Anuj
@rnfr2d2.bsky.social
CryoEM | Anaerobic structural biology | Bioenergetics | CO2 fixation and energy conservation SYNMIKRO Marburg
Congratulations to the winners of best PhD talk @ #MAdLand2026 from right to left: @caeciliafkunz.bsky.social from @jandevries.bsky.social lab, who won @theplantjournal.bsky.social award 🌱 @thanahartmann.bsky.social from Schuller lab and @hannahlepper.bsky.social from @franzificht.bsky.social lab
So happy to see this paper finally out 🥳 it took only seven years after the first purification of archaeal peptidoglycan 🤣 Congrats to all the people involved 🥂🍾 And here is the story behind the paper: communities.springernature.com/posts/cracki...
Cracking the Archaeal Cell Wall: How a hydrolase overturned a 50-year-old paradigm
Using bioinformatics, biochemistry, NMR, as well as the newly characterized enzyme ArmA from methanogenic archaea, we revised the existing knowledge on archaeal peptidoglycan structure. At the same ti...
communities.springernature.com
Simonetta Gribaldo@sgribaldo.bsky.social · 3w agoInterested in #archaea, #methane, #cell-envelopes? New paper out @nature.com ! We discovered an enzyme that specifically cleaves the cell wall of methanogens, revealing a new chemical structure of archaeal peptidoglycan, 50 yrs after its first description www.nature.com/articles/s41... #MicroSky 🧵👇
A sad day. Ada's pioneering work on the ribosome changed how we understand one of the central machines of life. She is a remarkable example of curiosity and boldness in pursuing questions that seemed impossible. Her scientific courage and persistence has been an inspiration.
Prof. Ada Yonath, Nobel Laureate and a Model of Scientific Perseverance, Has Passed Away - Weizmann Wonder Wander - News, Features and Discoveries
From pursuing an impossible dream to uncovering one of the cell’s best-kept secrets and advancing the design of improved antibiotics
wis-wander.weizmann.ac.il
Powering methanogenesis from fatty acids by a twin-heme-mediated reverse redox-loop https://www.biorxiv.org/content/10.64898/2026.08.18.745454v1
One month left to apply!! 🧪 @biozentrum.unibas.ch seeks a group👩🔬 exploring molecular questions relevant to climate 🌍, including biogeochemical cycles (e.g., carbon, nitrogen) ♻️, bioenergetic energy conversion (e.g., photosynthesis, chemosynthesis) ☀️⚗️, and the adaptation to environmental change 🌊🌡️🦠🌾
Ben Engel@cellarchlab.com · 3mo agoSuper excited to launch this search for a new endowed professor at the @biozentrum.unibas.ch! Join us to build a research cluster in Climate Biophysics! 🌍🌊🌾🔬🧪 This is a unique opportunity to create a community in Basel🇨🇭working together on this timely topic! ⏳🌡️ Questions? Please reach out! 👩🔬👨🔬
PLEASE SHARE! New job openings in my lab @zmbp-tuebingen.bsky.social. We have a broad interest into the mechanistic basis of how molecular complexes are rewired during cellular development in plants and during invasion by pathogens. 🌱🍄🔬 See details below 👇 #PlantSciJobs
We currently have an opening for a PhD position in the lab. If you are interested in pursuing some serious structural biology of photosynthetic and chloroplast processes please apply. Prerequisite is previous experience in cryoEM and/or phototrophs. stellenangebote.uni-marburg.de/jobposting/2...
Doctoral and Postdoctoral Researcher Positions in the Cluster of Excellence ‘Microbes for Climate’
stellenangebote.uni-marburg.de
This story is now published in @natplants.nature.com ! 🎉🎩 Check out the final article here: nature.com/articles/s41477-026-02361-1 Very similar to the original bioRxiv preprint, with the addition of some cool polysome analysis (in the supplementals)! Thanks and congrats to everyone involved! 🙏
Chloroplast-encoded small subunit extensions reshape the Chlamydomonas chlororibosome - Nature Plants
Using in situ cryo-electron tomography, researchers found a unique ‘arm’ domain on the small subunit of Chlamydomonas chlororibosomes. This discovery suggests that chlororibosome structure is more evo...
nature.com
Florent Waltz@florentwaltz.bsky.social · 8mo agoLong in the making, but happy to present the Chlamydomonas chlororibosome! Cryo-ET🔬reveals a large new domain on the small subunit, built from multiple extensions in conserved ribosomal proteins. bioRxiv 📖: shorturl.at/q44tG This suggests greater chlororibosome diversity than expected! 1/n 🧵
Who's interested in time-resolved serial crystallography on [FeFe]-hydrogenase?? Check out Moritz' new preprint: www.biorxiv.org/content/10.6...
Nature research paper: Architecture of the 8 MDa Hdr–Vhu–Fwd super-assembly in class I methanogens go.nature.com/4h34dRD
Architecture of the 8 MDa Hdr–Vhu–Fwd super-assembly in class I methanogens - Nature
The structure of the Hdr–Vhu–Fwd super-assembly reveals a lineage-specific and modular 8 MDa complex with the ability to adapt to diverse anaerobic niches.
go.nature.com
Awesome work to determine the structure of a freakin 8MDa enzyme complex with over 600 FeS clusters! Sophia won the poster prize at the recent GRC C1 👏 www.nature.com/articles/s41...
Architecture of the 8 MDa Hdr–Vhu–Fwd super-assembly in class I methanogens - Nature
The structure of the Hdr–Vhu–Fwd super-assembly reveals a lineage-specific and modular 8 MDa complex with the ability to adapt to diverse anaerobic niches.
nature.com
ProLOEWE@proloewe.bsky.social · 3mo agoHuge discovery from Marburg: Prof. Schuller (@synmikro.bsky.social),doctoral stud. @sophia-pa.bsky.social+colleagues have resolved1️⃣of the🧬🔬largest enzymes. Published in Nature, the study shows how methanogenic archaea generate energy under extreme conditions, offering🆕insights into the🌎carbon cycle.
Mother of all electron-bifurcating complexes is here! Congratulations to Sophia @sophia-pa.bsky.social for discovering and determining the structure of this mega assembly! You put in so much effort to get this paper published. I am so happy and proud of you and your achievement!
Sophia Paul@sophia-pa.bsky.social · 3mo agoExcited to share my paper! 🥳 Today in #Nature we reveal an 8 MDa Hdr electron bifurcating super-assembly in class I methanogens that couples the first and last steps of hydrogenotrophic methanogenesis. A lineage-specific adaptation to anaerobic niches. www.nature.com/articles/s41...
1/ Happy to share our preprint! The Mtr complex catalyses the second-to-last step of the methanogenesis and is an essential bioenergetic machine in most methanogenic archaea. Anaerobic cryo-EM of Mtr reveals a nitrogenase-like metallocluster bound at its active site! www.biorxiv.org/content/10.6...
Check out this latest work from @gyanaprakash.bsky.social on the structure of an electron bifurcating/confurcating hydrogenase from cyanobacteria!
Gyana Prakash Mahapatra@gyanaprakash.bsky.social · 4mo agoExcited to share our new preprint! How does the cyanobacterial hydrogenase HoxEFUYH drive photosynthetic H₂ production? Using #cryoEM, biochemistry, FTIR and EPR spectroscopy, we reveal its molecular mechanism, including the basis of electron bifurcation/confurcation. www.biorxiv.org/content/10.6...
1/7 New preprint: we found that Chlamydomonas carries a giant and unexpectedly elaborate chloroplast RNA polymerase with 12 previously unknown subunits, overturning the idea that the complexity of this organellar enzyme emerged during plant terrestrialization! www.biorxiv.org/content/10.6...
The structure of a 2-MDa chloroplast RNA polymerase reveals unexpected evolutionary complexity
Transcription in chloroplasts depends on the Plastid-Encoded RNA polymerase (PEP), a bacterial-derived enzyme whose catalytic core remains encoded by the highly reduced genome inherited from the cyano...
biorxiv.org
I’m extremely grateful for the ERC Advanced Grant – with the awarded 2.5 Mio EUR, we will tackle how electrodynamics effects control the energy currents of life. 🎉 🎉 🎉 www.su.se/english/news...
ERC Advanced Grant to research on the processes that power life - Stockholms universitet
su.se
Excited to share our new preprint! 🧬❄️ by brilliant @mdreimann.bsky.social and great collaborators! Using cryo-ET&EM, we reveal archaeal chromatin in a near-native state: variable-beads-on-a-string fibers shaped by growth phase and histone composition #ArchaeaSky www.biorxiv.org/content/10.6...
Do you enjoy the thrill of discovery? Does this photo give you good vibes? Then you might be the right person to join our lab! Current projects range from chloroplast transcription to thylakoid membrane remodeling & we would be happy to welcome bright and motivated people at all career stages!
Very happy to share my first preprint from my PhD 🎉 doi.org/10.64898/202... We develop an αHL-based framework to engineer and quantify selective diffusion across synthetic membranes using controlled nanopore chemistry. 1/7
doi.org
Cool to see our recent paper among the "Editors' Highlights" in @natcomms.nature.com that "aim to showcase the 50 best papers recently published" 🥰 www.nature.com/collections/...
Check out our latest paper – today out in JACS - on proton gates in the antiporter modules of Complex I! So proud of my amazing lab – Sofia Badolato, Sarah Rossmann & Hyunho Kim – and thank you @kawresearch.bsky.social for long-term support of our work. pubs.acs.org/doi/10.1021/...
Molecular Principles of Gating Proton Transport in the Antiporter Modules of Respiratory Complex I
The respiratory Complex I is a highly intricate redox-driven proton pump that powers oxidative phosphorylation across all domains of life. Yet, despite major efforts, its long-range energy transductio...
pubs.acs.org
Endlich wieder Massephase! 🙏🏻 Hier der Presseartikel für unsere neue Publikation: www.uni-potsdam.de/de/nachricht... @unipotsdam.bsky.social @unimarburg.bsky.social @schullerjm.bsky.social @natcomms.nature.com
Biomasse aufbauen – Membrankomplex hilft Steinfresser-Mikroorganismen, Kohlendioxid umzuwandeln
Medieninformation 06-05-2026 / Nr. 035
uni-potsdam.de
Now online with @natcomms.nature.com 🤩 doi.org/10.1038/s414...
Sven T. Stripp@stripplab.bsky.social · 7mo agoCarbonic anhydrase catalyses the interconversion of CO2 and HCO3- and helps increasing the net-CO2 concentration inside cells. Why? CO2-reducing enzymes like RuBisCO are notoriously slow and ineffective. However, import of HCO3- is typically coupled to ATP consumption...
We just received funding for a 2yr postdoc position on cryoEM of fungal gpcrs. Official call will open soon. Contact me if you‘re interested!
Heinrich-Heine-Universität Düsseldorf@hhu.de · 6mo agoDer Biologe Dr. Florian Altegoer vom Institut für Mikrobiologie der Heinrich-Heine-Universität Düsseldorf (HHU) erhält einen mit 210.000 Euro dotierten „Exploration Grant“ der Boehringer Ingelheim Stiftung (BIS).
Across scales from cells🦠 to atoms⚛️ – We reveal how anaerobic #bacteria break down very stable aromatic compounds found e.g. in oil spills 🛢️ #Bioremediation #TeamTomo 🧪 🧶🧬 🔬 Awesome collab with Lena, Matthias, @schullerjm.bsky.social @rnfr2d2.bsky.social @tomaspascoa.bsky.social @tamb-o.bsky.social
Tomas Pascoa@tomaspascoa.bsky.social · 6mo ago1/ Excited to share our preprint! 🥳 Degradation of aromatic compounds, including BTEX pollutants, requires highly endergonic aromatic ring reduction. Using #cryoEM and in situ #cryoET, we show how BCRII couples electron bifurcation modules in one giant redox machine www.biorxiv.org/content/10.6...
Thanks for the fun collaboration into this fascinating “oil eating” biomachine. I learned a lot! 🧪 #TeamTomo
Anuj@rnfr2d2.bsky.social · 6mo agoHow do “LEGO-like” electron-bifurcating modules combine to drive degradation in BTEX-contaminated ecosystems? Check out our latest preprint, where we use cryo-EM and cryo-ET to reveal how the 1 MDa BCRII complex powers extremely endergonic aromatic ring reduction. www.biorxiv.org/content/10.6...
1/ Excited to share our preprint! 🥳 Degradation of aromatic compounds, including BTEX pollutants, requires highly endergonic aromatic ring reduction. Using #cryoEM and in situ #cryoET, we show how BCRII couples electron bifurcation modules in one giant redox machine www.biorxiv.org/content/10.6...
How do “LEGO-like” electron-bifurcating modules combine to drive degradation in BTEX-contaminated ecosystems? Check out our latest preprint, where we use cryo-EM and cryo-ET to reveal how the 1 MDa BCRII complex powers extremely endergonic aromatic ring reduction. www.biorxiv.org/content/10.6...
biorxiv.org
New preprint alert 🚨: Who actually drives methane production in anoxic sediments 🧬🔥? We point to a transcriptionally dominant 🦠 clade: VadinHA17. shorturl.at/Rijc0 @bledinadede.bsky.social @taylorpriest.bsky.social
biorxiv.org
