Another beautiful paper from Alessandro's @desimonelab.bsky.social lab!

Alessandro De Simone@desimonelab.bsky.social · 3w ago

How is proliferation modulated in regeneration for tissues to reach their right size? We found that, in zebrafish scales, proliferation is shut down by a moving front of osteoblast maturation. The front's dynamics scale with tissue size, ensuring proper osteoblast amplification. tinyurl.com/5e45twx3

Highly recommended! Susanna is an awesome mentor and scientist

Susanna Brantley@drsusanna.bsky.social · 3w ago

The Brantley Lab is hiring a Research Technician/Lab Manager! Looking for someone with a strong foundation in molecular biology, a team player, and excited about basic science. If you know someone who would be a great fit, please share! spartantalent.uncg.edu/postings/35995

I’m starting at the Hubrecht Institute at a new group leader from September. I will be hiring a PhD student through the PhD program ⬇️ If you, or anyone you know, is interested in theoretical biophysics, I will be very excited to hear from them — please send inquiries to my ISTA email for now :)

Hubrecht Institute@hubrechtinstitute.bsky.social · 2mo ago

Are you excited to redefine our understanding of molecules, cells, tissues and organisms? Then we are looking for you! Applications for the Hubrecht International PhD program (HIPP) are now open and will be accepted until September 15th. Read more here 👉 www.hubrecht.eu/hipp/

We would like to add one or two postdocs to our lab in the next couple of years. If you are close to finishing your PhD and interested in the science we do, feel free to reach out to discuss opportunities.

Happy to see Ashley's paper out @natphys.nature.com www.nature.com/articles/s41...

Decaying and expanding Erk gradients process memory of skeletal size during zebrafish fin regeneration

Nature Physics - Zebrafish can regenerate amputated fins back to their original size. It is now shown that gradients in extracellular signal-regulated kinase activity act as rulers during fin bone...

nature.com

Good luck @drsusanna.bsky.social! I know that you will do great. It was a treat to have you in lab and I might have learned from you more than you did from me. Stay in touch. #proudPI

Susanna Brantley@drsusanna.bsky.social · 2mo ago

It's official! The first members of the Brantley Lab have arrived at UNCG. 🪰 Excited to start this next chapter! Many thanks to @ditalialab.bsky.social for the training and mentorship that got me here. Stay tuned for beautiful microscopy and the adventure of teaching students how to use my code...

In 2018, I had the opportunity as a PhD student to write a review about chemical waves with @ditalialab.bsky.social Looking back, this was such a fun and valuable experience. If you’re curious to know more about how chemical waves regulate signaling in cells and embryos, check out our review! 🌊

Journal of Cell Biology@jcb.org · 3mo ago

@vdeneke.bsky.social and @ditalialab.bsky.social review how the spatiotemporal coordination of cellular functions across large distances is controlled by chemical waves. rupress.org/jcb/article/... 📕 Part of "Collective Behaviors and Self-Organization in Cells" rupress.org/jcb/collecti...

@vdeneke.bsky.social and @ditalialab.bsky.social review how the spatiotemporal coordination of cellular functions across large distances is controlled by chemical waves. rupress.org/jcb/article/... 📕 Part of "Collective Behaviors and Self-Organization in Cells" rupress.org/jcb/collecti...

Congrats to both of you! And totally deserved, @alisonkickuth.bsky.social!

Brugues Lab@brugueslab.bsky.social · 4mo ago

It was an honor to introduce @alisonkickuth.bsky.social during the Otto Hahn medal ceremony from the @maxplanck.de in recognition for her amazing PhD, where she discovered a new mechanism for unilateral cytokinesis (www.nature.com/articles/s41...)

@drsusanna.bsky.social paper is now out in its final form. Relative to the original preprint, we now show additional mutant data and a better way to display heat maps of gene activation. www.cell.com/current-biol...

Rapid transcriptional response to a dynamic morphogen by time integration

Using quantitative live imaging, Brantley et al. reveal that cells decode dynamic BMP signaling during dorsal patterning of the Drosophila embryo by integrating activity over time. These results advan...

cell.com

Be on the lookout for an exciting meeting that Matilde @matildegalli.bsky.social , Silvia @santoslab.bsky.social and I are organizing next year in Amsterdam. It will be a lot of fun. coming-soon.embo.org/w27-24

Nice new paper from Stas Shvartsman's group presenting an elegant mathematical model for the control of metamorphosis and testing it using Erk optogenetics. www.pnas.org/doi/10.1073/...

Optogenetic control of transition to metamorphosis | PNAS

System identification approaches are commonly used in engineering to infer simple yet predictive models of complex systems from their responses to ...

pnas.org

Happy to have contributed, together with former student Yitong Xu, to this paper. Read the thread below from @brugueslab.bsky.social for more details.

Brugues Lab@brugueslab.bsky.social · 8mo ago

Really excited to share our new paper in @nature.com! We uncovered how a physical instability of the cytoplasm coupled with the cell cycle drives cytoplasmic partitioning in early embryos #zebrafish #drosophila. Read more in this🧵 www.nature.com/articles/s41... 🤩 @poldresden.bsky.social @mpi-cbg.de

Excited to share Alison's @alisonkickuth.bsky.social paper from the lab out in @nature.com this week! We uncovered how a mechanical ratchet mechanism drives cytokinesis in early #zebrafish embryos. Read more in this thread 🧵 and at www.nature.com/articles/s41... 🤩 @poldresden.bsky.social @mpi-cbg.de

Congrats, Ale and lab. A big step forward with a lot of new and unexpected observations! These waves are fascinating indeed

Alessandro De Simone@desimonelab.bsky.social · 11mo ago

The lab’s first pre-print! We investigated how growth-inducing Erk activity waves are regulated in regenerating zebrafish scales. We discovered that Erk waves are followed by waves of expression of their own inhibitors, as predicted by excitable waves theory. tinyurl.com/26r2cmpj

Advanced grad students + postdocs: apply for the 2026 #kitpqbio summer course, "Physical Principles of Morphogenesis in Plants and Animals," at buff.ly/OXXMKEv. Apply by Feb. 1. Course directors Adrienne Roeder (Cornell) and Sebastian Streichan (UCSB)

@sushantbangru.bsky.social and @rdiegmiller.bsky.social new review on regeneration is out in Nature Reviews Molecular Cell Biology. A fun piece to write and another great collaboration with @kenposs.bsky.social.

Nature Reviews Molecular Cell Biology@natrevmcb.nature.com · 11mo ago

New Online! Signal control during tissue regeneration in adult animals

We are hiring!

Scott Soderling@scottsoderling.bsky.social · 12mo ago

Please repost!!: We are searching for new AI-Bio faculty at Duke to be part of a new Discovery AI center. Looking for faculty who focus on pushing boundaries in ML model development in a highly interactive environment. DEADLINE for applications- Nov 1st!! www.nature.com/naturecareer...

Just got back from a great visit to Vienna, spending time both at @impvienna.bsky.social and @istaresearch.bsky.social. Followed by a great visit to @embl.org. Amazing science, great and supportive colleagues and most notably incredible young trainees. It was so much fun to meet everyone.

Thanks, Paul! Means a lot coming from you, as your papers have been great inspiration for this study

Paul Francois@pfrancois.bsky.social · last yr.

Super impressive study by the group of Stefano di Talia on the segmentation of zebrafish notochord. There might even be a SNIC ! www.biorxiv.org/content/10.1...

🍽️🧬 How do diet and gut microbes shape fertility across generations? 🪱🔬 Our Laboratory at #InstitutPasteur is recruiting a PhD student to study epigenetic inheritance of fertility using C. elegans. Fully funded via the International PPU program. Apply now! 🌍 #PhDposition #Epigenetics #Inheritance

Institut Pasteur | 130 years of biomedical research@pasteur.fr · last yr.

🎓 Applications for Institut Pasteur's PhD programs open Sept 1-Oct 20, 2025 for October 2026 entry. Apply to up to 4 projects across 6 programs: PPU, PPU-IMAGINE @institutimagine.bsky.social, PPU-@ox.ac.uk, PPU-EID @upcite.bsky.social & more 🧬 Register now ✍️ www.pasteur.fr/en/education...

Tissue 'tectonic' collision is detrimental, but flies found two distinct solutions! Gratifying and grateful to be included in this collective effort, w/ Steffen Lemke, to crack the (or 'a') code of #cephalicfurrow, now out in @nature.com, all with @paveltomancak.bsky.social at the helm. (1/9)

Priyom's preprint is out on biorxiv. See below for a detailed thread. In a nutshell, she has discovered and characterized the oscillator that times notochord and spine segmentation in zebrafish. Turns out that there are uniform Erk oscillations across the entire tissue that act as timekeepers!

Priyom Adhyapok@priyomadhyapok.bsky.social · last yr.

Building a spine is no joke, but thankfully zebrafish have their own clocks to keep the pace. Excited to share our preprint on the role of biological oscillators in coordinating notochord development! (www.biorxiv.org/content/10.1...) Additional thread below

Building a spine is no joke, but thankfully zebrafish have their own clocks to keep the pace. Excited to share our preprint on the role of biological oscillators in coordinating notochord development! (www.biorxiv.org/content/10.1...) Additional thread below

Heartfelt obituary of Ben Shilo by Stas Shvartsman

Ben-Zion Shilo (1951–2025)

Ben-Zion Shilo, a distinguished Israeli geneticist (Figure 1), passed away this April at the age of 73 at his home in Rehovot. Benny, as he was known to his friends and colleagues around the world, ma...

cell.com

Just noticed a super nice preview of our paper by @ditalialab.bsky.social and Alexandra Hiestand. As always, good editorial experience with @cp-cellsystems.bsky.social www.cell.com/cell-systems...

Vascular scaling: A careful balancing act between proliferation and extrusion

How do vascular tissues grow with the rest of the developing organism postnatally? In this issue of Cell Systems, Pi et al. combine modeling with molecular biology to uncover how cell behaviors scale ...

cell.com

Yogesh Goyal@goyallab.bsky.social · last yr.

Excited to share our paper on deciphering the design & control principles of tissue scaling w/ Luisa Arispe! Amazing work by co-first authors Danielle Pi and Jonas Braun. We show *differentiated* endothelial cell proliferate in waves with ultrafast cell cycle time of ~5h www.cell.com/cell-systems...

Great dinner with current and former members of the lab, as well as current and former Duke members and friends of the lab. Great to catch up with @ceriweber.bsky.social ,Ben, @woonyunghur.bsky.social and share stories. Great @socdevbio.bsky.social meeting!

Excited to see @drsusanna.bsky.social 's work out as a preprint. Please read the thread below for some more information or check the paper out on biorxiv. www.biorxiv.org/content/10.1...

Susanna Brantley@drsusanna.bsky.social · last yr.

Excited to share the bulk of my postdocotoral work from the @ditalialab.bsky.social on how cells interpret dynamic morphogen signaling during development! Many thanks to our collaborators & coauthors @shelbyflies.bsky.social, Massimo Vergassola, Jacqueline Janssen, and Anna Chao.

A heartfelt thank you to @izfs.bsky.social for this incredible honor! I'm so grateful to receive an award in memory of Dr. Chi-Bin Chien, an inspiring scientist and pioneer in the zebrafish community 🐟💙

International Zebrafish Society@izfs.bsky.social · last yr.

We are excited to announce the winner of the Chi-Bin Chien Award, Dr. Victoria Deneke! See more about Dr. Deneke and the CBC Award here: www.izfs.org/news/congrat... @impvienna.bsky.social @vdeneke.bsky.social

Very much looking forward to this meeting!

Society for Developmental Biology@socdevbio.bsky.social · last yr.

🔈 We’re pleased to welcome Stefano Di Talia @ditalialab.bsky.social as an invited speaker at #ICDB2025! His work combines imaging and quantitative models to understand cell cycle coordination during embryonic development. 📊🧪