New preprint ! Poor sleep is correlated with accelerated aging. But is this relationship causal? We’re not so sure. www.medrxiv.org/content/10.6...

Amazing work by Siyuan Liu and co!! Sex differences in the brain don’t closely align with sex differences in behavior.

Armin Raznahan@bogglerapture.bsky.social · 3mo ago

Do humans show sex differences in brain activation? If so, are these task-specific or general — and do they relate to sex differences in brain anatomy and behavior? We dove deep into these questions in a new paper just out in Nature Communications | tinyurl.com/3rdrb524

Research Assistant Positions: The Affective and Clinical Neuroscience Lab (PI: Robin Nusslock) is seeking two research assistants to join a study investigating the impact of parental income on adolescent mental health and neuroimmune functioning. The start date would be ideally July/August 2026.

Use of brain age models frequently lead to wrong conclusions - unfortunately it is not easy to fix. Fortunately, there are better alternatives. @edvardg.bsky.social @fmrib-steve.bsky.social @didacvp.bsky.social @maxwellelliott.bsky.social @k.b.walhovd www.medrxiv.org/content/10.6...

Reconsidering Brain Age: Why Age-Prediction Models Fail as Measures of Brain Aging

Brain age models - machine-learning predictions of chronological age from brain imaging - are widely interpreted as markers of accelerated brain aging. Here we show that this interpretation cannot be ...

medrxiv.org

Aging reorganizes human large-scale brain networks, with consequences for cognition & dementia risk. We’ve now mapped brain network changes over a wide range of the mouse lifespan. The changes mirror key features of human aging, but not entirely New @pnas.org paper🧵 www.pnas.org/doi/10.1073/...

The first preprint from the lab is up! Are structural MRI correlates of substance use shared across substances, or are there unique associations? And do these reflect predispositional risk and/or possibly the effects of substance exposure? www.medrxiv.org/content/10.6... #neuroskyence

Brain Structure and Substance Use: Disentangling Risk, Exposure, and Drug-Specific Effects

Importance: Polysubstance use is common, but substance use associations with neuroimaging measures have largely been investigated within individual drug types. Whether effects are substance-specific o...

medrxiv.org

Are you interested in detecting brain changes in individuals with higher precision over shorter intervals? Check out our new paper in Nature Communications. With Randy Buckner, @jingnandu.bsky.social, and others. Link - doi.org/10.1038/s414...

Is schizophrenia associated with accelerated aging? In our new paper, we find evidence for consistently faster aging in schizophrenia, though not among unaffected siblings nor clinical high-risk youth doi.org/10.1017/S003...

#PenNLINC is recruiting a clinical coordinator / lab manager!!! Looking for someone who is good with both people + code, wants to learn to acquire + analyze imaging data. Alumni in this role have written 1st author papers + gone to top grad programs. Website: www.pennlinc.io Job: bit.ly/4ojvCir

neuroimaging | Satterthwaite Lab | UPenn

www.satterthwaitelab.com Homepage for Satterthwaite lab neuroimaging | neurodevelopment | adolescence | psychiatry | machine learning | network science

pennlinc.io

🔥🔥🧠PhD positions are open in my lab, studying brain development and neurodevelopmental disorders based on neuroimaging MRI scans. Due: Dec 1, 2025. If you are interested, please DM me.

My second first author paper of graduate school - Sex differences in response to violence: role of salience network expansion and connectivity on depression - is now published in Translational Psychiatry! rdcu.be/eLYg6

Sex differences in response to violence: role of salience network expansion and connectivity on depression

Translational Psychiatry - Sex differences in response to violence: role of salience network expansion and connectivity on depression

rdcu.be

Official job ad is up! careers.peopleclick.com/careerscp/cl...

Postdoctoral Researcher

Medical College of Wisconsin - Postdoctoral Researcher - Milwaukee WI 53201

careers.peopleclick.com

David Baranger@davidbaranger.bsky.social · 11mo ago

Excited to share that I am officially recruiting a postdoc to study the neurobiology of addiction! Looking for someone who would be excited to lead current projects in the lab and develop new directions in related areas. More info: bearlab.science/opportunities/

Our new paper is out now in Neuron! 🎉 With @vaibhavtripathi.bsky.social @maxwellelliott.bsky.social Joanna Ladopoulou, Wendy Sun, Mark Eldaief, and Randy Buckner Paper link: www.sciencedirect.com/science/arti...

Delighted to see the paper describing the Reproducible Brain Charts open data resource now out in @cp-neuron.bsky.social. Paper + link to data below; huge congrats to @goliashf.bsky.social @milhammichael.bsky.social and the whole RBC team. Lots of people (>2,500 downloads) are already using RBC!

Golia Shafiei@goliashf.bsky.social · 11mo ago

Excited to share that our work introducing the Reproducible Brain Charts (RBC) data resource is now published in Neuron!! 🎉 📚 Read the paper: authors.elsevier.com/c/1lpaF3BtfH... 🧠 Explore the RBC dataset: reprobrainchart.github.io

1/11 Excited to share our @Naturestudy led by @leonooi.bsky.social @csabaorban.bsky.social @shaoshiz.bsky.social AI performance is known to scale with logarithm of sample size (Kaplan 2020), but in many domains, sample size can be # participants or # measurements... doi.org/10.1038/s415...

Network analysis offers new insights into psychiatric symptoms. How can we use these tools to compare symptom patterns across groups? ⬇️🧵Thread below 🧵⬇️ doi.org/10.1017/s003...

Do you want to estimate brain aging from a single MRI scan? Check out our latest work in Nature Aging "DunedinPACNI estimates the longitudinal Pace of Aging from a single brain image to track health and disease"

Sex chromosome aneuploidies (varying X/Y-chrom dosage) can increase risk for psychopathology, but do these risks vary with age ? This matters for both clinical and mechanistic understanding. A fab recent trainee - Melissa Roybal - asked these questions in a new paper. This is what she found ... ⬇️

Telltale features visible in standard brain images can reveal how quickly a person is ageing https://go.nature.com/4kiNEPF

How fast is your brain ageing? Ordinary scans reveal the pace

Images hold clues to risk of dementia and various age-related diseases.

go.nature.com

Now published in @nataging.nature.com‬ ! We propose DunedinPACNI, a new measure of the rate of aging that can be derived from a single structural brain scan www.nature.com/articles/s43...

DunedinPACNI estimates the longitudinal Pace of Aging from a single brain image to track health and disease - Nature Aging

Differences in the Pace of Aging are important for many health outcomes but difficult to measure. Here the authors describe the Dunedin Pace of Aging Calculated from NeuroImaging measure, an approach ...

nature.com

New preprint!!! We can reliably detect brain changes in individuals in just a year by collecting several rapid 1-minute T1s at each time point - i.e. "cluster scanning". We discovered large individual differences, even in healthy adults t.co/oxD9EBdbvu

🚨 Brain Age vs Direct Models in Alzheimer’s disease (AD) 🚨 A thread 🧵 1/ Brain age is a powerful indicator of general brain health, trained on massive datasets. But does this translate to better prediction for specific outcomes, like AD? Preprint by @twktan.bsky.social : doi.org/10.1101/2024...

some people age faster than others – but how should we measure it? excited to share our preprint where we propose a new measure of the rate of biological aging that can be derived from a single structural brain scan posted to twitter a while ago...now on here too ! www.biorxiv.org/content/10.1...

An estimate of the longitudinal pace of aging from a single brain scan predicts dementia conversion, morbidity, and mortality

To understand how aging affects functional decline and increases disease risk, it is necessary to develop accurate and reliable measures of how fast a person is aging. Epigenetic clocks measure aging ...

biorxiv.org