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Evan DeTurk

@evandeturk.bsky.social

Incoming @MIT.edu history of science PhD student | via Cambridge HPS, @doudna-lab.bsky.social, Princeton/Bassler Lab | Demystifying biotech and biosecurity scifinow.substack.com 🧬🧪☣️

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Bel Esain@isabelesain.bsky.social · 4w ago

So excited to see our paper out in Science! Beyond grateful to my co-leads @petrskopintsev.bsky.social @evandeturk.bsky.social, all co-authors & collaborators, everyone in Doudna lab, and @innovativegenomics.bsky.social Being EsAIn in the DouDNA lab, it couldn't have been any other way ✨

Doudna Lab@doudna-lab.bsky.social · 4w ago

Our AI-guided design of RNA-guided nucleases is now out in @science.org 💻🧬 We used structure and evolutionary data to generate minimal, active and divergent gene editors! www.science.org/doi/10.1126/... Congrats to @petrskopintsev.bsky.social @isabelesain.bsky.social @evandeturk.bsky.social & team!

Petr Skopintsev@petrskopintsev.bsky.social · 4w ago

Proud to present our work, published today in @science.org! My deepest gratitude to @isabelesain.bsky.social, @evandeturk.bsky.social, Jennifer and our collaborators in the Doudna, Cate, Banfield, and Jacobsen labs, and the @innovativegenomics.bsky.social! I hope you enjoy reading it! ✨

Doudna Lab@doudna-lab.bsky.social · 4w ago

Our AI-guided design of RNA-guided nucleases is now out in @science.org 💻🧬 We used structure and evolutionary data to generate minimal, active and divergent gene editors! www.science.org/doi/10.1126/... Congrats to @petrskopintsev.bsky.social @isabelesain.bsky.social @evandeturk.bsky.social & team!

Innovative Genomics Institute@innovativegenomics.bsky.social · 4w ago

Out today in @science.org, Doudna lab researchers describe an #AI-assisted method for designing enhanced genome editors, testing close to 2000 in lab. Read more: innovativegenomics.org/news/ai-desi...

AI-Assisted Technique Allows Scientists to Design New, Functional Genome Editors Beyond What Can Be Found in Nature

AI-Assisted Technique Allows Scientists to Design New, Functional Genome Editors Beyond What Can Be Found in Nature - Innovative Genomics Institute (IGI)

innovativegenomics.org

Doudna Lab@doudna-lab.bsky.social · 4w ago

Our AI-guided design of RNA-guided nucleases is now out in @science.org 💻🧬 We used structure and evolutionary data to generate minimal, active and divergent gene editors! www.science.org/doi/10.1126/... Congrats to @petrskopintsev.bsky.social @isabelesain.bsky.social @evandeturk.bsky.social & team!

Evan DeTurk@evandeturk.bsky.social · 4w ago

It's out! Check out the D-LabSky thread below 👇 Pleasure working with and learning from @petrskopintsev.bsky.social @isabelesain.bsky.social and the whole team on this oen

Doudna Lab@doudna-lab.bsky.social · 4w ago

Our AI-guided design of RNA-guided nucleases is now out in @science.org 💻🧬 We used structure and evolutionary data to generate minimal, active and divergent gene editors! www.science.org/doi/10.1126/... Congrats to @petrskopintsev.bsky.social @isabelesain.bsky.social @evandeturk.bsky.social & team!

Evan DeTurk@evandeturk.bsky.social · 3mo ago

William Heath’s 1828 “Monster Soup” of microbes. I particularly love the crustacean-looking guys on the right! Fascinating convergence of the histories of biology and the city - would love to get urban studies people's thoughts on this.

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Evan DeTurk@evandeturk.bsky.social · 4mo ago

Been reading through lots of old Bulletin of the Atomic Scientists magazines recently for an ongoing project. Here are some of the coolest biology-related covers and illustrations I’ve found:

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Dimitri Drekonja, MD, MS@dimitridrekonja.bsky.social · 7mo ago

Alex from our time working together, while he was in nursing school. Later, he moved to ICU, working as a nurse to support critically ill Veterans. He had such a great attitude. We’d chat between patients about trying to get in a mountain bike ride together. Will never happen now

Alex Pretti from his early days working at the VA
Doudna Lab@doudna-lab.bsky.social · 7mo ago

New preprint 👉Doudna x Bryant x Jacobsen x Savage collaboration! Work led by @zehanzhou.bsky.social, I. Saffarian-Deemyad, @honglue.bsky.social, T. Weiss We dissect how stepwise DNA unwinding gates TnpB genome editing, revealing how unwound DNA states enhance cleavage www.biorxiv.org/content/10.6...

Stepwise DNA unwinding gates TnpB genome-editing activity

TnpB is a compact RNA-guided endonuclease and evolutionary ancestor of CRISPR-Cas12 that offers a promising platform for genome engineering. However, the genome-editing activity of TnpBs remains limit...

biorxiv.org

Walter Olson@walterolson.bsky.social · 7mo ago

Statement from Cato VP Clark Neily: Courts probably won't rule against the rendition. Yet Trump has chosen to bypass the constitutional provisions designed to cabin the president's powers in using force against other countries. And an indictment does not supply him with those powers.

Statement on Trump's Venezuela action by Cato Vice President for Legal Studies Clark Neily: * As a legal matter, any challenge by Nicolas Maduro to his capture last night and subsequent rendition to the United States would run headlong into precedents involving the prosecution of Manuel Noriega in the 1990s. Courts have already upheld the unilateral seizure, prosecution, and conviction of a foreign leader under materially similar circumstances, and given longstanding judicial deference in foreign-affairs cases, judges are unlikely to distinguish that line of authority in Maduro's case. That conclusion, however, should not obscure the deeper constitutional concern here, which is profound. The Constitution deliberately assigns to Congress—not the President—the power to decide when the United States will initiate hostilities against foreign sovereigns. That assignment includes the power to declare war and the related authority to issue letters of marque and reprisal to private entities, both of which reflect a constitutional judgment that decisions risking international conflict, retaliation, and escalation should not rest with a single executive actor. When a President unilaterally deploys military force abroad to seize a foreign head of state—effectively collapsing war powers, foreign relations, and criminal law enforcement into a single executive decision—the constitutional safeguards designed to cabin the use of force against other countries are bypassed entirely. That concern is not cured by the existence of a valid indictment. An indictment may (or may not) explain why a President wishes to act, but it cannot supply the constitutional authority to do so through military force without meaningful congressional engagement, let alone authorization.
Bel Esain@isabelesain.bsky.social · 8mo ago

First co-led work from the Doudna lab 🤜🤛 We designed minimal RNA-guided nucleases with AI, and even did Cryo-EM during an earthquake (!) Huge honor working with @petrskopintsev.bsky.social, @evandeturk.bsky.social, Jennifer Doudna and co-authors, everyone at D-Lab and @innovativegenomics.bsky.social

Doudna Lab@doudna-lab.bsky.social · 8mo ago

✨New preprint! 🧵1/4 Excited to share our work on AI-guided design of minimal RNA-guided nucleases. Amazing work by @petrskopintsev.bsky.social @isabelesain.bsky.social @evandeturk.bsky.social et al! Multi-lab collaboration @banfieldlab.bsky.social @jhdcate.bsky.social @jacobsenucla.bsky.social🧬 🔗👇

Evan DeTurk@evandeturk.bsky.social · 8mo ago

Excited to share our work designing genome editors with machine learning! 🧬💻 Huge thanks to @petrskopintsev.bsky.social @isabelesain.bsky.social @doudna-lab.bsky.social and all co-authors. Check out the thread for a summary of what we found 👇

Doudna Lab@doudna-lab.bsky.social · 8mo ago

✨New preprint! 🧵1/4 Excited to share our work on AI-guided design of minimal RNA-guided nucleases. Amazing work by @petrskopintsev.bsky.social @isabelesain.bsky.social @evandeturk.bsky.social et al! Multi-lab collaboration @banfieldlab.bsky.social @jhdcate.bsky.social @jacobsenucla.bsky.social🧬 🔗👇