Our recent review on #microglia and brain #organoids is getting a good reception! 🧠🧪 onlinelibrary.wiley.com/doi/full/10....
Amanda Sierra
@sierralab.bsky.social
Research professor at Achucarro Basque Center for Neuroscience. Microglial lover, passionate about science outreach. ORCID: 0000-0001-8415-096X Lab website: https://www.achucarro.org/es/laboratory/glial-cell-biology/
Join us if you want to learn about #microglia!
Sociedad Española de Bioquímica y Biología Molecular (SEBBM)@sebbm.bsky.social · 12mo ago🗓️El próximo 16 de septiembre a las 16h "Webinar Grupo Neurobiología Molecular" coordinado por @pgonzalezrodriguez.bsky.social 🗣️ @sierralab.bsky.social “Brain scavengers: microglial phagocytosis in health and disease ✍️ https://f.mtr.cool/fawelesych
Are you interested in human brain #organoids to study #microglia but don't know where to start?🧠🧪 #neuroskyence Here's our piece of advice on "Building Immunocompetent Cerebral Organoids From a Developmental Perspective" onlinelibrary.wiley.com/doi/10.1002/...
Building Immunocompetent Cerebral Organoids From a Developmental Perspective
Conventional cerebral organoids do not contain microglia, which must be added. We propose recommendations to assess microglial immunocompetence using quantitative approaches and stringent statist...
onlinelibrary.wiley.com
The @sierralab.bsky.social lab is hiring! Postdoctoral position in #microglial development (#IKUR) www.achucarro.org/job/postdoct...
Reaching Marseille was quite an odissey because of the wildfires, but the #Euroglia meeting was quite a success! Tons of science, friends and fun!
This sounds sooo familiar So, maybe, "The next time we hear a crazy/bitch narrative about a senior woman, let's ask ourselves: How much first-hand evidence do we personally have to back it up -- does it resonate with our own direct observations and interactions with her?"
Needhi Bhalla 💅🏽@needhibhalla.bsky.social · last yr.“How might the narrative about senior women be challenged or changed in order to respect these women who have achieved enough success to earn promotion? How do we stop this generational cycle so that women's wings aren't clipped as soon as they approach the power to soar.”
#Cellpose 3 paper now out. Not all images are perfect. Restore your images with Cellpose3 to get better segmentations, w/ @marius10p.bsky.social www.nature.com/articles/s41...
Even in the absence of formal instruction to do so, we should continue to hold ourselves and our neuroscience colleagues accountable for “Sex as a Biological Variable” practices, writes @docbecca.bsky.social. #neuroskyence www.thetransmitter.org/sex-differen...
Amid NIH upheaval, how to keep sex as a biological variable
Even in the absence of formal instruction to do so, we should continue to hold our colleagues accountable for SABV practices.
thetransmitter.org
Francis Collins, the NIH Director for 12 years, led the Human Genome Project and other NIH efforts for 32 years, resigned today. Key words from his resignation letter www.nytimes.com/2025/03/01/u...
🗣️ℹ️How do we prevent misinformation? By talking about it, without reservations and full openness. 🧫🐁It is the same with science communication and #AnimalResearch specifically. 💉💡Even if you somehow oppose it… know why it is still needed.
EARA@eara.eu · last yr.📄 We have updated our popular website information page '40 reasons why animals are needed for #BiomedicalResearch'. 🔬 The page which presents compelling reasons why #AnimalResearch continues to be essential in medical advances & scientific discovery. www.eara.eu/post/40-reas...
This is today. No recording, so it won't be available in our website. Don't miss it!
European Microglia Webinar Series@microgliaseries.bsky.social · 2y ago📢New webinar coming soon📢 Dr. Gilbert Di Paolo from Denali Therapeutics will be our next speaker on February 4th. Check all the information in the flyer and add it to your calendar!
I would love to hear your views on this article. I discuss some hurdles I faced when thinking about experiments and projects design. This is something no one formally teaches you. network.febs.org/posts/thinki...
Thinking like a scientist: not that trivial
network.febs.org
🧪🧠
Shane Liddelow@liddelowsa.bsky.social · 2y ago#GliaPapers #GliaFebruary2025 RESEARCH Noelia Rodriguez-Iglesias, …, Simon Gutbier, @sierralab.bsky.social Bottom-up approach identifies antipsychotic & antineoplastic trifluoperazine & ribose derivative deoxytubercidin as microglial phagocytosis inhibitors onlinelibrary.wiley.com/doi/10.1002/...
Interested in pursuing a PhD in neuroimmunology and metabolism? Apply to this call to work on a collaborative project between my group and @cmadore.bsky.social !
Charlotte Madore@cmadore.bsky.social · 2y ago🧠Talented future PhD students in Neuroscience/Nutrition !!! Do not hesitate to apply to this great PhD program at Bordeaux University🧠 (the call ends soon) 🧠🤯🧪 www.bordeaux-neurocampus.fr/phd-call-2025/
"The human mind is not, like ChatGPT a lumbering statistical engine for pattern matching, gorging on terabytes of data and extrapolating the most likely conversational response, most probable answer to a scientific question" Noam Chomsky: The False Promise of ChatGPT www.nytimes.com/2023/03/08/o...
Opinion | Noam Chomsky: The False Promise of ChatGPT (Published 2023)
The most prominent strain of A.I. encodes a flawed conception of language and knowledge.
nytimes.com
📢New webinar coming soon📢 Dr. Gilbert Di Paolo from Denali Therapeutics will be our next speaker on February 4th. Check all the information in the flyer and add it to your calendar!
Contact me if you are interested in pursuing an independent position in Neuroscience 🧪🧠 at Achucarro @achucarro.bsky.social calls.ikerbasque.net
Any #SpatialTranscriptomics people out there interested in studying #microglial development? We need a collaborator based in the Americas or Asia to apply for a #HSPF grant www.hfsp.org/funding/hfsp...
Research Grants | Human Frontier Science Program
hfsp.org
“‘It’s very easy to assume that science is going to change organically towards equality — and what this study shows is that that’s not happening…It is an ‘important reminder for us that we need to stay vigilant in working towards equality in science’” @crsugimoto.bsky.social 🧪 #AcademicSky 👩🏽🔬
Who’s quitting academia? Data reveal gender gaps in surprising fields
Even in scientific areas in which women are well represented, they are up to 40% more likely than men to leave research within 20 years.
nature.com
I think the field needs to reconsider the widespread concept that microglia are The most important factor controlling synaptic pruning.🧠🧪 We offered our Perspective on whether they are hunters or gatherers of synaptic debris here www.nature.com/articles/s41...
Microglia as hunters or gatherers of brain synapses - Nature Neuroscience
How microglia sculpt brain circuits is not clear. Here, the authors propose that their contribution to synapse removal may occur by severing synapses (culling) or collecting synapses shed off by neuro...
nature.com
Nature Neuroscience@natneuro.nature.com · 2y agoMice lacking microglia (Csf1r∆FIRE/∆FIRE) have normal -synapse number and maturation -seizure susceptibility and hippocampal-prefrontal cortex coherence -segregation of inputs into the lateral geniculate nucleus -neuronal and astrocytic gene expression www.nature.com/articles/s41...
Happy to share our Perspective on #microglia #pruning and help to answer the questions of whether they are hunters or gatherers of brain #synapses 🧠🧪 #neuroskyence nature.com/articles/s4159…
The call is now open! Junior postdocs deadline: Jan 17 Senior postdocs deadline: Jan 21
Amanda Sierra@sierralab.bsky.social · 2y ago#Microglia lovers, winter is coming and along will come the #JuanDeLaCierva and #RamonyCajal calls for junior and senior postdocs! DM or email me if you are interested in learning how risk genes for neurodegenerative diseases affect microglial early development.
#Microglia lovers, winter is coming and along will come the #JuanDeLaCierva and #RamonyCajal calls for junior and senior postdocs! DM or email me if you are interested in learning how risk genes for neurodegenerative diseases affect microglial early development.
Here is the new account in Bluesky that every #microglia lover or afficionado should follow.🧪 You can find a repository of previous talks at www.achucarro.org/es/european-...
European Microglia Webinar Series - Achucarro Basque Center for Neuroscience
European Microglia Webinar Series As from October 2023 a group of researchers of the University of Lausanne (CH) and ACHUCARRO have taken over the organization of the European Microglia webinar series...
achucarro.org
European Microglia Webinar Series@microgliaseries.bsky.social · 2y agoWelcome to the European Microglia Webinar Series! Here you will find the information and link to every webinar, so dont forget to follow us
Anybody else experiencing problems with #primerblast? It takes forever or doesn't work at all! Alternatives for designing #qPCR primers, anybody? 🧪
Look @eara.eu , another example of animal research succesfully leading to human therapies
Diego García González@diegoconcalma.bsky.social · 2y agoFirst, in rats (PMID: 22654062); then, in primates (PMID: 27830790); and now in humans (again) nature.com/articles/s41... This is precisely why we need animal research! Huge congratulations to the authors on this impressive work!