Yongling Lin

@yongling.bsky.social

Postdoctoral researcher in Cognitive Neuroscience, Social Cognition, and Decision-Making @UCL

🧠 What makes threat memories so hard to forget? 🐍😱 Using focused ultrasound we provide causal evidence that the human amygdala drives rapid threat learning 🐍⚡ and determines how resistant those memories become to subsequent extinction 🐍🚫 🆕📄 www.science.org/doi/10.1126/...

The human amygdala in threat learning and extinction

Ultrasonic neuromodulation of the human amygdala provides causal evidence for its role in forming persistent threat memories.

science.org

New study out today in Nature Comms: www.nature.com/articles/s41..., in which we set out to test whether ultrasound could influence the reward-related learning computations of the nucleus accumbens, building on decades of work on dopaminergic prediction error and reinforcement learning. And it did.

Non-invasive ultrasonic neuromodulation of the human nucleus accumbens impacts reward sensitivity - Nature Communications

This study shows that non-invasive ultrasound to the human nucleus accumbens can modulate deep brain activity and enhance reward-guided learning, offering a potential alternative to invasive neuromodu...

nature.com

🚨We believe this is a major step forward in how we study hippocampus function in healthy humans. Using novel behavioral tasks, fMRI, RL & RNN modeling, and transcranial ultrasound stimulation (TUS), we demonstrate the causal role of hippocampus in relational structure learning.

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bioRxiv Neuroscience@biorxiv-neursci.bsky.social · 12mo ago

Causal necessity of human hippocampus for structure-based inference in learning https://www.biorxiv.org/content/10.1101/2025.08.19.664920v1

We are super excited about the first human transcranial ultrasound study from our lab which is now on BiorXiv, showing the amygdala‘s role in processing ambiguous emotions and showing TUS changed resting-state connectivity and metabolite concentrations (GABA) in the amygdala - a huge team effort! 🥳🙏🏼

Johannes Algermissen@johalgermissen.bsky.social · 12mo ago

Very happy to share my first preprint from @oxexppsy.bsky.social @oxneuro.bsky.social ! We (me + co-first authors @lilweb.bsky.social @mirunarascu.bsky.social + PI @mkflugge.bsky.social + many others) used transcranial focused ultrasound stimulation (TUS/tFUS/LIFU) of the human amygdala ... (1/15)

Thrilled to be a co-author on this amazing work published in Nature! Grateful to be part of such a fantastic team @mkwittmann.bsky.social.

Marco K Wittmann@mkwittmann.bsky.social · last yr.

New paper from our lab now in @nature.com . We show that our brains use basis functions or "building blocks" to navigate social interactions. Rather than tracking every individual separately, social information is compressed into patterns that can be flexibly combined. www.nature.com/articles/s41...

🚨New postdoc job alert!🚨 www.ucl.ac.uk/work-at-ucl/... ...we are looking for someone with an interest in computational psychiatry and/or naturalistic neuroimaging to work on a new ERC Advanced grant "The Neurocomputational Mechanisms of Anxiety Treatment Response (MECHANX)". (1/3)

UCL – University College London

UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).

ucl.ac.uk

Real pleasure to be part of this. State inference is clearly fundamental to learning and rl in particular so great to see this progress in terms of understanding how the hippocampus contributes. It will be great ti see if thus can explain some rl learning deficits in humans too.

Andrew MacAskill@macaskillaf.bsky.social · 2y ago

Huge congrats to @karyna-mi.bsky.social for her paper published today in Science! She found that the hippocampus is really important for a key strategy we use to make decisions called hidden state inference! 🧪 🧠https://www.science.org/doi/10.1126/science.adq5874 1/7