Excited to share our newest #SingleCell work on human #AlcoholUseDisorder in #Amygdala out in @natcomms.nature.com Paper: tinyurl.com/3xh54ath Data: zenodo.org/records/1765... Code: github.com/mjgirgenti/A... #Neuroscience #AlcoholUseDisorder #SingleCell #Epigenomics #GeneRegulation

We're hiring! The Hoffman lab at Yale is recruiting for Post-Doctoral Associate and Post-Graduate Associate positions available immediately. Join us! www.hoffmanlab.net/jobs #zebrafish #zebrafishjobs

How does cortisol tune brain networks to form strong emotional memories? Excited to share new work led by amazing former RA Flory Huang w collabs Rajita Sinha and @toddc.bsky.social #neuroskyence www.science.org/doi/10.1126/...

Dynamic brain mechanisms supporting salient memories under cortisol

The stress-related hormone cortisol alters dynamic brain networks predicting memory and arousal to promote emotional memories.

science.org

Looking forward to your visit and talk!

Marija Kundakovic@kundakoviclab.bsky.social · 10mo ago

Excited to give a seminar & visit Yale Psychiatry Dept @yale.edu next Monday, December 15th! Please join us if you are around: "Leveraging mouse and human (epi)genomics to improve #WomensMentalHealth " Looking forward to it! Many thanks to @mattgirgenti.bsky.social for this kind invitation!

🚨 New paper alert from our lab @yaleschoolofmed.bsky.social ! We generated DNA methylation maps from 6 postmortem brain regions (amygdala + hippocampus subregions) in PTSD, MDD, and control donors — the largest dataset of its kind! 🧠✨ 📖 Read more: www.biologicalpsychiatryjournal.com/article/S000...

Mapping DNA methylation signatures to identify epigenetic variation across subcortical regions of the human PTSD brain

Post-traumatic stress disorder is a mental disorder that may occur in the aftermath of severe psychological trauma. Epigenetic changes in the brain may play a critical role in understanding the neurob...

biologicalpsychiatryjournal.com

The Snell lab is seeking a Postbaccalaureate researcher and Postdoctoral associate to join our team. More details here: www.snelllab.org/contact-2

A summary of NIH Director Jay Bhattacharya's comments during his visit to UAB today for a town hall style presentation: -Important for scientific work addressing our nation's health problems to be done in the same communities where those problems are concentrated

Our recent overview of human stem cell models for studying neuropsychiatric disorders (including their limitations and future directions) is now openly available @annualreviews.bsky.social of Neuroscience With the great @rebeccalevymdphd.bsky.social

Meet MapMyCells! This tool saves neuroscientists precious time by comparing their data to massive, high-quality reference datasets, including our whole mouse brain multi-omics atlas and the Seattle Alzheimer’s Disease Brain Cell Atlas. 🧠📈 portal.brain-map.org/atlases-and-... #studyBRAIN

Very proud of our new #SingleCell work on #PTSD and #MDD out in @nature.com today. Paper: www.nature.com/articles/s41... News and views: www.nature.com/articles/d41... Press: medicine.yale.edu/news-article... Data: doi.org/10.5281/zeno... Code: github.com/mjgirgenti/P...

Single-cell transcriptomic and chromatin dynamics of the human brain in PTSD - Nature

A comprehensive analysis of the cell-specific molecular regulatory mechanisms underlying post-traumatic stress disorder in the human prefrontal cortex.

nature.com

We recently celebrated our annual Neuroscience Retreat🧠👥 Thank you so much to everyone who came and made it such a memorable retreat full of science, collaboration, and community🤝🤗📸👇

Join us today at noon 🕛 for a seminar by @michael-e-ward.bsky.social, MD, PhD, from NIH/NINDS, on neuronal lysosomes in health and disease. Thank you to @yaleneuro.bsky.social's Shaul Yogev and @sugarrayy.bsky.social for hosting! We hope to see you there!

In a new @yale.edu study, researchers led by @mattgirgenti.bsky.social from #YalePsychiatry used a comprehensive multi-omic approach to analyze postmortem brain 🧠 genomics and investigate the molecular differences 🧬 in PTSD and major depressive disorder 🔍

A Multi-Omic Approach Implicates Novel Protein Dysregulation in Post-Traumatic Stress Disorder

Yale scientists, led by senior author Matthew Girgenti, PhD, assistant professor of psychiatry, established a brain multi-omic and multi-region analysis

medicine.yale.edu

Excited to share our latest study of the PTSD prefrontal cortex out @GenomeMedicine. rdcu.be/ejZ3T Our systems biology approach established a brain multi-omic, multi-region analysis comprising individuals with PTSD and MDD

Hot off the science presses! The largest map of the brain's wiring and activity to date is featured on the cover of @nature.com. 🧠📈 Check out 'Cortex in Context' at: www.nature.com/immersive/d4...

Obsessed with this photo I took of a California Condor at the Oregon Zoo looking out into the rain majestically 🌧️

Our latest study identifies a specific cell type and receptor essential for psilocybin’s long-lasting neural and behavioral effects 🍄🔬🧠🧪 Led by Ling-Xiao Shao and @ItsClaraLiao Funded by @NIH @NIMHgov 📄 Read in @nature.com - www.nature.com/articles/s41... 1/12

Psilocybin’s lasting action requires pyramidal cell types and 5-HT2A receptors - Nature

A pyramidal cell type and the 5-HT2A receptor in the medial frontal cortex have essential roles in psilocybin’s long-term drug action.

nature.com