And many thanks to @shaisrael.bsky.social and @mosheparnas.bsky.social for this thoughtful News & Views highlighting our work. www.nature.com/articles/s41...

Unforgettable forgotten memories - Nature Neuroscience

Memory is not always a faithful representation of past events; it can be lost, distorted or even fabricated. A new study provides insights into neural mechanisms that support the formation of true and...

nature.com

New preprint! www.biorxiv.org/content/10.6... Nearly a decade after starting the project, the first major results from our comparative connectomics work is online! Comparing the head direction circuits of the central complex in bees, ants and flies, recapitulating >300million years of evolution.

Distinct forms of dopamine transmission control locomotion and learning https://www.biorxiv.org/content/10.64898/2026.07.24.740623v1

Thank you Natalia Mesa at the @thetransmitter.bsky.social for highlighting our labs preprint on synaptic mechanisms of head direction learning!! 🪰🧭 Work from @markplitt.bsky.social in my lab in collaboration with the Jayaraman lab! www.thetransmitter.org/learning-and...

Unique learning mechanism drives navigation in fruit flies

The neuromodulator octopamine, the insect counterpart to norepinephrine, helps flies get their bearings in an unfamiliar environment.

thetransmitter.org

We, barnstedtlab.com, will be @ FENS Forum 2026. Check out the posters 👇👇 #fens2026

Oliver Barnstedt@obarnstedt.bsky.social · last mo.

14 years ago I went to FENS Forum in Barcelona to attend my very first scientific conference; fast-forward and I'm super excited to present to you part of my fantastic neuroscience research team in Göttingen. Do come by to say Hi and see what we've been up to recently! #fens2026

Really looking forward to our #fens2026 satellite symposium tomorrow!

Young PI Neuroscience Symposium'26@young-pi-neuro26.bsky.social · last mo.

Our @fens.org Satellite meeting is tomorrow! #FENS2026 Check out our updated program👇 youngpisymposium2026.com/program/ We are all super excited to have everyone joining! Safe travels everyone 🚅 ✈️ 🚲 See you in Barcelona 🔆😎

Story time friends... Ring attractor networks rely on fine-tuned symmetric connectivity. The fly head direction network has ring attractor dynamics but heterogeneous connectivity. How is this possible? 1/🧵 Link: www.biorxiv.org/content/10.6...

Congratulations, @salilbidaye.bsky.social and the whole team for another stellar work!

Salil Bidaye@salilbidaye.bsky.social · 3mo ago

Here’s our latest preprint on uncovering neural control of a coordinated walking pattern! doi.org/10.64898/202... (author-list jumbled, see pdf for corrected). Video shows the central paradigm in this study, we optogenetically induce walking in headless flies and sequentially reduce proprioception.

Object manipulation and affordance learning in Drosophila https://www.biorxiv.org/content/10.64898/2026.04.28.721021v1

How does an animal choose between exploring for a better food source and taking advantage of a known one? Our recent work in Current Biology demonstrates how recent feeding and metabolic state dynamically influence fly local search. bit.ly/3PfrIv3 #Science #Neurosky #Foraging #Drosophila

Flies beat their wings more than 200 times per second. How do proprioceptors rapidly sense and fine tune the wingstroke? @ellenlesser.bsky.social combined genetic tools with the connnectome to create an atlas of Drosophila wing proprioceptors. @elife.bsky.social elifesciences.org/articles/107...

Great work from Claire, Ravi, and the whole team– the initial lifelong continuous screen of behaving vertebrates provided a wealth of ideas on progression/staging of brain function across lifespan. Behavior is unmatched as a noninvasive quantitative readout of brain function (and, one that matters).

Zebrafish Rock!@zebrafishrock.bsky.social · 5mo ago

Youthful antics predict lifespan? Using machine learning & continuous recordings of #killifish behavior from adolescence until death, @brunetlab.bsky.social & @deisseroth.bsky.social find early-life behavior predicted future lifespan! Now published @science.org: www.science.org/doi/10.1126/... 🧪 1/2

Carolin Warnecke together with Hanna, Dennis, Bene & Kerstin from my lab show that re-exposure to reward diminishes multiple associated olfactory memories. We’re hiring 2 postdocs—DM/email me for details. #Postdoc #Hiring www.sciencedirect.com/science/arti...

Re-exposure to reward re-evaluates related memories

To adapt behavior in changing environments, animals must continuously re-evaluate previously learned associations. This flexibility of memory systems …

sciencedirect.com

Textbooks said neurons don’t burn fatty acids for energy🤔. Our study delivers the first in vivo demonstration that fatty acid oxidation in defined memory neurons fuels memory formation. Closing chapter of my PhD 🥳, out today in Nature Metabolism💥 @natmetabolism.nature.com

Neuronal fatty acid oxidation fuels memory after intensive learning in Drosophila - Nature Metabolism

Neurons are shown to use fatty acid β-oxidation as a fuel source for memory formation upon intensive learning in Drosophila, challenging the view that neurons are unable to use fatty acids for energy ...

nature.com

How do neural circuits generate the walking rhythm? Using connectome simulations, @sarahpugly.bsky.social found a minimal central pattern generator (CPG) that produces oscillations in leg motor neurons. Same circuit motif for each 🪰 leg. w @bingbrunton.bsky.social www.biorxiv.org/content/10.1...

Check out the newest Editors' (that would be me and Eunjoon Kim) Choice issue in Current Opinion in Neurobiology. Superbly guest edited by Stephen Liberles and @zknight.bsky.social >20 review articles on Interoception www.sciencedirect.com/special-issu...

Do flies feel pain? Spooky new preprint from our lab on the cells and circuits that mediate nociceptive behaviors in adult Drosophila, led by graduate student (and newly minted PhD!) @jonesjes.bsky.social. 🪰⚡👻🎃 www.biorxiv.org/content/10.1...

Exciting news for #drosophila #connectomics and #neuroscience enthusiasts: the Drosophila male central nervous system connectome is now live for exploration. Find out more at the landing page hosted by our Janelia FlyEM collaborators www.janelia.org/project-team....

Male CNS Connectome

A team of researchers has unveiled the complete connectome of a male fruit fly central nervous system —a seamless map of all the neurons in the brain and nerve cord of a single male fruit fly and the ...

janelia.org

What an exciting week!! Thanks to the Learning and Memory Conference and everyone 🙂🙂

Can a PhD hat 👩‍🎓be cooler than this one? Nope. Thanks to my 2nd home (Gerber lab) for making this wonderful journey full of learning and memory. I am wholeheartedly thankful to my mentors, collaborators, advisors, well wishers, LIN, colleagues, friends, my flies, and my family. Thank you 🙏 26/09/25

And here begins the 'LearnMamBo' era! Congratulations @obarnstedt.bsky.social as always!

Oliver Barnstedt@obarnstedt.bsky.social · 12mo ago

We are super excited that our project ***LearnMamBo*** Neuronal Dynamics of Learning and Memory in the Mammillary Body gets an #ercstartinggrant @erc.europa.eu – we will dissect the associated circuits supporting episodic memory – REACH OUT if interested in joining this project!

The first full central nervous system connectome dataset of an adult fly, with the most comprehensive annotation of sensory and motor neurons to date. A heroic effort with contributions from many groups, a product of the collaborative spirit of the Drosophila neuroscience community.

Matt Collie@mottcallie.bsky.social · last yr.

Happy Friday! The female adult fly brain-and-nerve-cord (BANC) connectome is now LIVE! Explore the data here: codex.flywire.ai?dataset=banc Check out the preprint here: doi.org/10.1101/2025...

🚨🚨My PhD work pre-print🚨🚨 Check it out 👇👇 'Avoidance engages dopaminergic punishment in Drosophila' It's a great collaborative enterprise and can't thank enough to my mentors and collaborators for the kindest efforts...fingers crossed 🤞🤞

bioRxiv Neuroscience@biorxiv-neursci.bsky.social · last yr.

Avoidance engages dopaminergic punishment in Drosophila https://www.biorxiv.org/content/10.1101/2025.07.07.663268v1

Our new paper out now in Science explores how neural activity in the lateral entorhinal cortex (LEC) *drifts* over time - and *jumps* at key boundaries - to help organize events in memory. 🔗 www.science.org/doi/10.1126/... Here's a quick summary of what we found 🧵👇

Event structure sculpts neural population dynamics in the lateral entorhinal cortex

Our experience of the world is a continuous stream of events that must be segmented and organized at multiple timescales. The neural mechanisms underlying this process remain unknown. In this work, we...

science.org

Edvard I Moser@edvardmoser.bsky.social · last yr.

Your brain doesn’t just passively track time ⏳ - it structures it. In @Science.org we show that activity in 🧠 memory circuits (LEC) drifts constantly, but makes sharp jumps at key moments, segmenting life into meaningful events. (1/2) 👉 www.science.org/doi/10.1126/...

How do brain circuits evolve? We started looking for some answers by using synapse-resolution cross-species comparative connectomics on an entire olfactory circuit 👇 bit.ly/44aVm9E

Excited to share our Science paper on HaloDA1.0-the first genetically encoded far-red dopamine sensor! 🥳It enables powerful multiplex imaging in neurons, brain slices, and live animals.🧠🔬 #GRABsensors #Dopamine www.science.org/doi/10.1126/...

In vivo multiplex imaging of dynamic neurochemical networks with designed far-red dopamine sensors

Dopamine (DA) plays a crucial role in a variety of brain functions through intricate interactions with other neuromodulators and intracellular signaling pathways. However, studying these complex netwo...

science.org

Nature research paper: Molecular gradients shape synaptic specificity of a visuomotor transformation https://go.nature.com/4jFNOQR

Molecular gradients shape synaptic specificity of a visuomotor transformation - Nature

Gradients of cell recognition molecules wire a sensorimotor interface in Drosophila.

go.nature.com

new preprint, led by @ellenlesser.bsky.social, on proprioceptive sensing of the Drosophila wing. tldr, there are a lot of proprioceptors out in the wing and they are wildly diverse and complex (eg, compared to the fly leg). just one example in this image...(1/4) www.biorxiv.org/content/10.1...

A projection from the lateral hypothalamus (LHA) to the pedunculopontine nucleus (PPN) prioritizes survival over other needs by triggering safety-directed movement @nkrauth.bsky.social @giachiblue.bsky.social @clemmensenc.bsky.social @olekiehn.bsky.social www.nature.com/articles/s41...

A hypothalamus–brainstem circuit governs the prioritization of safety over essential needs - Nature Neuroscience

Animals need to adapt behavior to balance survival with fulfillment of essential needs. Krauth et al. identify neurons in the lateral hypothalamus that, when activated, prioritize survival over other ...

nature.com

It is out! Read how you achieve 1.7 mm deep 3-photon imaging in prefrontal cortex with dendritic spine resolution over a week. www.nature.com/articles/s42...

Three-photon in vivo imaging of neurons and glia in the medial prefrontal cortex with sub-cellular resolution - Communications Biology

Three-photon in vivo imaging provides access to medial prefrontal cortex, hippocampus and spinal cord in mice at up to 1.7 mm depth of neurons, dendrites, spines, astrocytes and microglia.

nature.com