A small primer on the #NobelPrize awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi today. This prize was for combining two separate fields of immunology research - genetic research on IPEX and immunology research of regulatory T cells (#Tregs), with enormous impact on biology/medicine
Cecilia Domínguez Conde
@cdominguezconde.bsky.social
Human immunology & genomics 👩🏼🔬🧬 Group Leader at Human Technopole https://humantechnopole.it/en/research-groups/dominguez-conde-group/
30-year @esidsociety.bsky.social registry analysis of 30,628 patients' longitudinal datasets show results of robust epidemiological studies on natural courses including diagnosis, treatment, and survival, supporting newborn screening and future AI applications in IEI. rupress.org/jhi/article/...
Registration is open for ESID EHA SIOPE 2025 in Vienna (18-20 Nov)! Join us to explore the intersection of #immunology, #haematology, and #paediatriconcology. Excited to collaborate with colleagues across fields. 👉 Register: invt.io/1bxbhmwedno #Interplay2025
Join me at ESID-EHA-SIOPE 2025
Register today
invt.io
A must-read for anyone interested in human B cell physiology or pathology !
.@alneehus.bsky.social, @romberglab.bsky.social and @bloodgenes.bsky.social review how genetic variation impacts early B cell development, & discuss inherited rare variants & more common polymorphisms that predispose to B cell-related immune disorders & malignancies rupress.org/jhi/article/...
‼️ Kudos to Altea Gjurgjaj for leading this review article reflecting on how single-cell sequencing is pushing the boundaries of our knowledge on the drivers of autoimmune diseases 💡 🔗 onlinelibrary.wiley.com/doi/10.1002/...
Narrowing Down Key Players in Autoimmunity via Single‐Cell Multiomics
This review explores how single-cell sequencing and multiomics reveal cell states and communication networks involved in autoimmunity. We highlight insights into antigen specificity and autoreactive ....
onlinelibrary.wiley.com
Our review is out today in European Journal of Immunology! Together with @cdominguezconde.bsky.social, we explore how single-cell technologies are reshaping what we know about autoimmune diseases!🧬 @eurjimmunol.bsky.social onlinelibrary.wiley.com/doi/10.1002/...
🧬 Excited to announce the 2nd Euro Cancer DepMap Symposium bringing together leading minds in functional genomics, cancer vulnerabilities, AI, CRISPR and anti-cancer target discovery.📍Join us in Milan for cutting-edge science, open discussion & collaboration. #EuroDepMap #CancerResearch #CRISPR
2nd European Cancer Dependency Map Symposium - Human Technopole
The 2nd European Cancer Dependency Map Symposium is a scientific event open to the national and international scientific community working in computational genomics, pharmacogenomics, and therapeutic ...
humantechnopole.it
🔬 Join us in Milan for the 2nd European Cancer Dependency Map Symposium #ECDM25! A key event for scientists in functional genomics & target discovery. Talks, panels, AI & poster sessions await. Register now 👉 humantechnopole.it/en/trainings...
Thrilled that Sir Mel Greaves will be our next speaker for the @humantechnopole.bsky.social External Seminar Series on June 5th. Thanks to Andrea Sottoriva for hosting! For external people wanting to join, please see: forms.office.com/e/dtD3NcRKMN.
Exciting milestone for #HumanImmunity with the very first full issue of @jhumimmunity.org out now, including the #IUIS update on inborn errors of immunity + resources for clinicians. rupress.org/jhi/issue/1/1 #OpenAccess #IEI 👏👏👏
Volume 1 Issue 1 | Journal of Human Immunity | Rockefeller University Press
Journal of Human Immunity (JHI) publishes papers that provide novel insights into the physiology and pathology of human immunity through the study of genetic defects and their phenocopies, including t...
rupress.org
Complete First Issue of Journal of Human Immunity is here! JHI is the official #OpenAccess journal of the International Alliance for Primary Immunodeficiency Societies #IAPIDS. Explore new research and the inaugural editorial from our EiC @casanovalab.bsky.social 👉 rupress.org/jhi/issue/1/1
🔴LIVE NOW! Watch the Live Streaming of “OPEN HT – A day dedicated to #lifesciences research”, with institutional representatives on the occasion of the 10th anniversary of the MIND Milano Innovation district. humantechnopole.it/en/trainings...
Open HT - Watch the Live Streaming - Human Technopole
On 5 May 2025 from 10.00 to 13.00, "OPEN HT – A day dedicated to life sciences research" will take place at the Auditorium of Palazzo Italia, organised by Human Technopole, with institutional represen...
humantechnopole.it
🧬 Today we celebrate Rare Disease Day to raise awareness on rare diseases and the urgent need to improve diagnostic and treatment options for patients 🧬 ➡️ Follow the link below to see what we are doing at @humantechnopole.bsky.social to drive progress in this key field of biomedical research 🔬👩🏼🔬👩🏼💻
👨👩👧👦 Over 30M people in Europe and 300M worldwide live with a rare disease. Despite their great overall number, patients are the orphans of health systems, often denied diagnosis and treatment. 🔬 At HT, we believe in the power of research to drive change. #RareDiseaseDay
📣📣Genomic data sharing: you don’t know what you’ve got (till it’s gone) www.nature.com/articles/s41... A comment @natrevgenet.bsky.social from @katholt.bsky.social and me
🔬🎤 As pre-announced a few days ago... please let us proudly present to you: 𝑴𝒊𝒄𝒓𝒐𝕊𝒑𝒍𝒊𝒕 - your ticket to imaging more, imaging more gentle, and/or imaging more efficient. 🔬 doi.org/10.1101/2025... Like ❤️, repost 🔂, and most importantly... please send feedback ✉️ our way! 🙏
Immagine you could image two cellular structures in the same fluorescent channel and still reliably get them separated afterwards… What would you do with this? Now… what would you do if that also worked with 4 structures at once? 👇 #MicroSplit #preview🧵