Ed Hollox
@edhollox.bsky.social
Professor of Genetics at U of Leicester. Genome structural variation. "Anyone with gumption and a sharp mind will take the measure of two things: what's said and what's done." Views my own.
My take-away from #SMBE2026 after 3 days: biodiversity genome projects such as Darwin Tree of Life @ergabiodiv.bsky.social @vertebrategenomes.bsky.social et al are no longer promises, but are changing how we do molecular evolution. I hope biodiversity gene expression will be next 😎 .
One crumb of positivity is how the local Scottish press - free of Reach plc's slop that now is the state of almost all local English press - has held management at Dundee to account.
Situation continues to worsen at Dundee University No serious repercussions for Prof Iain Gillespie & gang Echoing the Global Financial Crisis, those responsible seem set to evade any serious civil or criminal proceedings www.thecourier.co.uk/fp/politics/...
A sad day. Amazing to think this tree was around long before the Norman Conquest. ‘Most famous tree in the world’: Sherwood Forest’s 1,000-year-old Major oak dies www.theguardian.com/environment/...
‘Most famous tree in the world’: Sherwood Forest’s 1,000-year-old Major oak dies
Nottinghamshire tree, one of Europe’s oldest and largest, fails to produce leaves after being stressed by series of hot, dry summers
theguardian.com
I am recruiting a PhD student (fully funded, 4yrs) to analyze modern 🧬 and ancient 🦴 genomic data from humans and domestic animals 🐑 Please share, I am happy to chat at #ICP2026 or #SMBE2026 this summer www.uu.se/en/about-uu/...
PhD student position in Population Genomics - Uppsala University
PhD student position in Population Genomics , Department of Organismal Biology, Uppsala University
uu.se
People. @ksamuk.bsky.social and others have made this argument before. There’s good software to do this right. Here’s the argument again: Invariant sites matter! They’re not in your standard vcf and many programs pretend they are anyway. academic.oup.com/gbe/article/...
A Recipe for a Good π. How to Properly Estimate Population Genetics Summary Statistics and Why we Should Systematically Report Them
Abstract. Many long-standing questions in population genomics can now be addressed through comparative analyses and by leveraging the vast amount of genomi
academic.oup.com
Please share: Abstract deadline approaching (June 15) for the 2026 Annual Symposium of the Society for Immune Polymorphism (Nov 2-4, Netherlands). Intimate community meeting on variation and evolution of immunity and immune genes. Exciting lineup of invited speakers. #MHC #HLA sip-sassenheim.org
In completely unrelated news, my dear institution is now a Microsoft Frontier University and we now have copilot with everything.
"Oh God," said Zaphod. He hadn't worked with this computer for long but had already learned to loathe it.
“Introgression from Neanderthals & Denisovans shaped modern human genomes. We integrated high-quality assemblies of 4 Papua New Guinea genomes with 94 of diverse ancestry to infer an introgressed structural variant map. Results underscore introgression as a major force in human adaptive evolution.”🧪
A global map for introgressed structural variation and selection in humans
Genetic introgression from Neanderthals and Denisovans shaped modern human genomes; however, introgressed structural variants (SVs ≥ 50 base pairs) remain challenging to discover. We integrated high-q...
science.org
This seems to be excellent, but I can only read the first paragraph because my instuttuion does not have a subscription. Would anyone, or @ent3c.bsky.social , be able to send me a copy please?
www.nature.com/articles/s41... Such an excellent explanation
There's growing unease that the UK's political consensus on support for R&D is fraying, and the rise of populism could break it altogether In our lead Research Fortnight story today, the new president of the Royal Society of Biology, Melanie Welham, warned “political buy-in could weaken” 🧵
In 2011, after the August riots, the CPS pressed for the most onerous sanctions for all riot offences. The Director of Public Prosecutions was Keir Starmer.
I don't know how Keir Starmer can wake up in the morning, see that pogroms have been taking place under his watch, that they are being fuelled by literal illegal activity on social media, and not make it his entire purpose to stop it. We know you're no politician, but are you not a lawyer?
There are still spaces available on our in-person Introduction to #CryoEM #training course! Join us to learn: - what samples are suitable for cryoEM - what results can be expected - and more 📆 Tues 7 July, 9:30-16:30, The University of Leicester Find out more: my.rsb.org.uk/item.php?eve...
A Fellow of the Royal Society inciting riots? "Just an opinion" I guess.
Ah whats Elon Musk FRS up to now, the little scamp!
Was lucky enough to see her as a visiting seminar speaker around 2010, and I incorporated a chunk of her work on hsp and "evolvability" in a undergrad lecture for a good few years after that.
Molecular biologist & geneticist Susan Lindquist (b. #OTD in 1949) was a pioneer in studying protein folding. Her research demonstrated protein folding errors contribute heavily to neurodegenerative conditions like Alzheimer's & Parkinson's diseases. National Medal of Science in 2010. #WomenInSTEM
At this point it's basically pathlogical. The site is once again being used to whip up race riots and people with responsibility for national security are on it merrily whistling away.
Lammy says he doesn't think the Govt should come off X because that's where a lot of people get their information. FFS.
Postdoctoral job announcement: come to Cambridge and work on population genetic modelling with environmental and ancient DNA, jointly with @gamzeandgursoy.bsky.social and me. Details at www.jobs.cam.ac.uk/job/55580/ - applications by June 16th.
Research Associate in Population Genetics Modelling and Environmental DNA (Fixed Term) - Job Opportunities - University of Cambridge
Research Associate in Population Genetics Modelling and Environmental DNA (Fixed Term) in the Department of Applied Mathematics and Theoretical Physics at the University of Cambridge.
jobs.cam.ac.uk
What a find - the house of Peter Firmin, the creator of bagpuss, which doubled for Emily’s shop, is for sale www.rightmove.co.uk/properties/8...
Shearer is now VC at Leeds...
Those paragraphs baldly describe £95M squandered by @uniofnottingham.bsky.social’s senior managers, *none* of whom were held to account; they slipped off to new jobs. The staff they left behind are being made redundant to pay for it. It’s sickening. (www.timeshighereducation.com/news/careers...)
Paying peer reviewers works. Expanded Fast & Fair experiment @biologyopen.bsky.social: • 5.5 vs 37.7 working days to decision with reviews • ~3 vs ~9 reviewer invitations per manuscript • no reduction in editor-assessed review quality • similar acceptance rates www.biorxiv.org/content/10.6...
What fraction of the human genome is essential for cellular viability? More precisely, how much of the genome is DISPENSABLE for the growth of a haploid cell line? Somewhere between 50 and 96% (nb. as expected). www.biorxiv.org/content/10.6...
"The objective is a world in which we are seamlessly shuttled from one managed (and, ideally, exploitable) activity to the next – with no break or chance to look around us – from cradle to grave. The death of the university will bring that world a step closer."
The British university is dying, and it seems that almost nobody cares. newleftreview.org/sidecar/post...
⛪ New episode out 📺 @dorianlynskey.bsky.social and @iandunt.bsky.social tell the fascinating story of evangelical Christianity and how it became the dominant American religion, influencing not just spiritual life but politics too. Listen / watch ➡️ linktr.ee/originstoryp...
Any response to this @royalsociety.org ? This is a cut to teaching STEM subjects. Goodbye practical classes, goodbye field trips...
Breaking: Government set to cut strategic priorities grant. The government is on the cusp of cutting public funding for higher education teaching, the head of Universities UK has told MPs, placing institutions under even more financial pressure. www.researchprofessionalnews.com/rr-news-uk-u...
Today I'm posting a new blog about an astonishing scientific own goal. Hundreds of papers have reported using a totally wrong antibody to investigate the tumor suppressor p16. This mistake has happened because scientists have muddled the names of two proteins. forbetterscience.com/2026/06/02/m...
Morris is famous for funding Candy Crush, bankrupting Derby County football club, and err... investing in an AI company. Of course he knows what's best for science and universities.
Peer-reviewed papers are ‘old hat science’, says millionaire investor. Candy Crush businessman Mel Morris says universities “must embrace AI” to transform into economic powerhouses. www.researchprofessionalnews.com/rr-news-uk-i...
Colossal Biosciences and thier deextinction bs are superb players of this game. Easy, exciting copy for journalists who lap it up.
A lot of journalism in the tech space is basically free advertising. If some CEO makes a wild claim that is transparently designed to boost their market valuation you don't have to report it. This is how scams like Theranos happened. How many times have we heard that AGI is 1-2 years away? It's hype