Finally, 3D #cryoEM structure of a nucleotide polymerizing #RNA that copies #RNA to #RNA: tC19z, evolved at @mrclmb.ac.uk 15 y ago! www.biorxiv.org/content/10.6... @szokoli.bsky.social Jason Hingey, Dan Haack, Vivian Wu Nick Spellmon @navtejtoor.bsky.social @hhmijanelia.bsky.social
Elise White
@elisew00.bsky.social
Biophysics PhD student in the Woodson Lab @ Johns Hopkins | NIH F31 Fellow | On a mission to learn the Hfq-RNA tango, and decode how tertiary structure motifs choreograph ribozyme folding.
New from @woodsonlab.bsky.social @tjiandarzacq.bsky.social and @nilswalterlab.bsky.social www.nature.com/articles/s41...
Exchange dynamics and kinetic control of gene regulation complexes - Nature Reviews Molecular Cell Biology
Recent evidence reveals how gene expression complexes form transient assemblies that continually exchange their subunits under kinetic control. This Perspective proposes that these dynamics form the b...
nature.com
Benasque RNA 2026 was easily the best meeting I’ve ever been to. Grateful for the connections I made & the collaborations that were started. Going home was bittersweet. 🧬⛰️
Super excited to be in Benasque for the 2026 Computational Approaches to RNA Structure and Function Workshop! Benasque is the most beautiful place I have ever seen 😍🧬
Congrats, Sarah!! Very well-deserved 👏👏
Congratulations to historian Richard Kagan, neuroscientist Ulrich Mueller, political scientist Vesla Weaver, and biophysicist Sarah Woodson on being elected to the American Academy of Arts and Sciences. hub.jhu.edu/2026/04/30/a...
Excited to share our new paper! This was a fun project, and I’m grateful to all who made it possible! 🧬😊
Our new paper is out! Using 19F NMR, we show that Hfq rewires the conformational dynamics of a model sRNA in a site-specific manner. Uridines at the rim undergo faster exchange (~100 μs) than those in the proximal pore (~300 μs). Congrats Elise! 🎉🎉 www.sciencedirect.com/science/arti...
🎉 We’re excited to officially kick off the ERC Synergy project, snoOPERA, with Anthony Henras, Brigitte Pertschy, and Roland Beckmann! 🎉 Bringing together labs across 3 European countries and the US, we aim to uncover hidden functions of snoRNPs in ribosome assembly. Go team! tinyurl.com/2e5r57b5
Congratulations to Anthony Henras, winner of the ERC Synergy 2025 grant!
Parmi les 66 projets sélectionnés par le Conseil européen de la recherche, Anthony Henras et l’équipe EukaRiBio (MCD-CBI) sont lauréat d’un des 13 projets du
tinyurl.com
Breathtaking views at Catoctin Mt yesterday ☀️🙌 Love this hike!
Beautiful day to hike Billy Goat Trail Section A! So worth the drive 😊☀️
Our recent #singlemolecule study on RNase J decay is out! Congrats, Yuan! 🎉🎉 www.sciencedirect.com/science/arti...
Metastable Folding of Bacillus subtilis glmS Ribozyme Modulates Turnover by RNase J1
Rapid turnover of glmS mRNA in Bacillus subtilis by 5′–3′ exoribonuclease RNase J is essential for feedback regulation of glucosamine-6-phosphate (Glc…
sciencedirect.com
The story of how multiple RBPs cooperate to repress translation is now out in @cp-cellreports.bsky.social by @marcopayr.bsky.social and in a great collaboration with @hennig-lab.bsky.social! www.cell.com/cell-reports...
Ever wondered how several individual RBPs cooperate to repress translation? Lead by @marcopayr.bsky.social and in great collaboration with @hennig-lab.bsky.social, we simultaneously tracked the binding of several proteins to single mRNA molecules in real-time! www.biorxiv.org/content/10.1...
I had a blast with these apple-solutely brilliant scientists on Saturday!
This bunch of RNA lovers knows how to unwind! Enjoying A-U-tumn and apple picking 🍎🍏
I’m so honored and thankful to have won a poster prize! I learned a lot this week from this lovely community. Thanks to the organizers for putting on another excellent meeting.
Strasbourg sights! Enjoying every moment of the 2025 Microbial RNA Meeting 😊🇫🇷
Off to Strasbourg for the 2025 Regulating with RNA in Bacteria and Archaea Meeting! ✈️🇫🇷
Congrats, Jorjethe and Yi-Lan! 👏👏
Our new paper is out in PNAS! We show that competition for binding to the Hfq matchmaker disfavors mismatched sRNA-mRNA combinations while allowing matched sRNA-mRNAs to form stable pairs. Kudos to Jorjethe Roca and Yi-Lan Chen for their fantastic work on this problem! doi.org/10.1073/pnas...
📢 Paper with @sattler-lab.bsky.social now published in @narjournal.bsky.social ! doi.org/10.1093/nar/... We combine #NMR, #SAXS, and #MD to construct conformational ensembles, showing that A-to-I hyper-editing leads to significant structural dynamics. MD simulations by @piompons.bsky.social
Unique conformational dynamics and protein recognition of A-to-I hyper-edited dsRNA
Abstract. Adenosine-to-inosine (A-to-I) editing is a highly abundant modification of double-stranded RNA (dsRNA) and plays an important role in posttranscr
doi.org
Congratulations to Wilson on your NAR #Breakthrough paper!
New #Breakthrough article from @Woodsonlab.bsky.social shows how the E.coli RNA DEAD-box helicase unfolds unstable RNAs to fuel ribosomal RNA remodeling and the search for the native, protein binding structure! #Ribosome #RNA #Helicase 👉 Full article: https://doi.org/10.1093/nar/gkaf104
There’s nothing like peaceful weekend lab sessions! • No distractions 😌 • I’m free to sing and dance 💃 • Unlimited access to instruments 🔬 • The lab is my oyster 🦪
Hello #RNA afficionados! We’re excited to join the science community on Bluesky!
Another lovely snow day @ JHU!! Makes for a cozy morning break from experiments ☕️❄️
Absolutely gorgeous RNA-only complexes! I’ve never seen anything like these 🤯🤯
An intro, since I’m new to Bluesky: I’m a #biophysics PhD candidate in Dr. Sarah Woodson’s #RNA lab at @johnshopkins.bsky.social! I’m combining MD w/ NMR + confocal smFRET + TIRF to study the dynamics underlying Hfq-RNA complexes. (I also study ribozyme folding on the side!) Excited to connect 😊🧬