Rémi Fronzes
@fronzeslab.bsky.social
🔬 CNRS Research Director, Bordeaux Structural biologist & microbiologist 🏃♂️ Runner & 🚴 Cyclist (mostly Velotaf) ⛰️ Mountain & nature lover 🏛️ Formerly at UCL/Birkbeck & Institut Pasteur 🦠 Trying to figure out how bacteria fight, defend & adapt
Je confirme. Très très fier de la GenZ. Leurs manifs sont juste géniales. Inclusives, joyeuses, engagées. Les vieux c..s ont du soucis à se faire.
Libération@liberation.fr · 4d agoAlors que la violence domine sa couverture médiatique, le mouvement, porté par ces jeunes que l’on disait anxieux, respire une joie éminemment politique.
Franchement @lemonde.fr, on attend mieux de vous. « Ont coûté » : le choix des mots n'est pas anodin. Les malades ne coûtent pas à la sécu. Ils sont aidés par la collectivité
Le Monde@lemonde.fr · 4d agoLes affections longue durée ont coûté près de 20 milliards d’euros à l’Assurance-maladie en 2025
La colère et le mal-être viennent de loin er sont profonds. La response du gouvernement est de absolument en dessous de tout !
France Universités@franceuniversites.bsky.social · 5d agoLa colère et le mal-être de cette jeunesse viennent de loin. [Communiqué de presse] France Universités appelle à mettre la jeunesse au cœur du débat public franceuniversites.fr/actualite/fr... #Présidencielle2027
La colère et le mal-être de cette jeunesse viennent de loin. [Communiqué de presse] France Universités appelle à mettre la jeunesse au cœur du débat public franceuniversites.fr/actualite/fr... #Présidencielle2027
How I arrived on blue sky (fleeing the blue bird)
The Birds Attack
ALT: The Birds Attack
static.klipy.com
BWJones@bwjones.bsky.social · 5d agoHow I arrived on blue sky
La genZ est dans la rue et elle est vraiment pas contente et très motivée
Four days ago, a scientist was surprised by the news that Anthropic discovered new virus genes for making DNA. He says he’s been studying them for years—and feeding his data to Anthropic’s AI as part of his own research. Coincidence? Here’s my story. nyti.ms/3VSWayc
Did Anthropic’s A.I. Really Make a Scientific Discovery on Its Own? (Gift Article)
An expert at the University of Copenhagen said his team had been sharing its research with the company’s A.I. model, Claude, and that its new finding matched their work.
nyti.ms
I'm excited to share our new preprint, where we show that fine-tuning gold nanoparticle conjugation to different Fab structural elements can produce powerful, rigidly coupled, labeling tools for in-situ cryo-ET. Take a look if you want to see an AuNP in an EM map!🔬🧠 www.biorxiv.org/content/10.6...
Next speaker for our @iecb.bsky.social seminar is Kira Gysel from @au.dk. This week Friday (25.09.2026, 11:00 AM) at the IECB auditorium. "Decoding the carbohydrate language of plant–microbe interactions" Open to the full scientific community of @univbordeaux.bsky.social @deptse-ub.bsky.social
yesterday was another perfect day for a little stroll in the mountains.
Oh mais ça a l'air pas mal du tout ça. Vivement que Emmy, Mistral et le CNRS nous propose la même chose 😬😭 #ESR #AI www.anthropic.com/research/cla...
How Claude is uplifting biomolecular modeling
Anthropic is an AI safety and research company that's working to build reliable, interpretable, and steerable AI systems.
anthropic.com
Really impressing MINFLUX tracking of molecular motors www.nature.com/articles/s41... #bioimaging
Characterizing dynamics of productive dynein stepping by MINFLUX - Nature Structural & Molecular Biology
Slivka et al. track dynein’s microtubule-binding domain with minimal fluorescence photon flux, revealing transient backward ‘dips’ before steps. These dips represent microtubule release upon ATP bindi...
nature.com
@cnrs banned Claude from our labs. We are not allowed to use it and cannot pay access to these ressources with research grants. This is a NONSENSE. We are wasting time and money. And above all undermine our competitiveness
Pedro Beltrao@pedrobeltrao.bsky.social · 3w agoAnthropic has used Claude to optimise structure prediction and design code to improve speed and memory efficiency. 2-3X speed improvements on AF3, 5X on OF3, 5X on BindCraft low memory modes to model large assemblies. All released as open source www.anthropic.com/research/cla...
Using Claude science for a « in silico » structural biology project. Definitely very useful to automate processing pipelines and data processing. But makes a lot of errors and is going in the wrong direction if not carefully guided and monitored. To be handled with great care
Finally a more intuitaive way to learn pLDDT/pAE? 😎 sokrypton.github.io/protein_figh... (Character idea from @hannes-stark.bsky.social & Alex Waldherr)
Here is the problem with IA leadership. One day they say something that seems reasonable (regulation, safeguards), and the next something completely nuts… It shows that these people cannot be trusted to manage such a sensitive technology.
The Guardian@theguardian.com · 2y ago‘Virtual employees’ could join workforce as soon as this year, OpenAI boss says
Can you tell how an antibiotic kills bacteria just by watching them under a regular microscope — without any dyes ? Yes, it turns out, at least if you are a deep neural net.
MemBrain v2 is on @natmethods.nature.com now? I never had a @biorxivpreprint.bsky.social with 164 citations before😅 ...Which is also to say: Thank you to the amazing #TeamTomo community, many of whom not only beta tested, but also contributed diverse training data. This one belongs to all of us! 🤗🔬🧪
Ricardo D. Righetto@lifeonthewedge.bsky.social · last mo.A wild publishing ride to get here... but finally! (first bioRxiv: January 5th, 2024 🙃) Amazing work from @lorenzlamm.bsky.social and colleagues 🤗 Special thanks to the community who jumped early on the boat, sharing feedback and training data to make MemBrain v2 a reality 🙏🏽
Met some locals during my trail run this weekend. They were not impressed by my pace.
Freddy would have been 80 today. What a great talent. www.youtube.com/watch?v=frdB...
Queen - Live Aid 1985 Full Concert
YouTube video by uploader.JP8
youtube.com
Jeremy Berg@jeremymberg.bsky.social · last mo.My quote of the day Is this the real life? Is this just fantasy? Caught in a landslide, no escape from reality Open your eyes, look up to the skies and see Freddy Mercury
François Jacob and Jacques Monod.
Nobel Prize@nobelprize.org · last mo.Which Nobel Prize laureate inspires you the most?
Our new paper with @ckellison.bsky.social. is finally out! We identify an ancient and widely conserved mechanism that promotes initiation of fiber polymerization in type IV pili and type II secretion systems.
β-strand addition within tip initiation complexes licenses assembly of diverse type IV filaments | PNAS
PilC/PilY1 proteins are tip-located adhesins of type IV pili (T4P) that are critical for T4P function in diverse behaviors including twitching moti...
pnas.org
Or me, if I were still at the bench in the lab 😬
chasingmicrobes@chasingmicrobes.bsky.social · last mo.Making biscuits this morning like...
