1 in 5 Greek puppies with chronic kidney disease have advanced liver disease and it is the liver disease that is most linked to poor quality of life

New at The Lancet Public Health - Targeting alcohol use in high-risk population groups: a US microsimulation study of beverage-specific pricing policies www.thelancet.com/journals/lan... #alcohol #LiverSky #MedSky

Targeting alcohol use in high-risk population groups: a US microsimulation study of beverage-specific pricing policies

Disproportionate increases in retail prices for the cheapest beverages, beer and spirits, might lead to a greater decline in consumption among high-risk groups. Pricing policies could thus be used as ...

thelancet.com

More #efruxifermin data this time in #MASH F2/F3 fibrosis @ 96 weeks ✅ Efficacy w/ dose dependent response (sort of) and NITs consistent ↔️ not crazy about mITT though it is mentioned no paired bx= non responders ⬇️ dose dependent reduction in bone mineral density #liversky

BaladoCritique : club de lecture médical@baladocritique.bsky.social · last yr.

"Safety and efficacy of once-weekly efruxifermin versus placebo in metabolic dysfunction-associated steatohepatitis (HARMONY): 96-week results from a multicentre, randomised, double-blind, placebo-controlled, phase 2b trial. Publié ce jour dans @thelancet.com www.thelancet.com/journals/lan...

New hope for #liverhealth: FDA recently approved Wegovy as the 1st #GLP1 therapy for adults with serious #liverdisease. Research presented at TLM ‘24 demonstrated the groundbreaking treatment potential. Learn more: https://bit.ly/45phv4R

journals.lww.com/hepcomm/full...

Endohepatology: Current perspectives and future directions : Hepatology Communications

field known as endoscopic hepatology or “endohepatology.” This domain integrates endoscopic diagnostic and therapeutic techniques, particularly those which are endoscopic ultrasound–based, into hepato...

journals.lww.com

When did I start rounding?

🥾A reboot with endless pearls! #452 NAFLD/MASLD! Expand your NAFLD/MASLD knowledge! Expert guest @ebtapper.bsky.social shares his framework for approaching NAFLD/MASLD and the treatment tools he recommends including lifestyle modifications and medications. www.thecurbsiders.com

my take on procal: 1. zero role in ED, shouldn't be used to start ABX 2. CAN be super helpful in first 24 hr after ICU admit to help disprove sepsis in complex cases (eg aspiration pneumonitis or atelectasis masquerading as PNA). helps stop ABX & redirect. 3. not helpful in limiting ABX duration

REBEL EM@rebel-em.bsky.social · last yr.

📉 Does trending biomarkers help stop antibiotics sooner safely in sepsis? 👀 More here: https://wp.me/pdrP8b-5mL #FOAMed #EMIMCC #MedSky

🚨 High Yield Infographic Alert! Elevated PTT? Think bleeding history. 🟢 Non-bleeders: APS, contact factor deficiencies, heparin. 🔴 Bleeders: Hemophilias, vWD, factor VIII inhibitors. Not all prolonged PTTs mean bleeding risk. #MedEd #Hematology #FOAMed #ElevatedPTT #TheCurbsiders

Another piece of evidence about the role of anticoagulants in cirrhosis. Results of a multicenter effort. The cirroxaban study. @hospitalclinic.bsky.social @idibaps.bsky.social @jhepatology.bsky.social kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F...

Jaume Bosch No one, and I mean no one, made more seminal contributions to the measurement, interpretation & clinical applications of HVPG, the prognostic impact of CSPH and its rx. Truly in the pantheon of all time greatest hepatologists and a kind, generous person on top. RIP #liversky

Ask my kids what my goals are - though I am consistent, they will tell you the order is reversed

Elliot Tapper@ebtapper.bsky.social · last yr.

LIFE GOALS 1. Raise happy children 2. Be old dude at grand rounds who falls asleep

LIFE GOALS 1. Raise happy children 2. Be old dude at grand rounds who falls asleep

Daughter wearing a Jean jacket for our day trip to Canada

I am very sad. My mentor and friend, Jaume Bosch, just has passed away. Thanks for everything, I will miss you. I would always remember our last day together celebrating a journey we begin together @hospitalclinic.bsky.social @idibaps.bsky.social

doi:10.1001/jamanetworkopen.2025.19426

Wake up new cause of liver enzyme elevation just dropped

They are establishing upper limits of normal for ammonia in pets Thank you for your attention to this matter!

podcasts.apple.com/us/podcast/l... Gideon is the best of us. Truly infectious enthusiasm for hepatology 👇 management of pbc 👇 clinical philosophy 👇 how to build a research career

The Latest in PBC with Gideon Hirschfield

Podcast Episode · Liver Talks: The Liver Fellow Network Podcast · 06/17/2025 · 35m

podcasts.apple.com

Recently had @ebtapper.bsky.social on the Critical Care Scenarios podcast talking GI and this topic came up. icuscenarios.com/lightning-ro...

Cardiovascular risk estimates miss the mark in people with MASH Heart disease is the most important risk for patients with MASH but the commonly used risk equations just don’t work New paper in the red journal @amcollegegastro.bsky.social journals.lww.com/ajg/abstract...

Cardiovascular risk assessment tools are insufficient for... : Official journal of the American College of Gastroenterology | ACG

tudy sought to determine the accuracy of the FRS, PCE, and PREVENT in a real-world cohort of patients with MASLD. Methods: This analysis included US adults ≥ age 30 with MASLD in the TARGET-NASH st...

journals.lww.com

Dear FreelyFiltered I am a listener of the podcast. I listen for the humans. And their input. I think the AI podcast on the NephJC was a nice as a way for me to hear about a trial and trial discussion I would have missed but the info didnt stick for this adult learner @kidneyboy.bsky.social

Hepatic encephalopathy is horrible It can present as disorientation and coma. But often causes poor quality of life, falls, and other trauma We want to prevent it. How can we predict it?

🚨Interested in Hepatology?🧑‍⚕️ Join us tomorrow at 10:30AM PST/1:30PM EST for a Hepatology VMR with the chief of Hepatology at U Michigan, Dr.Tapper (@ebtapper.bsky.social ) ! ✨🩺 We hope to see you there! ➡️ clinicalproblemsolving.com/learn-live/ #MedSky#ClinicalReasoning #Hepatology #MedEd

DDAVP for bleeding with incisions. Meh pubmed.ncbi.nlm.nih.gov/3513867/

Big meetings should provide real-time translation for at least the conferences centerpieces - named lectures, presidential plenaries.

🚨Check out our new study in @jhepatology.bsky.social ❗️ Using natural language processing to identify >350,000 patients with #steatosis, we demonstrated that cause-specific mortality differs between #MASLD #MetALD and #ALD www.journal-of-hepatology.eu/article/S016...

Cause-specific mortality in patients with steatotic liver disease in the United States

Causes of death across steatotic liver disease (SLD) subtypes remain incompletely characterized in routine clinical practice. We aimed to quantify and compare cause-specific mortality in SLD.

journal-of-hepatology.eu

🚨 Hot off the press! Our study is the first to define meaningful score differences (MSDs) for PROMIS, CLDQ & SF-36 in CLD - key to making PROMs clinically actionable! 🔗 journals.lww.com/hepcomm/Full... #LiverSky #GastroSky @aasldnews.bsky.social

There are two articles in NEJM this year that say naltrexone is 'contraindicated for cirrhosis'. This saddens me. It is not supported by an evidence. Alcohol is 'contraindicated for cirrhosis'. That is supported by evidence

Hanna Blaney, MD, MPH@blaneymd.medsky.social · last yr.

An important message on naltrexone in patients with liver disease: ✅Naltrexone can help reduce alcohol use without harming the liver. 🚫Alcohol DOES harm the liver. We do not need any more barriers to treat patients with AUD➕ALD! @nejm.org @ebtapper.bsky.social www.nejm.org/doi/full/10....