Eileen Parkes
@eileenparkes.bsky.social
Assoc Prof Oxford MD PhD. Oncology, early phase trials, tumour microenvironment #womenInSTEM #immunology
Absolutely - Sarah Cooper nailed it www.facebook.com/reel/1330663...
facebook.com
Brent Toderian@brenttoderian.bsky.social · 2h ago“How much does it cost to become Prime Minister? That's the experiment Nigel Farage and Reform UK seem to be running, having received political donations of £72 million from two crypto billionaires.” Shouldn’t that be “how much does it cost to buy the Prime Ministership?”
Our Oesophagogastric Cancer Centre of Excellence aims to improve outcomes for oesophageal cancer. We're looking at: 💊 new drugs 🧬 better biomarkers 🩺 better surgery Find out more 👇 youtube.com/watch?v=Kgyk7XPKcB0&source_ve_path=OTY3MTQ&embeds_referring_euri=https%3A%2F%2Fwww.cancer.ox.ac.uk%2F
Oesophagogastric Cancer Centre of Excellence
YouTube video by Oxford Cancer
youtube.com
You can learn a lot about someone from the way they name a sequencing order 😂 Here are a few that caught our attention in the Plasmidsaurus order queue (shared with permission from the customers who submitted them 🙂).
Supremely excited to share our new paper in @natcellbio.nature.com With an updated genetic cGAMP reporter, we reveal that cGAS activation by DNA damage is a rare event, and that cGAS enrichment on intracellular structures cannot be taken as evidence of activation. www.nature.com/articles/s41...
A versatile cGAMP reporter reveals principles of cGAS activation by DNA damage and chromosome instability - Nature Cell Biology
Lebrec et al. present a FRET-based cGAS reporter and show that cGAS activation by genotoxic stress is rare and uncoupled from micronuclei. The study implicates R-loop structures and subtypes of chroma...
nature.com
If you’re letting AI do a review of a manuscript for you, just know that (A) it’s super obvious to anyone reading it, (B) it’s dishonest - as you’re explicitly instructed not to do so, and (C) it’s careless - because you’re uploading someone’s confidential material to an AI app.
A new wave of grant funders is turning to lotteries to break ties between proposals go.nature.com/4wNlgw1
When the best decision is no decision: the rise of randomization in grant funding
If reviewers can’t reliably tell the difference between top grant proposals, why should they pretend they can? A new wave of funders is turning to lotteries to break the tie.
go.nature.com
1/ Delighted to share our paper out today in Nature: ZFP36L2 orchestrates stress-adaptive plasticity in regeneration and cancer. We found the switch that lets differentiated cells rewind into stem cells — in gut repair, and in metastasis. 🧵 doi.org/10.1038/s415...
ZFP36L2 orchestrates stress-adaptive plasticity in regeneration and cancer - Nature
The RNA-binding protein ZFP36L2 mediates stress-adaptive plasticity in intestinal regeneration and colorectal cancer metastasis.
doi.org
Our lab’s latest research is now published at Cell Reports. Inhibitory TIGIT signaling is dependent on T cell receptor activation: Cell Reports www.cell.com/cell-reports...
Inhibitory TIGIT signaling is dependent on T cell receptor activation
Immune checkpoint receptors, such as TIGIT, act to restrain T cell responses, but their regulatory mechanisms are poorly understood. Zammit et al. discover that inhibitory TIGIT signaling requires bot...
cell.com
Doing a *very slow* run after a long time out with injury - thumbs up and smiles from other runners are incredible, what a great community ❤️
The wildfires in Suffolk are the reality of a fossil-fuelled climate emergency that is making our summers hotter and more extreme. If we have any chance of preventing the worst of the climate crisis, we need to keep fossil fuels in the ground.
Is it possible to have grant writing PTSD? i.e. a certain font size and spacing will set off feelings of dread....
Nice Surfers Against Sewage Post box topper just appeared at the end of Ramsay Road in Headington, Oxford. 😀 @headingtonnews.bsky.social #YarnBombing @sascampaigns.bsky.social
The best live show I have ever had the privilege of being at - rest in peace www.theguardian.com/music/2026/j...
Glen Hansard, Oscar-winning Irish singer-songwriter, dies aged 56 in motorcycle crash
Frontman of chart-topping band the Frames had huge success as the star of 2007 romantic drama Once
theguardian.com
35.4% of pts with very high risk died within 48 hours of surgery, and 77.2% of those changed to end-of-life/comfort care in that time. This is clearly nonbeneficial. We all (pts and relatives included) need to get better at deciding when *not* to operate. jamanetwork.com/journals/jam...
Nonbeneficial Emergency Surgery in Older Adults at Risk for Early Mortality
This cross-sectional study examines the incidence of and factors associated with early mortality among older adults undergoing emergency general surgery as a marker of nonbeneficial surgery.
jamanetwork.com
Be skeptical of OpenAI’s rogue hacker agent story | John Thickstun
Be skeptical of OpenAI’s rogue hacker agent story | John Thickstun
If OpenAI loudly proclaims how dangerous AI is, investors will hear how powerful it is. And who benefits from that?
theguardian.com
Don't forget that the EACR-Worldwide Cancer Research Collaboration Fellowships are a new initiative this year, and you could be one of the first fellows! Application deadline: 03 September 2026 Apply here: eacr.org/collaboratio...
1. We—@eduede.bsky.social, @mjcrockett.bsky.social, Kevin Gross, and I—have a new preprint on the arXiv today, based on ideas that emerged during an @sfiscience.bsky.social workshop in November 2024: The unintended consequences of large language models as a labor-augmenting technology in science.
The unintended consequences of large language models as a labor-augmenting technology in science
As a labor-augmenting technology, large language models (LLMs) have the potential to accelerate scientific activity across the research pipeline. But even if LLMs perform on par with human experts at ...
arxiv.org
Absolutely - AI will lie rather than not answer a question, a fatal flaw that means all scientists should not be using this for anything meaningful (never mind the stolen IP etc)
Adrian Liston@labliston.bsky.social · 2mo agoMe trying out AI, yet again: Me: How can I generate a tool to do X? AI: Commonly scientists do Y (citation) Me: Which figure shows this? AI: I can't actually read papers, it is the vibe Me: This paper shows the opposite AI: To clarify, it is the opposite Me: That is not clarification AI: I panicked
I spoke with a nurse who has worked at a Bronx Hospital for 39 years and is now being laid off, along with 11 other nurses, to be replaced by AI. www.theguardian.com/technology/2...
The New York nurses replaced by AI: ‘It should concern every patient who cares about quality of care’
The union for 12 nurses laid off by Montefiore hospital say company broke contract they recently won through a strike
theguardian.com
English politicians ignorance of the Good Friday Agreement was demonstrated abundantly in Brexit already
Natalie Bennett@nataliegreenpeer.bsky.social · 2mo agoReform: For the "you couldn't make it up" file. “It’s discriminatory to the other indigenous languages of the UK." bylinetimes.com/2026/07/13/r...
This @nature.com Q&A with Ryan Rising covers his own journey – and his work to help others – to get a PhD after being incarcerated. So easy to take for granted the raw power of higher education. As told to @virginiagewin.bsky.social www.nature.com/articles/d41...
I want to see a prison-to-PhD pipeline
Ryan Rising creates programmes that help people who have been incarcerated to access academic opportunities.
nature.com
If you're at #ECMTB26 (or wish you were), you might be interested in our modelling paper out today in Plos Comp Biol! In which talented (ex-)student Nic Fan develops a #Chaste agent-based model to describe vascular remodelling in tumour growth models! journals.plos.org/ploscompbiol...
Exploring the relationship between vascular remodelling and tumour growth using agent-based modelling
Author summary We have created an agent-based model (ABM) that accounts for mechanical interactions between tumour cells and associated vasculature. The model simulates vessel occlusion and pruning du...
journals.plos.org
Progress against cancer not shared by poorer countries, WHO report finds
Progress against cancer not shared by poorer countries, WHO report finds
‘Persistent’ inequities found to exist in access to prevention, diagnosis, treatment and care, annual global review says Remarkable scientific progress against cancer has changed very little for millions of patients globally, who face devastating physical, emotional and financial consequences after diagnosis, a new World Health Organization report has warned. One person in five will develop cancer, according to WHO estimates, and the disease will touch 92% of people, either through their own diagnosis or that of a close family member. Continue reading...
theguardian.com
Inattentive drivers have collided with me three times in recent years. One of these led to my injury, ruined my confidence and destroyed my bike. You bet I'm going to let the police know if I see any of them on their phones. www.telegraph.co.uk/cars/comment...
The last thing drivers need is cyclists snitching on us to the authorities
As well as scrutiny from inside and outside our cars, bicycle-mounted busybodies are policing minor infractions
telegraph.co.uk
How I survived the record Paris heatwave while seven months pregnant
How I survived the record Paris heatwave while seven months pregnant
It feels as if we are being abandoned to our fate by those in power, with further extreme heat expected next week
theguardian.com
