Female Malat1-/- mice demonstrated altered Th2 cytokine expression, evidenced by a reduction in IL-10+ Th2 cells in both lung and spleen, while male Malat1-/- mice did not, revealing Malat1 as a novel determinant of immune sexual dimorphism. Read more: ow.ly/RgN050XQCz8.
Malat1 regulates female Th2 cell cytokine expression through controlling early differentiation and response to IL-2
Abstract. Identifying cell intrinsic regulators of immune sexual dimorphism is critical for treatment of several immunopathologies. We show that Malat1 is
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