Radoslaw (Radek) Szmyd
@szmyd-radoslaw.bsky.social
DSB repair and DDR centred scientist 🧬 Based in Sydney 🇦🇺 CrossFit/fitness 🏋🏻 Food 🍱 and traveling 🌏 enthusiast
One of the most exciting stories I have come across lately. Congrats to all authors 👏🏻
Peter Ly@peterlylab.bsky.social · 3mo agoExcited to share our latest paper! We found that large pieces of the human genome can transfer between cells upon direct contact, endowing recipient cells with heritable phenotypic changes. @cp-cell.bsky.social (1/7) www.cell.com/cell/fulltex...
📣 Applications Now Open: 2026 ACDS Professional Development Award 📣 (1/6) ACDS members are invited to apply for the 2026 ACDS Professional Development Award, designed to support early-career researchers in taking part in professional development opportunities and advancing their career!
For researchers living on Australia’s east coast, this speaker lineup promises to be well worth staying awake until 1am 🙂
GIIN@genomeiinetwork.bsky.social · 4mo agoWe are excited to launch the full program for the 2026-2027 season of the Genome Integrity Italian Network webinars! Join us every first Tuesday of the month via Zoom: uzh.zoom.us/j/6598481621... Subscribe here to receive a calendar file with all webinars: docs.google.com/forms/d/e/1F...
Very cool video!
Spirochrome@spirochrome.com · 4mo agoMesmerizing light sheet imaging of neutrophils swarming at a yeast target! The neutrophils were labeled with SPY650-DNA (yellow) and a calcium dye (blue). This movie is part of the recent manuscript by @strickland-evelyn.bsky.social that we highly recommend reading! www.biorxiv.org/content/10.6...
Learn about the #DNAdamage response in #CellPhysiology and diseases in the eponymous EMBO Workshop in #Sounio, #Greece, 12–16 October 2026. Deadline: 17 May 2026 https://meetings.embo.org/event/26-dna-damage #EMBODNADamageResponse #genesky #LifeSciences #research #meeting #EMBOevents 🧪
Want to know how homologous recombination defects are caused upon loss of BRCA2? Check out our recent efforts in uncovering this phenomenon just out in Science! www.science.org/doi/10.1126/...
FIGNL1 inhibits homologous recombination in BRCA2 deficient cells by dissociating RAD51 filaments
Homologous recombination (HR) deficiency upon Breast Cancer Gene 2 (BRCA2) loss arises from defects in the formation of RAD51 nucleoprotein filaments. We demonstrate that loss of the anti-recombinase ...
science.org
🧬 Join us for the 2025 End-of-Year Cell Death Seminar & Networking Event! Hosted by the Australasian Cell Death Society, this hybrid event celebrates the latest in cell death research and discovery. See the flyer for full details 👇
The Cesare Lab had an excellent time at the Australian Cell Cycle, DNA Repair & Telomere Meeting in Melbourne. australiancellcycle.org A huge thank you to @genomestability.bsky.social and all the organisers for putting together such a fantastic and inspiring meeting. We're looking forward to 2027!
Had a great time at the Australian Cell Cycle, DNA Repair & Telomere Meeting in Melbourne with colleagues from @cmri.bsky.social and @thecesarelab.bsky.social. Three awesome days of inspiring talks, great discussions, and the amazing food Melbourne’s known for.
Thrilled to share my first podcast appearance 🎙️ with Prof. Nancy Baxter - a very special experience. We spoke about my research on how cancer cells die after radiotherapy and why it matters for long-term outcomes, as well as my scientific career path. 🔗 open.spotify.com/episode/1uBs...
Dr Radek Szmyd is uncovering how DNA repair pathways shape cancer cell death
open.spotify.com
🦘🧬Australian invited speaker list finalised for the 2025 Cell Cycle, DNA repair and Telomere Meeting! Friday 5 Sep is your last chance to register at the EARLY BIRD rate & submit an abstract 🤩 australiancellcycle.org/australian-i...
Australian Invited Speakers 2025
We are in the process of inviting a number of outstanding Australian leaders in the fields of DNA repair, Cell Cycle and Telomere biology. Current invited speakers include: Lisa Alcock, Curtain Uni…
australiancellcycle.org
Grateful to the University of Sydney for recognising the quality of my research with the Outstanding Publication Award 🎉, and to the Children’s Medical Research Institute for featuring it in their latest newsletter. Read more👇 🔗 www.cmrijeansforgenes.org.au/news/award-w...
Award-winning researcher
CMRI researcher Dr Radek Szymd won an award for his work on the impact of radiation on cancer
cmrijeansforgenes.org.au
(1/3) 🚨 We’re back with Edition #2 of our 2025 International Cell Death Seminar Series! 🚨 📅 Wednesday 3 Sept | 🦘 4:30pm AEST / 🌍 8:30am CEST In collaboration with @ecdoorg.bsky.social + @CDDpress. Flyer below ⬇️ #ACDS #CellDeath
The goal of a PhD is not to learn some facts or read a few papers or learn a bunch of techniques. The goal of a PhD is to learn independence, problem solving, how to finish things you start, resilience, & gain the ability to adapt & think creatively. Learning these things is hard.
1 in 20 children is born with a birth defect or genetic condition. I’m proud to work at @cmri.bsky.social alongside researchers who are working tirelessly to find cures for these diseases. Today is Jeans for Genes Day — all donations are doubled! Support CMRI! 👉 fundraise.jeansforgenes.org.au
We’re excited to contribute to the conversation on how genome maintenance and cell death intersect, and what this means for improving cancer outcomes.
Tony Cesare@thecesarelab.bsky.social · last yr.New from us in @natrevmcb.nature.com -- @szmyd-radoslaw.bsky.social & @radoncdocgee.bsky.social explore how DNA repair actively shapes cancer cell fate following DNA damage, reframing repair as both a protective process & a driver of treatment response and cell death. www.nature.com/articles/s41...
RaPID-seq looks like very cool technique that can benefit DDR and recombination fields
Jacob Corn@jcornlab.bsky.social · last yr.New #preprint from the lab! Do you want to see the invisible? So did we! When DNA genomes get broken, cells somehow find related sequences to fix the break. But how do they find it? We developed a way to look at sequence *search*, not just sequence usage. doi.org/10.1101/2025...
📢 Don’t forget! The next ACDS Seminar Series is TOMORROW Wednesday, 2 July at 11:00am AEST 🧬 🧠 Set your reminder & join us live
(1/3) 🔬 Excited to announce our next ACDS Seminar Series is coming up on Wednesday 2 July at 11am AEST! Join us to hear the latest in cell death research from two outstanding speakers. 🧠✨ View the poster for more info:
If your research oscillates around cell death, it’s not too late to join Australasian Cell Death Society and apply for Professional Development Travel Award for your next conference or an exchange/internship in a collaborator’s lab.
Australasian Cell Death Society (ACDS)@auscelldeathsoc.bsky.social · last yr.🚨 Applications for the 2025 ACDS Professional Development Award close soon! Don't miss your chance to secure $2,000 for travel or training. 🗓️ Deadline: 5pm AEST, Friday 6 June 📩 Apply now: australasiancelldeathsociety.com/acds-awards
The graphical visualisation and image analysis of these movies are awesome! Such a cool scientific approach to answer the big questions of DDR and repair field. Well done 🧬 🙌🏻
altmeyerlab@altmeyerlab.bsky.social · last yr.Sharing our latest work tracking DNA damage inheritance by Live+QIBC www.nature.com/articles/s41.... Huge congrats to @apanagopoulos.bsky.social, M. Stout and all co-authors for this tour de force! Beautifully summarized by @s-j-aitken.bsky.social & E. Reilly www.nature.com/articles/d41...
Excited to present Social DNAing tomorrow. I’ll talk about our work led by @szmyd-radoslaw.bsky.social in collaboration with @radoncdocgee.bsky.social. 12 pm Eastern USA Thanks Shan Zha for the invite. www.cancer.columbia.edu/research/pro...
Social DNAing
Social DNAing Webinar Series, sponsored by the Cancer Genomics and Epigenomics Program at Columbia University, aims to provide a virtual meeting room for the genomic instability community worldwide.
cancer.columbia.edu
Congratulations to Jenna Whalen on her Nature Cancer paper out today-a distinct take on nicks and their toxicity! rdcu.be/d60Td
Targeting BRCA1-deficient PARP inhibitor-resistant cells with nickases reveals nick resection as a cancer vulnerability
Nature Cancer - Whalen et al. report that increased DNA end resection in BRCA-deficient, PARP inhibitor-resistant cancers leads to increased sensitivity to DNA nicks, limiting tumor formation in...
rdcu.be
My research is finally out! Huge thanks to @thecesarelab.bsky.social, @radoncdocgee.bsky.social, and everyone involved for their invaluable support along the way. Briefly, we have demonstrated that cell cycle dependent DSB repair pathways guide death outcomes following lethal genomic damage.
Tony Cesare@thecesarelab.bsky.social · 2y ago1/Delighted to announce the newest paper from our lab, “Homologous recombination promotes non-immunogenic mitotic cell death upon DNA damage”, is out today in @naturecellbiology.bsky.social, www.nature.com/articles/s41....