Elise Kerdoncuff

@ekerdoncuff.bsky.social

Postdoc in population genetics at Institut Pasteur, Paris, France. https://ekerdoncuff.github.io/

Two new chapters from my free online book in human genetics out this weekend! These complete Part 3 of the book, on human population structure and history: 3.3: Human prehistory [separate thread] 3.4: Ancient DNA: a genetic time capsule [this thread] web.stanford.edu/group/pritch...

An Owner's Guide to the Human Genome

An Owner's Guide to the Human Genome

web.stanford.edu

Jonathan Pritchard@jkpritch.bsky.social · 3y ago

I'm delighted to release the first half of my new textbook in human genetics: web.stanford.edu/group/pritch... "An Owner's Guide to the Human Genome: an introduction to human population genetics, variation and disease"

Work from my amazing undergrad @leyan-wang.bsky.social is just preprinted! TL;DR: If you worry that ARG methods might fail on unphased data due to phasing errors, you may not need to. Check it out & consider reposting to support a great young scientist!

Leyan Wang@leyan-wang.bsky.social · 8mo ago

We are excited to share our recent work on the surprising robustness of Ancestral Recombination Graph (ARG) inference tools to computational phasing errors, now available on BioRxiv: biorxiv.org/content/10.1.... This work is co-advised by @yundeng.bsky.social and Rasmus Nielsen. 1/7

SINGER, our ARG inference method, is finally published and freely available online: doi.org/10.1038/s415... It was a long journey – 16 months from initial submission to acceptance. Is it just me, or has peer review gotten more arduous lately? 4+ rounds of review isn't so unusual these days...

Robust and accurate Bayesian inference of genome-wide genealogies for hundreds of genomes - Nature Genetics

SINGER is a method for creating ancestral recombination graphs to understand the genealogical history of genomes. The method has increased speed, and thus scalability, without sacrificing accuracy.

doi.org

It’s been 25 years since the UCSC Genome Browser launched. Nature profiles how the website remains an essential tool for navigating the genome and understanding its structure, function, and clinical impact. #Academicsky 🧬 🧪

’We couldn’t live without it’: the UCSC Genome Browser turns 25

After a quarter of a century, the website remains an essential tool for navigating the genome and understanding its structure, function and clinical impact.

go.nature.com

A new analysis of Indian genomes helps untangle these groups’ complex evolutionary history, uncovering a 50,000-year history of genetic mixing and population bottlenecks that shaped genetic variation, health and disease in South Asia. news.berkeley.edu/2025/06/26/s...

Scientists complete the most thorough analysis yet of India's genetic diversity - Berkeley News

A comparison of more than 2,700 complete genomes from South Asians uncovers a wealth of ancient and recent diversity and genetic links to disease.

news.berkeley.edu

Why do Polynesians gave high risk of metabolic disease? Dang Liu tests the thrifty genotype vs population adaprive patterns (considering % Austronesian & Papuan ancestries), demographics (strong bottleneck in Eastern Polynesians!). Results: both!! BMI thrifty, HDL & others under drift & more!! 🤩

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Evolution instructors! I'm adding 'Make an evolution meme' to the extra credit opportunities in my class this semester. I know I've seen some great examples of student-generated memes on here - can you share some of your favorites so I can give them examples of what I'm looking for?