New in MCP press| A temporal phospho-acetylome atlas of human myogenesis identifies coordinated post-translational regulation. Learn more: www.mcponline.org/ar... #MolCellProt
ASBMB Journals
@asbmbjournals.bsky.social
The American Society for Biochemistry and Molecular Biology advances scientific knowledge by reducing barriers to research. ASBMB journals, JBC, MCP & JLR, are gold open access. www.asbmb.org/journals-news | #ASBMBJournals
Nominations are now open for the Journal of Lipid Research Jr. Associate Editor Program — a 3-year mentored editorial opportunity for early-career faculty (≤10 years post-terminal degree). Send nominations (CV included) to JLR@asbmb.org & learn more about the program: www.jlr.org/junior-assoc....
New in JLR press| The p53 – CerS6 interaction on the ER integrates p53 and sphingolipid signaling pathways in metabolic stress response. Learn more: www.jlr.org/article/... #JLipidRes
New in JBC press| Rational engineering of the Arabidopsis thaliana plant cysteine oxidase 4 active site can reduce biochemical activity and improve submergence tolerance. Learn more: www.jbc.org/article/... #JBiolChem
OK, not a "tremendous breakthrough", but it is nice to have it completed - the first project in the group, started after moving to @hhu.de years ago, as a part of CRC 1208 (1st C is for "collaborative"). Thanks to all the co-authors for the joint effort and resilence ✊🤓 www.jbc.org/article/S002...
Conformational dynamics of the membrane-anchored foldase LipH from Pseudomonas aeruginosa governs recognition and release of its client lipase
The lipase LipA from Pseudomonas aeruginosa is an extracellular enzyme that plays an important role in bacterial infections. Prior to its export via the type II secretion system, LipA requires the cog...
jbc.org
And it was a great experience to publish in J Biol Chem @asbmb.bsky.social: from rapid processing by the Editorial office (out for reviewing in 48 hours!) to quick and constructive peer-review. 🌟
New JLR virtual issue: Lipids & Inflammation Discover how lipids regulate inflammation, tissue repair and host defense through unique signaling pathways. All articles are free to read. ➡️ Access the collection: www.jlr.org/content/lipi... #Immunology #JLipidRes #ASBMBJournals
Integrating condensates into protein lifespan – from birth to death - Journal of Biological Chemistry www.jbc.org/article/S002... @asbmbjournals.bsky.social
Integrating condensates into protein lifespan – from birth to death
Proper protein production is an essential biological process for all known living organisms. The cell depends on a functional protein homeostasis, or proteostasis, network to facilitate proper gene ex...
jbc.org
New in MCP press| Both L-lactyl and D-lactyl enantiomers modify histones in mouse testis. Learn more: www.mcponline.org/ar... #MolCellProt
New in JLR press| Mechanisms of scramblases in regulating hepatic lipoprotein secretion and autophagy. Learn more: www.jlr.org/article/... #JLipidRes
New in JBC press| Mitochondrial permeability transition in redox homeostasis and ferroptosis. Learn more: www.jbc.org/article/... #JBiolChem
The Journal of Lipid Research continues to lead at the forefront of emerging areas, including genomics, proteomics, metabolomics & lipidomics, as they relate to lipid biology. ⏯️Co-Editor-in-Chief Kerry-Anne Rye shares tips for writing a strong abstract. ✅Submit your work: www.jlr.org/call-for-pap...
The Journal of Biological Chemistry is part of the ASBMB journals portfolio—advancing progress across the molecular life sciences through rigorous, transparent peer review. 🔬 Submit your work and drive what’s next in life science discovery: www.jbc.org. #JBiolChem | @asbmb.bsky.social
Higher-order structural organization of mitochondrial metabolism - Journal of Biological Chemistry www.jbc.org/article/S002... @asbmbjournals.bsky.social
Higher-order structural organization of mitochondrial metabolism
The mitochondrion embeds numerous metabolic, biosynthetic, and signaling pathways occurring within its specialized compartments that collectively define eukaryotic biology. To visualize these, cryogen...
jbc.org
Structural basis of glucosinolate recognition and polyspecific transport by the glucosinolate transporter GTR1 - Journal of Biological Chemistry www.jbc.org/article/S002... @asbmbjournals.bsky.social
Structural basis of glucosinolate recognition and polyspecific transport by the glucosinolate transporter GTR1
Glucosinolates (GLSs) are sulfur-rich secondary metabolites characteristic of Brassicales and play central roles in plant defense. While the biosynthesis and long-distance allocation of GLSs have been...
jbc.org
New in JBC press| Scientists present a comprehensive account on the functions of SRCs in immunity and discuss how their pharmacological targeting. Learn more: www.jbc.org/article/... #JBiolChem
How do lipids shape immunity and disease? The Journal of Lipid Research is seeking submissions for its Lipids and Immunology collection, including research on inflammation, immune metabolism, lipid signaling and cancer. Submit: www.editorialmanager... #Immunology #LipidResearch #JLipidRes
🎨 The April 2026 cover image depicts mitochondrial trafficking along axonal microtubules driven by Kinesin-1 motors. The BPA molecule interacts with the Kinesin-1 motor domain, interfering with the normal bidirectional transport system. 📝 Article by Phoolmala et al.: www.jbc.org/article/S002....
The Journal of Biological Chemistry is part of the ASBMB journals portfolio—advancing progress across the molecular life sciences through rigorous, transparent peer review. 🔬 Submit your work and drive what’s next in life science discovery: www.jbc.org. #JBiolChem | @asbmb.bsky.social
The Journal of Biological Chemistry is part of the ASBMB journals portfolio—advancing progress across the molecular life sciences through rigorous, transparent peer review. 🔬 Submit your work and drive what’s next in life science discovery: www.jbc.org. #JBiolChem | @asbmb.bsky.social
New #openaccess #massspec publication in @asbmbjournals.bsky.social Molecular & Cellular Proteomics #MCP to decipher the dynamic proximity networks of myosin-19 (Myo19) and its mitochondrial receptors @uni-muenster.de Faculty of #Biology @ifink-lab.bsky.social and #IIZP doi.org/10.1016/j.mc...
Redirecting
doi.org
Researchers at @winshipcancer.emory.edu have developed a new proximity-labeling method to identify the proteins that interact with tau during aggregation, uncovering hundreds of tau-associated proteins linked to neurodegenerative disease. 🧠 Read about the findings: www.asbmb.org/asbmb-today/....
Catching tau in the act
Using a new proximity-labeling approach, researchers reveal how tangles of the brain-associated protein tau may disrupt RNA biology long before neurons die.
asbmb.org
New in MCP press| 4-Oxo-2-Nonenal Crosslinks Vicinal Cysteine-Lysine Pairs in Cellular Proteins. Learn more: www.mcponline.org/ar... #asbmbMCP
The protein phosphatase 2A-B56α complex regulates N-Myc degradation in neuroblastoma - Journal of Biological Chemistry www.jbc.org/article/S002... excited to share new research for our group identifying a novel approach to target a major driver of pediatric neuroblastoma
The protein phosphatase 2A-B56α complex regulates N-Myc degradation in neuroblastoma
High-risk neuroblastoma is one of the most common and deadliest pediatric solid tumors. Proliferation, differentiation, and treatment resistance have been linked to the amplification of MYCN. Although...
jbc.org
Congratulations to Jennifer Heritz and Katherine Meluni! They were selected winners for the 2026 Journal of Biological Chemistry/Herbert Tabor Early Career Investigator Award. "Integrating deep learning for posttranslational modifications crosstalk on Hsp90 and drug binding"
Structure-function analysis of the bacterial ClpE/ClpP AAA+ protease - Journal of Biological Chemistry www.jbc.org/article/S002... @asbmbjournals.bsky.social
Structure-function analysis of the bacterial ClpE/ClpP AAA+ protease
General and regulatory proteolysis in bacteria is executed by a set of ATP-dependent proteases composed of hexameric ring-forming AAA+ proteins and associated peptidase barrels (e.g. ClpP). These AAA+...
jbc.org
Structure-function analysis of the bacterial ClpE/ClpP AAA+ protease - Journal of Biological Chemistry www.jbc.org/article/S002...
Structure-function analysis of the bacterial ClpE/ClpP AAA+ protease
General and regulatory proteolysis in bacteria is executed by a set of ATP-dependent proteases composed of hexameric ring-forming AAA+ proteins and associated peptidase barrels (e.g. ClpP). These AAA+...
jbc.org
S-acylation and membrane localization of the small GTPase ARL15 are mediated by the Golgi S-acyltransferases ZDHHC7 and ZDHHC3. Hearty congratulations, Kenji Kontani and all coauthors. #proteinpalmitoylation #proteinlipidation - Journal of Biological Chemistry www.jbc.org/article/S002...
S-acylation and membrane localization of the small GTPase ARL15 are mediated by the Golgi S-acyltransferases ZDHHC7 and ZDHHC3
ARL15 is a member of the ARF-like (ARL) family of small GTPases, implicated in the regulation of ion homeostasis and metabolic signaling pathways. Although ARL15 has been suggested to undergo S-acylat...
jbc.org
New📜 from our lab provides a mechanism for how gut Bacteroides evolve effector repertoires secreted by conserved T6SSs, shaping competition and gut biodiversity 🦠 Heteromeric Hcp proteins recognise and “carry” multiple effectors minimizing protein sequence variability 🧬 doi.org/10.1016/j.jb...
JBC must ensure that it continues to capture the most meaningful advances in molecular and biochemical biology, while maintaining the standards that define its identity. In aligning with a changing field, JBC will be expanding its scope. ➡️ Read the full editorial: www.jbc.org/article/S002....