Wonderful 2026 group picnic with the amazing membrane protein scientists at the @cmd.ox.ac.uk!

Curious about how drugs are designed? Check out this seminar for non-scientists by Chris Tate, Group Leader in the LMB’s Structural Studies Division. He covers how drugs work and how researchers are working to design drugs better, faster and with fewer side effects. youtu.be/fOzwbmiKNKI

Drugs! How they work and how to design them. Seminar for non-scientists by Chris Tate

YouTube video by MRC Laboratory of Molecular Biology

youtu.be

@wheelerlab.org is talking about his effort to build a resource for protein dynamics (PDB for MD). MDRepo is a repository to store simulation data. This is really needed to push the needle in design, function and more. Please help make it successful by sharing your MD data. #ismb2026 🌐 mdrepo.org

A water molecule is crucial to maintaining the structure and transport activity of VcINDY! academic.oup.com/pnasnexus/ad... Fantastic collaboration by the groups of @danengw.bsky.social (NYUSoM) and @chrismulligan.bsky.social (Univ. of Kent)

Functional role of a structural water in the elevator domain of dicarboxylate transporter VcINDY

Abstract. The divalent anion sodium symporter (DASS) family mediates the uptake of Krebs cycle intermediates and sulfate, and influences adiposity, insulin

academic.oup.com

Thank you to @wehi-research.bsky.social for squeezing me in for a quick visit! Fascinating chats about targeting membrane proteins and structural biology for drug development!

Fun fact: Human NaCT/SLC13A5's mechanism for coupling sodium & substrate co-transport is distinct from its bacterial homolog VcINDY! A fascinating question to tease apart with @danengw.bsky.social and colleagues at NYU School of Medicine!

bioRxiv Biophysics@biorxiv-biophys.bsky.social · 3w ago

Structures of the human sodium-citrate cotransporter NaCT with and without substrates https://www.biorxiv.org/content/10.64898/2026.07.08.737274v1

Thank you @rosemaryjcater.bsky.social for a fantastic visit to UQ’s Institute for Molecular Bioscience!! Wonderful day chatting about the spectacular science in Brisbane, and squeezing in some time to visit the local fauna.

Kicking Arsenic to the Curb: a paper from the labs of Douglas Reese & Bill Clemons of @caltech.edu that describe cryo-EM structure of a bacterial metalloid pump & the mechanisms that could offer more insight into ridding environments of toxic metalloids. Read more here: buff.ly/dnyw7U1 #SBGrid

Kicking Arsenic to the Curb

This publication highlight is part of the SBGrid Communities Project focused on science education and demonstrating how structural biology…

buff.ly

Interested in joining our group in Oxford? We are looking for a PDRA with single particle Cryo-EM experience to help us figure out how sphingolipids are transported to the cell surface of Gram-negative bacteria. The deadline is 31st July. Informal enquires are welcome. Please share!

Take a look at the fantastic lineup of speakers we have assembled for the 2026 Kuo Symposium in Beijing! The workshop is already FULL, but symposium registration is still open, and early-bird rates are still available. See you in Beijing! www.bsc.org.cn/KuoSymposium...

Less than two weeks to register for the ion channel meeting. Please RT!

Laetitia Mony@laetitiamony.bsky.social · 2mo ago

Only 2.5 weeks left to register to the Ion Channel meeting that will take place in September in Sète (France)! Whether you want to connect with the #Ionchannel community or extend your summer on the Mediterrean sea (or both!), this conference is for you. Registration deadline July 3rd. Pls share!

Little one is obsessed with "Random Walks in Biology" (deceptively small as most biophysicists know) We should start with something easier, like partial differential equations?!

Structural basis of substrate recognition and allosteric inhibition in human B0AT2 www.biorxiv.org/content/10.64898/2026.06.16.732524v1 #cryoEM

How did animal senses evolve? Max Coyle et al. used choanoflagellates to uncover TRPW, ancient ion channels predating animal somatosensory receptors. TRPW links microbial prey ecology to evolution of receptor structure, sensory organelles, & multicellular processing. www.biorxiv.org/content/10.6...

Ready to start coding? Practical Python for Beginners begins 5 Oct 2026 and will help biochemists develop core Python skills for analysing and visualising complex biochemical data. https://ow.ly/FwKT50ZbyAM

🔬 We’ll be at the 6th NY Area #CryoEM Meeting on May 27, presenting recent developments in #CryoSPARC for Homogeneous Ab Initio Refinement and workflows for small proteins. bit.ly/4dYMUze We’re also proud to support the meeting as a sponsor — stop by our poster to learn more!

We have a late opening for postbac in my lab starting this summer. Please reshare, repost.

Anirban Banerjee@banirbn.bsky.social · last yr.

Interested in chemical mechanisms of membrane proteins ?We have an opening for postbac fellows. Please share and repost. Thanks ! Our research focuses on understanding the chemical and cellular mechanisms of integral membrane enzymes and transition metal transporters. bit.ly/42jWXYD. /n

The OpenBind consortium’s first release of experimental data marks a milestone in efforts to improve how artificial intelligence (AI) is used in drug discovery. Find out more ⬇️ https://www.ox.ac.uk/news/2026-05-12-openbind-releases-first-open-dataset-and-ai-model-for-drug-discovery

Proton-coupled alternating access in a versatile Spns drug efflux pump from Mycobacterium smegmatis https://www.biorxiv.org/content/10.64898/2026.05.09.724020v1

Today is SLC13A5 Epilepsy International Awareness Day! Continually impressed with all the work the TESS Research Foundation is doing to support patients and find treatments. www.tessresearch.org

It's great to see this important paper by Alexander Shtyrov out. If you hadn't read it yet on @biorxivpreprint.bsky.social, you can now do so in @pnas.org. 😀

cryoEM papers@cryoempapers.bsky.social · 3mo ago

Measurement of atomic scattering factors by cryoelectron microscopy pubmed.ncbi.nlm.nih.gov/42101996/ #cryoEM

Structural basis for the transport mechanism and cholesterol modulation of the human proline transporter pubmed.ncbi.nlm.nih.gov/42091899/ #cryoEM

New publication for SLC13A5 targeting compounds! Discovery of the BI chemical probe is out now in J. Med. Chem. Great work by Andrew Quigley, Liz Carpenter, and colleagues from Oxford's @cmd.ox.ac.uk, @boehringerglobal.bsky.social, and @thesgc.bsky.social pubs.acs.org/doi/10.1021/...

Discovery and Characterization of a Nonacidic Small-Molecule Inhibitor of the Sodium-Coupled Dicarboxylate Transporter NaCT

Citrate is a key metabolic intermediate that regulates both glycolysis and lipid metabolism. While most citrate is produced in mitochondria, some is imported from the bloodstream by the SLC13 family o...

pubs.acs.org

In another case of transporters doing more than you expect: SPNS2 is a glucose importer, in addition to its S1P export activity! Wonderful collaboration with Sarah Spiegel and colleagues at VCU School of Medicine, and the team at @cmd.ox.ac.uk www.nature.com/articles/s41...

Save the date: NYC-ISB26 Integrative Structural Biology symposium - Oct 8-9, 2026 Registration coming soon. Integrative structural biology is a powerful approach toward understanding biological macromolecular systems by bridging structural biology and biophysical methods. nysbc.org/nyc-isb26/

Starting 27 April 2026, our online Introduction to Statistics for the Life Sciences course helps you build confidence in data analysis and strengthen your research skills. Enrol today and study at your own pace: ow.ly/xuxT50YAvtN

Starting 27 April 2026, our online Introduction to Statistics for the Life Sciences course helps you build confidence in data analysis and strengthen your research skills. Enrol today and study at your own pace: https://ow.ly/xuxT50YAvtN

We’re hiring! Our group at CSHL has openings for postdoctoral fellows in structural biology with a focus on ion channels and receptors in neurotransmission and cancer immunology. Join and pursue unique, cross-disciplinary science to boost your career. jobrxiv.org/job/cold-spr...

Postdoctoral Position in Membrane Protein Biology & Ion Channel Physiology

Post a job in 3min, or find thousands of job offers like this one at jobRxiv!

jobrxiv.org

Are you excited by virology? Would you like to do a PhD? Three fantastic opportunities are available to do joint PhDs between @cvrinfo.bsky.social and @pirbrightinst.bsky.social Details in the thread below - please share! Deadline 8th May 2026, fully funded for UK Home students (1/4)

Register for the April 30 CodeBMB Webinar for - Scientists in the biosciences starting to code - Post-docs and graduate students who want to bring coding into their learning - Instructors involved in Biochemistry and Molecular Biology Education

PDB101: Register for the April 30 CodeBMB Webinar for Beginners

PDB-101: Training, Outreach, and Education portal of RCSB PDB

pdb101.rcsb.org