Now open - LOIs for the Investigators in the Pathogenesis of Infectious Disease (PATH) program. Deadline is July 16 @ 3pm ET. Faculty in US and Canada are eligible to apply Grant Amount: $505,000 over five years More information here: buff.ly/mBR4XST #bwfpath

BWF Announces the 2026 Investigators in the Pathogenesis of Infectious Disease www.bwfund.org/news/bwf-ann... #bwfpath

BWF Announces the 2026 Investigators in the Pathogenesis of Infectious Disease - Burroughs Wellcome Fund

DURHAM, N.C. – The Burroughs Wellcome Fund is pleased to announce the recipients of the 2026 Investigators in the Pathogenesis of Infectious Disease (PATH) awards, recognizing assistant…

bwfund.org

Postdoctoral Position (Please re-post) A funded postdoctoral position for a recent graduate to study aspects of Neisseria gonorrhoeae pathogenesis, antigenic variation, genetics, or physiology. Please contact Hank Seifert h-seifert@northwestern.edu #Microsky, #Microbiology, #MicrobialEvolution

Never thought our paper would be mentioned here... @grakoui.bsky.social @anuradhaiitb.bsky.social @jakechoby.bsky.social @plosbiology.org

David Weiss@dweisslab.bsky.social · 5mo ago

Bacteria in our BRAINS??! We observed translocation of bacteria from the gut to the brain via the vagus nerve. This occurred after high fat diet, or without dietary changes in mouse models of Alzheimer’s, Parkinson’s, and autism. journals.plos.org/plosbiology/...

Big thank you to @liuswrites.bsky.social for this wonderful piece about our study revealing bacterial translocation from the gut to the brain in settings of high-fat diet or in models of Alzheimer's, Parkinson's, and autism. www.the-scientist.com/a-high-fat-d...

A High-Fat Diet May Drive Gut Bacteria to the Brain in Mice

Researchers discovered that gut bacteria could travel to the brain via the vagus nerve in mice, offering clues to the gut-brain axis’ involvement in some neurological disorders.

the-scientist.com

Bacteria in our BRAINS??! We observed translocation of bacteria from the gut to the brain via the vagus nerve. This occurred after high fat diet, or without dietary changes in mouse models of Alzheimer’s, Parkinson’s, and autism. journals.plos.org/plosbiology/...

Translocation of bacteria from the gut to the brain in mice

Recent studies link gut dysbiosis to neurological disease, but the underlying mechanisms remain unclear. This study shows that a high-fat diet increases gut permeability and enables bacterial transloc...

journals.plos.org

#NatMicroPicks More than just pumps? 🦠💊 Bacterial efflux pumps not only block drug entry but also disrupt intracellular drug–target interactions by preventing repeated drug rebinding #MicroSky www.science.org/doi/10.1126/...

Efflux pumps control intracellular drug-target kinetics by limiting rebinding in bacteria

Efflux pumps disrupt antibiotic rebinding inside bacterial cells, amplifying multidrug resistance.

science.org

🚨 Postdoc Opportunity – Microbiota & Cancer Biology 🚨 (@LSU) Moreira Lab seeks for enthusiastic postdoc to study microbiota–host interactions in oncology, with focus on 16S rRNA analysis, in vivo. PhD in microbiology/molecular/cell bio/oncology. Competitive salary w/exc.benefits. DM, w/CV and 3refs.

We are hiring postdocs :)

Excited to announce the upcoming 2026 Microbial Toxins and Pathogenicity GRC and GRS meeting taking place July 12 - 17, 2026 at Waterville Valley in New Hampshire. This meeting will be chaired by yours truly and co-chaired by @sunnyshinlab.bsky.social www.grc.org/microbial-to...

We show how bacteria can adapt to B-lactam stress by increasing the copy number of "wimpy" beta-lactamases to overcome new drugs/B-lactamase inhibitors, without de novo evolution. This threatens the beta-lactam dominated antibiotic pipeline. Congrats @jakechoby.bsky.social and team! rdcu.be/euijW

Copy number flexibility facilitates heteroresistance to increasing antibiotic pressure and threatens the beta-lactam pipeline

Nature Communications - Choby et al. show that dynamic increases in the copy number of preexisting β-lactamase genes in heteroresistance enables resistance of continua of cellular...

rdcu.be

@jakechoby.bsky.social is a rockstar - I encourage students/postdocs looking for an amazing mentor and excited to investigate a new frontier in antibiotic resistance to join Jake at UNC to study heteroresistance and defeat superbugs! Congrats, Jake and team on this exciting paper.

Jake Choby@jakechoby.bsky.social · last yr.

Excited to share the work with @dweisslab.bsky.social‬ and great collaborators on how gene amplification generates dynamic heteroresistance to new beta-lactams, like cefiderocol. We hope drug developers will consider heteroresistance during antibiotic development rdcu.be/euijW

Alert! The abstract deadline for the Microbial Pathogenesis & Host Response meeting has been extended to July 7 meetings.cshl.edu/meetings.asp...

Microbial Pathogenesis & Host Response

Cold Spring Harbor Laboratory Meetings & Courses -- a private, non-profit institution with research programs in cancer, neuroscience, plant biology, genomics, bioinformatics.

meetings.cshl.edu

Bactericidal antibiotics release bacterial DNA that activates TLR9, while static antibiotics do not. This can profoundly impact treatment outcome. Should clinicians consider this when choosing antibiotics to prescribe? Amazing work by Julia Gross and collaboration with Iain Fraser! rdcu.be/d1Phk

Bactericidal antibiotic treatment induces damaging inflammation via TLR9 sensing of bacterial DNA

Nature Communications - The immunologic differences induced by bactericidal versus bacteriostatic antibiotics remain unclear. Gross et al. show that, in contrast to static antibiotics, cidal...

rdcu.be