria in the gut microbiota, with experiments in mice indicating that probio...
nature.com
Letting mice experience the "wild" alters their immune system, especially their B-cells! Also, we talk to an organizer of the Atlanta #standupforscience2025 about his experience 🧪 www.youtube.com/watch?v=7Hgo...
Episode 36 - Mice touching grass
YouTube video by Audiommunity
youtube.com
'The scale of disruption to science funding in the USA is unprecedented. At the NIH, study sections, funding councils and project meetings have been cancelled. Without these, new grants cannot be funded or renewed. Fellowship programs have been cancelled.' journals.biologists.com/dev/article/...
Science under siege: protecting scientific progress in turbulent times
As Editors-in-Chief of The Company of Biologists' journals, we have been watching with growing concern the policy changes in the United States of America (USA) and the challenges that these are creati...
journals.biologists.com
So, not to diminish that this is a good thing but... we still don't know who they'll nominate in his place.
Wowoowowowowowwowowwowowo @defendpublichealth.bsky.social THIS IS A WIN FOR PUBLIC HEALTH!!!!!
‘One last thing’: Trudeau posts message to Canadians on final day as prime minister #Canada #cdnpoli #ThankYouPMTrudeau 🍁💪🏻 www.ctvnews.ca/politics/art...
‘One last thing’: Trudeau posts message to Canadians on final day as prime minister
Prime Minister Justin Trudeau says Canadians are great and shouldn’t change, in a final message posted from his office on his last day in it.
ctvnews.ca
I refuse to accept a post-truth reality where knowledge and humanity no longer matter. Stand up for Science!! #standupforscience
Yeah, this 100%
Graduating during the pandemic slowed down my process and is part of why I did two postdocs. Now as a first year faculty, all the federal grants are frozen. I love the work I do but this has all of us questioning how much www.science.org/content/arti...
Cool paper from the Davis lab using human tonsil organoids to study CD4 and CD8 Tregs. Even though subjects with autoimmunity were excluded, organoids derived from female donors had higher autoreactivity, providing an ex vivo system to study sex differences in response to self antigens. #ImmunoSky 🧪
Differential roles of human CD4+ and CD8+ regulatory T cells in controlling self-reactive immune responses - Nature Immunology
Here the authors use a tonsil organoid culture model system to investigate the roles of human CD4+ and CD8+ regulatory T cells in controlling self-reactive immune responses. CD4+ regulatory T cells we...
nature.com
We have to fight now for research that we know benefits all of humanity, we have to stand up for our colleagues at the NIH, we can’t lie down and take it, we stand against this madness #standupforscience2025
Welcome to the Bluesky account for Stand Up for Science 2025! Keep an eye on this space for updates, event information, and ways to get involved. We can't wait to see everyone #standupforscience2025 on March 7th, both in DC and locations nationwide! #scienceforall #sciencenotsilence
@katherinejwu.com getting straight to the ❤️ of the crisis. This current attack on science must be stopped to protect all Americans.
An absolute must-read from @katherinejwu.com on the rapid destruction of American science: www.theatlantic.com/health/archi...
My weekend with immunologists devising new strategies to treat cancer, allergy, Alzheimer’s, autoimmunity and infection. The WH has just paused peer-reviewed NIH funding that pays for these studies. If you care about human life, write your representatives. Demand that NIH funding is restored asap.
Talk to your department chairs and research offices! 🧪
Per an NIH source: “Discussions with colleagues have suggested that if the universities all come together and raise hell about the delays to funding caused by not holding meetings, that might move the needle. From every state. There are well-funded universities in red states that will be impacted.”
Thank you @emoryuniversity.bsky.social for highlighting our recent study in NI! @natureportfolio.bsky.social (we did not make it to cover selection, but I love it anyway) #immunoSky Links url:https://news.emory.edu/stories/2025/01/er_lupus_and_mrna_15_01_2025/story.html rdcu.be/dZWI9 rdcu.be/d4332
Congrats @kevbonham.bsky.social! Great news! They are lucky to have you! Looking forward for exciting collaborations :) #immunoSky
Very excited to announce that the Bonham Lab will be starting next month at Tufts (TMC GI division)! I'll be recruiting at multiple levels - if you are interested in the intersection between computing and medicine, esp multi-'omics, microbio and immuno, reach out! #academicsky 🧪🧫🦠
New! @jenncoughlan.bsky.social kindly shared their MIRA NIH award with our github repo. If you have a successful grant app you're willing to share, please contribute! github.com/RILAB/statem...
GitHub - RILAB/statements: Successful Job Applications and Grants
Successful Job Applications and Grants. Contribute to RILAB/statements development by creating an account on GitHub.
github.com
Fantastic News & Views article Nature Portfolio by @michelalocci.bsky.social & @sapostolidis.bsky.social, highlighting our recent study on mRNA vaccines and SLE, its findings, and the key questions to address next! rdcu.be/d4332 #immunosky #SLE #mRNA #Bcells 🦠 👩🔬 💉
SLE B cells take an extrafollicular detour after mRNA vaccination
Nature Immunology - Systemic lupus erythematosus (SLE) is an autoimmune disease with considerable clinical heterogeneity and diverse treatment options. A study now shows that heightened...
rdcu.be
@johnmlindner.bsky.social It was a pleasure hosting you at #Emory! Thanks for sharing your remarkable insights into the T-Finder discovery pipeline. Excited for the collaborations ahead in T cells, B cells, and to more adventures in Atlanta’s diners with you and @eliverghosn.bsky.social #immunosky
Dr Kuchroo discussing the discovery and properties of TIM-3 and Tcf1 on T cells and beyond! @emoryuniversity.bsky.social #treg #dc #tim-3 #ImmunoSky
Totally agree! Fantastic scientist and human being!
Max deserves a Nobel. In the meantime, you can nominate someone for the Max Cooper Prize, deadline is April 1st. "Nomination letters of up to 3 pages must articulate how their research has led to advances in immunology research that will have a lasting impact." #Immunology
Like a photographer choosing between quick snapshots or careful portraits, our immune system balances fast action and precise antibody creation. @profshanecrotty @katyely.bsky.social @johnmlindner.bsky.social @cellpress.bsky.social @emoryuniversity.bsky.social t.co/E2WUBinqCd #ImmunoSky 🧪
✨ Ever wondered why B cells are so fond of IL-2? Wonder no more! Our study is now published in Immunity @cellpress.bsky.social 🔍📑 A truly perfect Thanksgiving gift! 🧑🔬💉🔬https://authors.elsevier.com/c/1kAq43qNrUxuTR
Hello BlueSky! 🌟 I am excited to be here and finally chat immunology, systems biology, and vaccines again. 🧪💡 Also, we’re growing our team in beautiful Tübingen (thanks to @ERC_Research) and looking for talent in #AI or #scRNAseq. There is still time to apply! 🚀 www.nature.com/naturecareer...
As part of my role as Head of Research for US-based BioMed X teams: Alicia Cutler's Team CHM (based in New Haven, CT) is #recruiting an #immunology expert (postdoctoral fellow) to study the role of #inflammation in #vasculature using unique, complex, 3-D models: career.bio.mx/call/2024-NH...
BioMed X Institute
BioMed X Application System
career.bio.mx
To be fair, the natural variety is not doing great on this front either. "Lack of internal deliberation abilities — thinking, in other words — has long been considered one of the main weaknesses of artificial intelligence." Yoshua Bengio on the FT www.ft.com/content/8946...
AI can learn to think before it speaks
Advances in reasoning will lead to substantially improved capabilities in mathematics and science
ft.com