How can we acquire new knowledge and skills on a daily basis while remaining the same person? I'm excited to share our new preprint led by @hyejinjadelee.bsky.social & Ally Dworetsky tackling this question, just in time for #OHBM2026: doi.org/10.64898/202... 🧵👇 #neuroskyence #PsychSciSky

Functional brain organization is stable within individuals across years

Brain regions exhibit dynamic yet highly coordinated activity patterns that form large-scale functional networks measurable through resting-state correlations. While their association with fluctuating...

doi.org

Openly shared implementation of TMS targeting is still rare, so we are pleased to make ours freely available for research use: github.com/ThomasYeoLab... Let us know if you have any issue running it!

Thomas Yeo@bttyeo.bsky.social · 2mo ago

Our TMS algorithm is now published in @imagingneurosci.bsky.social doi.org/10.1162/IMAG... If you are coming to @ohbmofficial.bsky.social @ohbmtrainees.bsky.social, come check out our poster about our open label trial. Poster number 1152 Monday, Jun 15 | 14:45-15:45 Tuesday, Jun 16 | 13:30-14:30

What matters most for childhood brain organization? We analyzed 649 variables. The answer: Socioeconomics (SES); with brain patterns pointing at sleep & stress as drivers. Even brain-IQ associations were better explained by SES. In Science today: www.science.org/doi/10.1126/...

Do humans show sex differences in brain activation? If so, are these task-specific or general — and do they relate to sex differences in brain anatomy and behavior? We dove deep into these questions in a new paper just out in Nature Communications | tinyurl.com/3rdrb524

Anti-science politicians and activists are spreading misinformation about science in Oregon. These misinformation campaigns have put the Oregon National Primate Research Center (ONPRC) at risk of closure. We’re asking you to use your voice. savescienceoregon.org/butter #standupforscience

We're hiring! FT research assistant @ UT Dallas Join our team to work on a longitudinal neuroimaging study of midlife brain aging. Strong opportunity for those interested in brain networks, aging, and Alzheimer’s disease risk. App. deadline now May 15. Details: jobs.utdallas.edu/postings/31680

Indiana University is in great financial health, according to a recent independent analysis. The report says administrative costs have grown significantly while instruction and faculty pay lagged. @weiss-a-woni.bsky.social Read more: www.ipm.org/news/2026-04...

"The differences between modern human and Neanderthal brains, as estimated from endocranial reconstructions, do not meaningfully exceed those among different modern human populations." www.pnas.org/doi/10.1073/...

Neanderthal brain and cognition reconsidered | PNAS

Neanderthal endocrania are different in shape, though slightly larger in size than modern humans on average. These shape differences have long been...

pnas.org

We're hiring! FT research assistant @ UT Dallas Join our team to work on a longitudinal neuroimaging study of midlife brain aging. Strong opportunity for those interested in brain networks, aging, and Alzheimer’s disease risk. App. deadline May 6. Details: jobs.utdallas.edu/postings/31680

Function & cytoarchitecture don't overlap ... they're orthogonal. Prefrontal cortex is plastered with chains of functional patches previously mostly known from face processing. Why multi-modal parcellations are wrong ... and other insights hidden by group-averaging of fMRI data. great explainer👇🏻

Evan Gordon@gordonneuro.bsky.social · 3mo ago

I always assumed that brain function had to line up with cytoarchitectonics. It turns out I was wrong. Human cortex, especially PFC, is tiled by chains of functional patches that subdivide and interlink architectonic areas into parallel processing streams. www.biorxiv.org/content/10.6...

Join this talented team! 🧠✨ Click on post below for details.

Gagan Wig@gaganwig.bsky.social · 4mo ago

We're hiring! FT research assistant @ UT Dallas Join our team to work on a longitudinal neuroimaging study of midlife brain aging. Strong opportunity for those interested in brain networks, aging, and Alzheimer’s disease risk. App. deadline May 6. Details: jobs.utdallas.edu/postings/31680

Come join our awesome team 😎

Gagan Wig@gaganwig.bsky.social · 4mo ago

We're hiring! FT research assistant @ UT Dallas Join our team to work on a longitudinal neuroimaging study of midlife brain aging. Strong opportunity for those interested in brain networks, aging, and Alzheimer’s disease risk. App. deadline May 6. Details: jobs.utdallas.edu/postings/31680

We're hiring! FT research assistant @ UT Dallas Join our team to work on a longitudinal neuroimaging study of midlife brain aging. Strong opportunity for those interested in brain networks, aging, and Alzheimer’s disease risk. App. deadline May 6. Details: jobs.utdallas.edu/postings/31680

𝐍𝐞𝐰 𝐉𝐨𝐢𝐧𝐭 𝐂𝐚𝐥𝐥 𝐟𝐨𝐫 𝐏𝐚𝐩𝐞𝐫𝐬 I am thrilled to announce an editorial collaboration between 𝐍𝐞𝐮𝐫𝐨𝐛𝐢𝐨𝐥𝐨𝐠𝐲 𝐨𝐟 𝐒𝐭𝐫𝐞𝐬𝐬 and 𝐍𝐞𝐮𝐫𝐨𝐬𝐜𝐢𝐞𝐧𝐜𝐞 𝐚𝐧𝐝 𝐁𝐢𝐨𝐛𝐞𝐡𝐚𝐯𝐢𝐨𝐫𝐚𝐥 𝐑𝐞𝐯𝐢𝐞𝐰𝐬. With @bartolomuccilab.bsky.social, I am co-editing a virtual special issue focused on: 𝘚𝘵𝘳𝘦𝘴𝘴-𝘪𝘯𝘥𝘶𝘤𝘦𝘥 𝘪𝘮𝘱𝘢𝘪𝘳𝘦𝘥 𝘩𝘦𝘢𝘭𝘵𝘩 𝘢𝘯𝘥 𝘢𝘤𝘤𝘦𝘭𝘦𝘳𝘢𝘵𝘦𝘥 𝘢𝘨𝘪𝘯𝘨

New paper in Imaging Neuroscience by Peiying Liu, Hanzhang Lu, et al: Non-invasive MRI of choroid plexus vascular function doi.org/10.1162/IMAG...

White matter pathways mediating dorsolateral prefrontal TMS therapy for depression New @natneuro.nature.com paper led by Caio Seguin, Robin Cash, and Andrew Zalesky. We map (indirect) pathways from DLPFC to SGC and link individual variation with response efficacy. www.nature.com/articles/s41...

Can't wait for our individual RFAs to open this summer? We now offer Small/Working Group Meeting grants on a rolling basis! If you have an idea for a meeting topic relevant to network interests, click the link below for more information!

Small/Working Group Meetings | Animal Models for the Social Dimensions of Health and Aging Research Network

The Research Network is pleased to offer grants for small/working group meetings with the aim of facilitating collaboration among Network members and affiliates and prospective Network members. These…

animalsocialaging-network.org

PNAS: Correspondence of large-scale functional brain network decline across aging mice and humans https://www.pnas.org/doi/abs/10.1073/pnas.2527522123?af=R

This image of home just came down from the Artemis II crew. Taken after their translunar injection burn, there are aurorae at top right and lower left, and zodiacal light at lower right. Credit: NASA/Reid Wiseman

Humans live many more years than mice, but our brain networks are aging much faster. Brain network decline follows a common trajectory across mouse and human adulthood, with features of network organization linked to more rapid decline. www.pnas.org/doi/10.1073/...

How do we define "good" fMRI data? Especially with resting state, there are circularity risks if we evaluate data quality as showing the networks we expect to see. Javier Gonzalez-Castillo (& me & others) developed pBOLD, a new metric that uses multi-echo info. www.biorxiv.org/content/10.6... 1/8

We’re excited to share a summary thread from the Wig Neuroimaging Lab on their latest PNAS publication. Explore the key findings below ⬇️

Gagan Wig@gaganwig.bsky.social · 4mo ago

Aging reorganizes human large-scale brain networks, with consequences for cognition & dementia risk. We’ve now mapped brain network changes over a wide range of the mouse lifespan. The changes mirror key features of human aging, but not entirely New @pnas.org paper🧵 www.pnas.org/doi/10.1073/...

"These findings point to a general process of functional dedifferentiation over adulthood, occurring at multiple levels of neural organization, from neurons to whole-brain networks."

Gagan Wig@gaganwig.bsky.social · 4mo ago

Aging reorganizes human large-scale brain networks, with consequences for cognition & dementia risk. We’ve now mapped brain network changes over a wide range of the mouse lifespan. The changes mirror key features of human aging, but not entirely New @pnas.org paper🧵 www.pnas.org/doi/10.1073/...

🎉Huge congratulations to McEwen fellow @ewinternelson.bsky.social and Dr. Gagan Wig of UT Dallas on their recent publication in PNAS on large-scale brain network decline across aging mice and humans and its translational relevance. Read the paper here: shorturl.at/gjau5

Correspondence of large-scale functional brain network decline across aging mice and humans | PNAS

Human aging is marked by progressive reorganization of large-scale functional brain networks; these brain network changes have been linked to cogni...

shorturl.at

The first part of my PhD research is out now in PNAS! See the thread below and stay tuned for my dissertation work, which builds on this cross-species model of brain network aging

Gagan Wig@gaganwig.bsky.social · 4mo ago

Aging reorganizes human large-scale brain networks, with consequences for cognition & dementia risk. We’ve now mapped brain network changes over a wide range of the mouse lifespan. The changes mirror key features of human aging, but not entirely New @pnas.org paper🧵 www.pnas.org/doi/10.1073/...

By analyzing brain activity throughout the lives of mice, Itamar Kahn, Gagan Wig, Ezra Winter-Nelson & team found that the rodent’s brain ages similarly to that of a human. Studying mice could therefore be a way to learn about how our brains decline as we grow old. @pnas.org tinyurl.com/38xwm5hv

Aging reorganizes human large-scale brain networks, with consequences for cognition & dementia risk. We’ve now mapped brain network changes over a wide range of the mouse lifespan. The changes mirror key features of human aging, but not entirely New @pnas.org paper🧵 www.pnas.org/doi/10.1073/...