The most sensitive green and red #norepinephrine #sensors engineered to date are out in #naturemethods! Deeply grateful to all our funders and contributors who made this work possible. A true team effort. @erc.europa.eu @snsf.ch doi.org/10.1038/s415...

Next-generation multicolor indicators for in vivo imaging of norepinephrine - Nature Methods

Improved red and green indicators for norepinephrine and their characterization are reported. These indicators allow detection of norepinephrine release in awake behaving mice in dual-color fiber phot...

doi.org

New preprint alert, from a collaboration with @labluthi.bsky.social and Valerio Zerbi lab at Synapsy Center #GenevaUniversity - great collaboration, special thanks to Francesca Barcellini and Georgios Foustoukos for realizing this work ! www.biorxiv.org/content/10.6...

A commentary on reptile sleep, with recommendation from @anitaluthi.bsky.social @labluthi.bsky.social

The Transmitter @thetransmitter.bsky.social · 8mo ago

A new comparative study of seven lizard species, including chameleons and bearded dragons, finds an ancient sleep rhythm conserved over millennia. By Lauren Schenkman www.thetransmitter.org/sleep/snoozi...

@labluthi.bsky.social sends Season's Greetings to all, we look forward meeting you for scientific exchange in 2026!

Paper alert! I’m very pleased to announce the publication of my PhD work, which I carried out under the amazing supervision of Clément Menuet at @inmed.bsky.social ! Link to the paper in @natneuro.nature.com: www.nature.com/articles/s41... #RespHRV #oxytocin #RSA #brainstem #HRV

Oxytocin modulates respiratory heart rate variability through a hypothalamus–brainstem–heart neuronal pathway - Nature Neuroscience

Buron et al. show that oxytocin enhances heart rate variability linked to breathing during recovery from stress. This calming and cardio-protective effect is produced through a hypothalamus–brainstem ...

nature.com

Oxytocin modulates respiratory heart rate variability through a hypothalamus–brainstem–heart neuronal pathway @julie.buron.bsky.social @inmed.bsky.social @insermpacacorse.bsky.social D54@incia-neurocampus.bsky.social www.nature.com/articles/s41...

Oxytocin modulates respiratory heart rate variability through a hypothalamus–brainstem–heart neuronal pathway - Nature Neuroscience

Buron et al. show that oxytocin enhances heart rate variability linked to breathing during recovery from stress. This calming and cardio-protective effect is produced through a hypothalamus–brainstem ...

nature.com

@labluthi.bsky.social congratulates Lila Banterle for her successful PhD thesis - an excellent defense was followed by excellent festivities! @anitaluthi.bsky.social @fbm-unil.bsky.social

Congratulations to @anitaluthi.bsky.social and @manumameli.bsky.social 🎓👏 www.linkedin.com/posts/depart...

Two new full professorships strengthen neuroscience at UNIL! | Department of Fundamental Neurosciences - DNF, University of Lausanne

Two new full professorships strengthen neuroscience at UNIL! We are delighted to announce that two leading researchers from the Department of Fundamental Neurosciences (DNF) of the FBM UNIL - Faculté...

linkedin.com

Our conclusion: there is a signature of IH in sleep but the causes might be found in wake! Thanks @institutducerveau.bsky.social, @inserm.fr, @aphp.bsky.social and @erc.europa.eu for supporting this work!

And here is the preprint: www.biorxiv.org/content/10.1...

EEG Signature of Idiopathic Hypersomnia: Insights from Sleep Microarchitecture and Hypnodensity Metrics

Background and Objectives: Patients with idiopathic hypersomnia with long sleep time (IH) report daytime hypersomnolence despite prolonged sleep time and normal sleep macrostructure. As they often hav...

biorxiv.org

@LabLuthi congratulates Dr. Georgios Foustoukos for the Best Publication Award 2025 from the #SSSSC, the #Swiss Society for #Sleep Research, Sleep Medicine and #Chronobiology. A nice recognition of your outstanding experimental and analytical skills!👏 @fbm-unil.bsky.social @natneuro.nature.com

👉👉new paper alert from @labluthi.bsky.social - so proud for talented and determined Dr.Najma Cherrad who opened the lab‘s access to brain-body communication! #sleep #locuscoeruleus #parasympathetic @fbm-unil.bsky.social

bioRxiv Neuroscience@biorxiv-neursci.bsky.social · last yr.

Vagal afferent activation induces a NREM-sleep-like state with brain-body cooling, but locus coeruleus activation https://www.biorxiv.org/content/10.1101/2025.03.14.643122v1

👉👉new paper alert from @labluthi.bsky.social - so proud for talented and determined Dr.Najma Cherrad who opened the lab‘s access to brain-body communication! #sleep #locuscoeruleus #parasympathetic @fbm-unil.bsky.social

bioRxiv Neuroscience@biorxiv-neursci.bsky.social · last yr.

Vagal afferent activation induces a NREM-sleep-like state with brain-body cooling, but locus coeruleus activation https://www.biorxiv.org/content/10.1101/2025.03.14.643122v1

Can you learn while sleeping? Does sleep help you solve problems? What is the effect of sleep on brain metabolism? --> my last editorial @braincomms.bsky.social doi.org/10.1093/brai... Sleep is not a homogenous state - just like wake. Asking the role of sleep is as fair as asking the role of wake!

Here's our latest issue: www.cell.com/neuron/current The cover is for a Perspective piece by Lüthi & Nedergaard who discuss microarousals, and propose an inverted U-shaped relationship to reconcile their essential and disruptive roles: www.cell.com/neuron/fullt... Cover by Nadia Alzoubi

What a pleasure to be interviewed by science writer @davidarobson.bsky.social, what an even greater pleasure to read his visionary narrative in BBC future!

David Robson@davidarobson.bsky.social · 2y ago

My latest for the BBC explores how the brain's "little blue dot" regulates our sleep, which is inspiring new ways to treat insomnia. I was especially interested to know that yoga/slow breathing in the evening may reduce micro-awakenings at night, which I now use myself www.bbc.com/future/artic...

@anitaluthi.bsky.social

Pierre Champetier@champetier-pierre.bsky.social · 2y ago

Research on infraslow oscillations during NREM sleep is definitely a hot topic ! 🔥 New paper making the link between norepinephrine oscillations and glymphatic clearance 🧠🚿 @cellcellpress.bsky.social @nataliehauglund.bsky.social www.cell.com/cell/abstrac...

Important study on the timing pattern of #sleep #spindles in human EEG and of fingerprints that characterize individuals across age and demographic factors 👏👏

Laurent Sheybani@laurentsheybani.bsky.social · 2y ago

Timing of spindles are governed by individual rules --> doi.org/10.1073/pnas... @anitaluthi.bsky.social @labnir.bsky.social @vyazovskiy.bsky.social

Amazing work from the team of Anita Lüthi! Infraslow noradrenergic locus coeruleus activity fluctuations are gatekeepers of the NREM–REM sleep cycle www.nature.com/articles/s41... 💤🧪🧠

Infraslow noradrenergic locus coeruleus activity fluctuations are gatekeepers of the NREM–REM sleep cycle - Nature Neuroscience

Lüthi and colleagues show that activity of the locus coeruleus (LC) is crucial for the cyclic alternation between non-rapid-eye-movement and rapid-eye-movement sleep. Stressful experiences during waki...

nature.com

Alors c’est parti: 1er post, en français: Récente découverte @unil.bsky.social: une toute petite région du cerveau qui s’appelle « locus coeruleus » détermine si nos nuits sont bien rhythmées entre les phases du #sommeil paradoxal et profond. www.unil.ch/news/1723726...

Une nouvelle horloge pour structurer le sommeil

Des scientifiques au sein de la FBM-UNIL ont identifié un nouveau rôle du locus cœruleus dans le sommeil et ses troubles. Cette région cérébrale permet la transition entre les états du sommeil et le m...

unil.ch

🔵 blue spot alert: Anita Luethi's team reports a dual role of #locuscoeruleus in #sleep in Nature Neuroscience @natureportfolio.bsky.social 1) high LC activity facilitates cortical microarousals 2) low LC activity is required for NREMS-to-REMS transitions doi.org/10.1038/s415...

Infraslow noradrenergic locus coeruleus activity fluctuations are gatekeepers of the NREM–REM sleep cycle - Nature Neuroscience

Lüthi and colleagues show that activity of the locus coeruleus (LC) is crucial for the cyclic alternation between non-rapid-eye-movement and rapid-eye-movement sleep. Stressful experiences during waki...

doi.org