John Tuthill

@tuthill.bsky.social

Neuroscientist at University of Washington studying proprioception and motor control. Promoting the people and work in my lab (www.tuthill.casa). Also pursuing a snow fly side habit (www.snowflyproject.org).

When you start running, your breathing speeds up before your body needs the oxygen. Turns out flies do the same thing and @camellyc.bsky.social worked out the circuit that makes it happen. Check out our new preprint on how the nervous system coordinates breathing with movement.

Yichen Luo 骆奕辰@camellyc.bsky.social · 2d ago

1/8 Breathing seems automatic. But it's a finely tuned motor behavior that has to be controlled. In this preprint, I map the circuits that match a fly's respiration to the metabolic demands of flight and mitigate the risk of dehydration. 🧵🪰 www.biorxiv.org/content/10.6...

Probably the first scientific description of regeneration in crustaceans, by Réaumur 1712 The paper starts like this: Scholars are as wary of the marvellous as common people are ready to believe it. ... 🧵 1/3

drawing of regenerating crustacean leg by Arthur Monternier

Revised preprint on mitochondria in central brain of Drosophila now online: much new analysis + details of largest resource for analyzing neuronal mitochondria generated so far, with ~6M mitochondria, >20k neurons, >5k cell types. Much thanks to all coauthors, enjoy! www.biorxiv.org/content/10.1...

Connectomic Analysis of Mitochondria in the Central Brain of Drosophila

Mitochondria are integral to the metabolism and cell biology of a neuron. Electron microscopy images of fly brain volumes, taken for connectomics, can be analyzed for mitochondria as well as the cells...

biorxiv.org

We're hiring! NBIO is looking for a tenure-track Assistant Professor whose research & teaching will strengthen our department. 🧠 Deadline: 9/30/2026 Apply → apply.interfolio.com/187735 Please share with your network!

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John Tuthill@tuthill.bsky.social · last mo.

My department, Neurobiology and Biophysics at the University of Washington (nbio.uw.edu), is hiring a new tenure-track Assistant Professor, application deadline 09/30/26. It's a broad search — molecular to organismal, all of neuroscience/physiology/biophysics welcome. apply.interfolio.com/187735

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I am a neurodivergent neuroscientist. My bipolar brain brings struggle but it also helps me think off-the-map ideas. To help others who are similarly different, I co-founded the Neurodiversity Innovation Center for Excellence in Neuroscience (niceinneuro.org) with Leah Blankenship and Lila Kaye.

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Agentic coding is genuinely useful now, and there are some impressive reports of AI agents doing science. But how well and how reliably can they handle tasks scientists actually want to hand off, ones that bottleneck progress? How do we even measure that?? New paper🧵 arxiv.org/abs/2606.07718 1/10

A case study of evaluating AI agents on a neuroscience data-to-discovery pipeline

Agentic AI tools offer a promising path to automating software development bottlenecks in scientific research pipelines, particularly for stages that take domain experts days to months to build, where...

arxiv.org