Lydia Lynch
@lydialynch.bsky.social
Professor at Princeton University. Immunologist, Irish Mammy, Optimist
Obesity, adipose tissue, and systemic metabolism in cancer on the first session of #CFM_MetCanc. Speakers: Paul Cohen @rockefeller.edu Stephan Herzig @helmholtzmunich.bsky.social @lydialynch.bsky.social @ludwigcancer.bsky.social ✍️ https://bit.ly/45jaORu Sponsored by @caixaresearch.bsky.social
Our next #FusionMetabolism meeting unites researchers across the spectrum; from investigating individual molecules to carrying out population studies & clinical trials👩🔬 Submit by 13 April 2026 to join the line up ➡️https://bit.ly/45CT3MY @petemullen.bsky.social @annakrook.bsky.social
Super brilliant talk by Shruti @drshrutinaik.bsky.social visiting us in Princeton today 🐅 @princetonmolbio.bsky.social on new frontiers for the immune system in health, and co-opted in disease
He’s a doctor 🎉 Congratulations Dr Martin Brennan @princetonmolbio.bsky.social @tbsi-tcd.bsky.social We’re going to miss him so much! Onwards and upwards
Diabetes drug metformin causes weight loss by triggering the production of an "anti-hunger" molecule called lac-phe, also produced after vigorous exercise. #Metformin #WeightLoss #LacPhe #GutBrainConnection
Metformin's Weight Loss Effect Linked to "Anti-Hunger" Molecule Produced During Exercise
A new study conducted by researchers at Stanford Medicine and Harvard Medical School has found that the diabetes medication metformin causes weight loss
scienceblog.com
This was a labor of love requiring lots of teamwork over years, repeating in 3 locations! Thanks to all the lab over the years, giving their time generously to this team project, & our wonderful collaborators. The source of fat matters for anti-tumor immunity 🐄🐖🧈🌴🫒🥥 www.nature.com/articles/s42...
The source of dietary fat influences anti-tumour immunity in obese mice - Nature Metabolism
This study shows that animal-based high-fat diets accelerate tumour growth and impair anti-tumour response to melanoma in obese mice, whereas plant-based high-fat diets do not.
nature.com
ICYMI: Ascites-derived Lipid Uptake Drives NK Cell Dysfunction in Ovarian Cancer, a #ResearchWatch summary of a new study by @karen--s.bsky.social, @lydialynch.bsky.social, and colleagues at @ludwigcancer.bsky.social @princetonmolbio.bsky.social aacrjournals.org/cdnews/news/...
Ascites-derived Lipid Uptake Drives NK Cell Dysfunction in Ovarian Cancer
Major Finding: Lipids derived from ascites are taken up by NK cells and drive NK cell dysfunction in ovarian cancer. Concept: Polar lipids such as phosphatidylcholine disrupt NK plasma membrane order ...
aacrjournals.org
www.nature.com/articles/s41... @jkuball.bsky.social @sotnom.bsky.social @lydialynch.bsky.social @labminguet.bsky.social
Disrupting the balance between activating and inhibitory receptors of γδT cells for effective cancer immunotherapy
Nature Reviews Cancer - In this Review, Beringer and colleagues highlight how future strategies for developing immunotherapies using γδT cells and their receptors will depend on creating...
nature.com
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Our paper @sciimmunology.bsky.social shows certain lipids are responsible for the immunosupression of ascites & propose blocking lipid uptake thru SCARB1 may help immunotherapy in ovarian cancer. Wonderful to collaborate with Donal Brennan, Marcia Haigis & super postdoc @karen--s.bsky.social
Ludwig Cancer Research@ludwigcancer.bsky.social · last yr.Researchers led by Ludwig Princeton’s @lydialynch.bsky.social report that certain fats in ascites fluid—which accumulates as ovarian cancer spreads from the ovaries into the abdomen—sabotage anti-tumor immune responses and show how this effect might be blocked for immunotherapy. bit.ly/4jGuUtU
Researchers led by Ludwig Princeton’s @lydialynch.bsky.social report that certain fats in ascites fluid—which accumulates as ovarian cancer spreads from the ovaries into the abdomen—sabotage anti-tumor immune responses and show how this effect might be blocked for immunotherapy. bit.ly/4jGuUtU
A beautiful day in Princeton @princeton.bsky.social to host our Ludwig Distinguished speaker Dr Kivanc Birsoy from Rockefeller @ludwigcancer.bsky.social
Delighted to have taken part in this project that was published today led by Tomas Ryan’s lab @tjryan.bsky.social @tcddublin.bsky.social @tbsi-tcd.bsky.social ….. mice remember cold 🐭📝❄️
Princeton MolBio@princetonmolbio.bsky.social · last yr.Immunologists and neuroscientists collaborate to show experience of cold temps leaves a lasting impression on the brain. In Nature paper today by labs of Princeton's Lydia Lynch @lydialynch.bsky.social and Trinity College Dubin's Tomás Ryan @tjryan.bsky.social. molbio.princeton.edu/news/2025/co...
HANG IT IN THE LOUVRE. (President of Mexico on International Women’s Day)
NIH budget: $ 48b Musk wealth: $351b Both are mostly funded by your tax dollars But only one might save your life . . . . Sources: www.nih.gov/about-nih/wh... Search results: elon musk net worth g.co/kgs/6c8YEuB @standupforscience.bsky.social
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g.co
Thank you to our colleagues @pasteur.fr Paris 🇫🇷🥼🧪 #standupforscience
Institut Pasteur Education@pasteuredu.bsky.social · last yr.📢Aujourd'hui l'Institut Pasteur se mobilise pour la science, l'inclusion & l'avenir du savoir avec l'organisation du symposium «Excellence Scientifique : et si l'inclusion était la clé ?» en écho avec la Journée Internationale des Droits des Femme & la participation au mouvement #StandUpForScience !
Thank you to our colleagues in Geneva #standupforscience
Angela Huttner @angelahuttner.bsky.social · last yr.Good morning, US colleagues! In Switzerland, we'll speak up for you and #science everywhere! #Standupforscience walkout in #Geneva So many came even with little notice ☺️ We'll stay with you, and we'll only grow 🙏🏼 to the great leadership of #unige #ScienceSky #MedSky #EpiSky
Francis Collins, the NIH Director for 12 years, led the Human Genome Project and other NIH efforts for 32 years, resigned today. Key words from his resignation letter www.nytimes.com/2025/03/01/u...
So happy to have @aiinglim.bsky.social as a colleague at Princeton! Her immunology is so exciting and original 😍 Great talk at Princetons ‘Quantitative Immunology’ Symposium today @princetonmolbio.bsky.social
First measles death in Texas. Unfortunately, not surprising. Number of cases likely to increase and we may see more deaths. A tragic, preventable death of a school aged child. But the outbreak is called "not so unusual" by RFK. Simply not true. This is both unusual AND preventable. #vaccineswork
Congratulations to the amazing @karen--s.bsky.social ! And many thanks to @irishcancersociety and Prof Donal Brennan in @ucddublin.bsky.social for continued collaboration on gynaecological cancer research
Karen Slattery@karen--s.bsky.social · last yr.I was honored to recieve the Translational Project of the Year Award at the Irish Cancer Society Awards last week! Thanks so much to the ICS for funding and acknowledging this work, and to @lydialynch.bsky.social for all of the support over the years! 😊🥰
Almost ready to kick off the 3rd Fusion Mitochondria Conference in DR 🇩🇴🌴☀️🧬🧪🧫 @fusionconf.bsky.social with @MarciaHaigis
Hello DR 🇩🇴 just like Ireland, but 85degrees F! Can’t wait fo r the @fusionconf.bsky.social Mitochondria Conference!
We have to fight now for research that we know benefits all of humanity, we have to stand up for our colleagues at the NIH, we can’t lie down and take it, we stand against this madness #standupforscience2025
Stand Up for Science!@standupforscience.net · last yr.Welcome to the Bluesky account for Stand Up for Science 2025! Keep an eye on this space for updates, event information, and ways to get involved. We can't wait to see everyone #standupforscience2025 on March 7th, both in DC and locations nationwide! #scienceforall #sciencenotsilence
No one could be more deserving. The Immunology community is so proud of you @belkaidlab.bsky.social
Institut Pasteur | 130 years of biomedical research@pasteur.fr · last yr.🎖️ Proud of our Managing Director, Yasmine Belkaid, named Chevalier de la Légion d'Honneur! A well-deserved honor for her pioneering work in immunology, microbiota & nutrition. Her research embodies the Pasteurian spirit of science for humanity! 👏 #Science #Immunology
Fantastic thought provoking talk today by @itaiyanai.bsky.social at 🐅 @princetonupress.bsky.social ….first how we lost our tails against strong pressure, and then how cells develop resistance to drugs 🧫🧬🧪
Thank you to @mcsinton.bsky.social @juanquintana.bsky.social and co-authors for this spotlight on the amazing IL-17 😊
Matthew Sinton 🏳️🌈@mcsinton.bsky.social · 2y agoDelighted to have had the opportunity to write this spotlight with @juanquintana.bsky.social and the lab, on the recent @lydialynch.bsky.social paper, showing rhythmicity of IL-17 expression in adipose! Fascinating paper, which raises loads of cool questions #immunosky www.cell.com/immunity/ful...
Service to the scientific community @cp-immunity.bsky.social www.cell.com/immunity/ful...
Service
There are many dimensions to scientific life. We asked investigators about the impact of service to the scientific community and beyond and how service has shaped their experience, perspective, and research path.
cell.com
