Ed Hollox

@edhollox.bsky.social

Professor of Genetics at U of Leicester. Genome structural variation. "Anyone with gumption and a sharp mind will take the measure of two things: what's said and what's done." Views my own.

Please share: Abstract deadline approaching (June 15) for the 2026 Annual Symposium of the Society for Immune Polymorphism (Nov 2-4, Netherlands). Intimate community meeting on variation and evolution of immunity and immune genes. Exciting lineup of invited speakers. #MHC #HLA sip-sassenheim.org

SIP2026 poster with invited speakers

“Introgression from Neanderthals & Denisovans shaped modern human genomes. We integrated high-quality assemblies of 4 Papua New Guinea genomes with 94 of diverse ancestry to infer an introgressed structural variant map. Results underscore introgression as a major force in human adaptive evolution.”🧪

A global map for introgressed structural variation and selection in humans

Genetic introgression from Neanderthals and Denisovans shaped modern human genomes; however, introgressed structural variants (SVs ≥ 50 base pairs) remain challenging to discover. We integrated high-q...

science.org

There's growing unease that the UK's political consensus on support for R&D is fraying, and the rise of populism could break it altogether In our lead Research Fortnight story today, the new president of the Royal Society of Biology, Melanie Welham, warned “political buy-in could weaken” 🧵

Was lucky enough to see her as a visiting seminar speaker around 2010, and I incorporated a chunk of her work on hsp and "evolvability" in a undergrad lecture for a good few years after that.

Admirable Women@admirablewomen.bsky.social · 2mo ago

Molecular biologist & geneticist Susan Lindquist (b. #OTD in 1949) was a pioneer in studying protein folding. Her research demonstrated protein folding errors contribute heavily to neurodegenerative conditions like Alzheimer's & Parkinson's diseases. National Medal of Science in 2010. #WomenInSTEM

This colorful portrait captures pioneering American molecular biologist and geneticist Dr. Susan Lindquist (June 5, 1949 – October 27, 2016), a National Medal of Science recipient who revolutionized our understanding of protein folding, prions, and heat-shock proteins. Facing the camera with a warm, confident smile, her short brown hair frames an engaging, intellectual expression. She wears a structured, dark green textured blazer over a striking, light blue silk scarf patterned with vibrant illustrations of sliced limes, lemons, oranges, and cherries, accented by elegant gold hoop earrings.She stands directly in front of a white dry-erase board covered in hand-drawn, multicolored biochemical pathways and pathways tracking "sterol biosynthesis," "Erg3," "Ergosterol," and "Mutations Azoles" from her famous research into evolutionary adaptations and antifungal resistance using yeast models. The tight composition and bright ambient lighting emphasize a deeply intellectual, creative, and historic mood, celebrating one of the most influential scientific minds of the modern era.