Case Report @thelancet.bsky.social ID Grand Rounds: Endocarditis of aortic/mitral valves and myocarditis due to syphilis! Discussion of cardiovascular syphilis history too Wasn't on my DDx for Cx neg IE! www.thelancet.com/journals/lan...
@idvilchez.bsky.social
late 60s no comorbodites, with P. aeruginosa left knee periprosthetic joint infection. Few years ago had first L knee PJI with P. aeruginosa treated with DAIR and 6 weeks cefepime. Seem like recurrent infection, what surgical approach would you consider
New study in @cidjournal.bsky.social from France looking at molds (no yeast/dimorphics) found in blood cultures. n=80 isolates from 2012-2022 2/3rds were Fusarium, 10% Lomentospora, 5% Trichoderma, 5% Mucorales, 5% Aspergillus 70% Hematologic malignancies academic.oup.com/cid/advance-...
do you think we should routinely test Enterobacterales for the presence of ESBL or just base or treatment on ceftriaxone Resistance? How would you treat this UTI with bacteremia (assuming is TMP-SMX qnd FQ resistant)
If you have a large volume of PD patients, and you don’t do this, you will see fungal peritonitis It’s a 1B from @ispd1.bsky.social www.nephjc.com/news/ispd202... I can’t imagine the replies which say you need not 🤦🏽♂️ Also came up on the pod: www.nephjc.com/freelyfilter...
I tend not to but understand if people do it. Once patients get fungal peritonitis the nephrologists tend to remove the catheter and put them on HD which can have a big impact on QoL.
I really didn’t know heteroresistance in staph aureus was also a thing. But the lab is supposed to report as R if mec A gene found. pmc.ncbi.nlm.nih.gov/articles/PMC...
Reversion From Methicillin Susceptibility to Methicillin Resistance in Staphylococcus aureus During Treatment of Bacteremia
Approximately 3% of Staphylococcus aureus strains that, according to results of conventional phenotypic methods, are highly susceptible to methicillin-like antibiotics also have polymerase chain react...
pmc.ncbi.nlm.nih.gov
how would you treat and ICD infection with lead and valvular vegetation that grew Staph aureus mecA gene positive per Biofire but Oxacillin susceptible per routine blood culture? Would you treat as MSSA with cefazolin or as MRSA with Vanco or Dapto ?
Its imperfect data. But its some data and it suggests benefit. 5% absolute reduction in the RCT. I consider this to be a fairly low risk, high reward intervention. Short courses of fluc are generally well tolerated and there is evidence of benefit that's better than many things we do in ID
I usually follow the kidney society guidelines for PD peritonitis, which does recommend it. There is some evidence to support its use, albeit not the highest quality: Cochrane Review: pmc.ncbi.nlm.nih.gov/articles/PMC... SR/MA: www.sciencedirect.com/science/arti...
The efficacy of fluconazole for anti-fungal prophylaxis in peritoneal dialysis patients: A systematic review and meta-analysis
La eficacia de fluconazol como estrategia profiláctica en los pacientes con enfermedad renal crónica (ERC) sometidos a diálisis peritoneal (DP) con ex…
sciencedirect.com
if you have a patient with peritoneal dialysis catheter related peritonitis and you decide to treat with PO and/or intraperitoneal antibiotics, do you routinely recommend fluconazole prophylaxis?
🆕 #Breakpoints Episode: Drs. @annegretemartson.bsky.social, Megan Wimmer, and Evan Clemens join me to discuss all things (Val)ganciclovir!!! #idsky #pharmsky #amssky @sidpharm.bsky.social 🎧 sidp.pinecast.co
Inaugural article in a new section in @cidjournal.bsky.social called “Clinical Dilemmas in Infectious Diseases” led by IDMedEd superstars Daniel Minter and Varun Phadke designed to teach clinical reasoning Rewriting the Script academic.oup.com/cid/advance-... #IDSky
Rewriting the Script
Natasha Spottiswoode, MD DPhil, Daniel J Minter, MD, Rachel Friedman-Moraco, MD; Rewriting the Script, Clinical Infectious Diseases, , ciae589, https://doi
academic.oup.com
#IDsky I’m currently going through my old twitter feed to find old posts I liked to find out who’s missing from 🦋 LBaddour Javier Villafuerte IDdocAdi Marc Scheetz German Esparza Jason Pogue Hemi Sulaiman Brad Spellberg Sumon Chakrabati Zain Chagla Jose Montoya Lance Burkhart Jake Scott Laura Marks
🆕🔥"Is Antibiotic De-Escalation Safe and Beneficial to Patients with Sepsis?" Our new article is out today: 👇 #IDSky #MedSky #PCCSky #ICUSky #emimcc #Ansky #EMSky #AMSSky #TxID #meded #Pharmsky #RXSky @unmc.bsky.social @unmccom.bsky.social ⬇️ bit.ly/4g7bGLE
Validate User
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2025 CDC Adult Immunization Schedule 💉 www.cdc.gov/vaccines/hcp/imz-schedules/adult-age.html #VaccinesWork #IDSky #MedSky #immunization
Amazing news! HHS has determined that clinical research is no longer required for donors with HIV to donate their kidneys and livers for transplantation in the United States! Thank you to all the HOPE in Action teams and all the advocates for our patients! www.federalregister.gov/documents/20...
Organ Procurement and Transplantation: Implementation of the HIV Organ Policy Equity (HOPE) Act
The Department of Health and Human Services (HHS) amends the regulations implementing the National Organ Transplant Act of 1984, as amended (NOTA), to remove clinical research and institutional review...
federalregister.gov
pubmed.ncbi.nlm.nih.gov/39492946/
Associations of HIV and prevalent type 2 diabetes mellitus in the context of obesity in South Africa - PubMed
We found sex-specific differences in the relationship between adiposity and diabetes prevalence by HIV serostatus in South Africa. Notably, females living with obesity and HIV had lower prevalence of ...
pubmed.ncbi.nlm.nih.gov
Biomaterials friends, does anyone have recommendations for where to get PTFE molds made? I’m looking to make a set for ISO 5833.
📢 Brand new ID faculty position just posted @fredhutch.bsky.social in Seattle. Join our ID group that studies infections in immunocompromised hosts. The Emerald city has great academics, phenomenal facilities, outstanding collaborators - all in amazing surroundings. apply.interfolio.com/159913
