How good is MiniBWA, the successor to BWA? To test it, I ran MiniBWA on sequencing from 76 different species, comparing mapping speed, rate and accuracy with BWA MEM. In short, it's really good. If you map short reads, it's well worth your time. andrewcarroll.github.io/2026/06/30/t...
The Best of Both Worlds - Assessing MiniBWA
Recently, Heng Li released MiniBWA (GitHub) alongside a paper by Heng Li and Nils Homer describing the method (paper). MiniBWA builds on the approaches in Minimap2 (also by Heng Li), but falls back on...
andrewcarroll.github.io
![print_stan_file(bioassay_stan_file)
data {
int<lower=0> J;
vector[J] x;
array[J] int<lower=0> N;
array[J] int<lower=0, upper=N> y;
}
parameters {
real a;
real<lower=0> b;
}
model {
{a, b} ~ normal(0, 5);
y ~ binomial_logit(N, a + b * x);
}](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:trcknlehdydcvclaqrrhwlo4/bafkreif6uwmy3y4vqwseekgbnr3p3qcjjdtlag3ftesv6nilelc3wsjn54)
