De novo annotations on the AB genome are still in the pipeline, hopefully to be released in the next few months, but until then, these tracks can be downloaded if you need annotations for AB and don't want to do a liftoff/liftover yourself. Genome is here: genome.ucsc.edu/cgi-bin/hgTr...

Absolutely thrilled 💣 to share our preprint 🖨️: "Mapping active cis-regulatory elements from transcription initiation events”. www.biorxiv.org/content/10.6... We introduce nucCAGE and PRIME to identify active cis-regulatory elements (CREs) and disease-associated, non-coding variants.

Join us in Budapest in October! There is still time to register with an abstract. Talk and flash talk slots, a great speaker line up at an informal meeting on epigenetics, gene and genome regulation etc. in a beautiful city. shorturl.at/fOuCZ. For that to do list before the holidays!

In memory of Pierre Chambon (1931–2026): a visionary pioneer of modern molecular biology by Hinrich Gronemeyer in @embojournal.org link.springer.com/article/10.1...

In memory of Pierre Chambon (1931–2026): a visionary pioneer of modern molecular biology - The EMBO Journal

The EMBO Journal -

link.springer.com

Join is in Budapest in October! For the 6th time, all things epigenetics, gene and genome regulation and more. A fantastic opportunity to present, to talk to speakers and colleagues in a friendly, informal setting at a great location. Please note, travel grant deadline will expire soon.

Excessive paperwork and inefficient systems are sabotaging scientific progress. Really proud to be part of this global manifesto spearheaded by @kentimmis.bsky.social. We need action at all levels to tackle the root causes. Our analysis & proposals @microbiotech.bsky.social: doi.org/10.1111/1751...

Scientists' Warning to Humanity: Unnecessary Bureaucracy Is a Global Impediment to Productivity, Advancement of Human and Planetary Wellbeing, Science and Sustainability

Unnecessary bureaucracy is a global impediment to progress and productivity that increases stress and lowers workplace morale and motivation. In research it smothers creativity and innovation that ar....

doi.org

Help please! We need to do some large(ish) cell culture inhibiting E-cadherin with a monoclonal antibody. Does anyone have the DECMA-1 hybridoma cell line so we could purify our own antibody? or a similar monoclonal that would do the job. Any help greatly appreciated, just DM me. Please repost!

ICYMI… Huge congrats to Prof. David Grunwald @utah.edu for winning this year’s George Streisinger Award from IZFS! #RockOn 🐟 #zebrafish

International Zebrafish Society@izfs.bsky.social · 3mo ago

We are excited to announce the winner of the George Streissinger Award, David Grunwald! The Streissinger Award will be presented to Dr.Grunald at the 13th European Zebrafish Meeting in Vienna, Austria. Congratulations to David! #Zebrafish #IZFS #EZM #ZebrafishMeeting #IZFSAward

#RIP Pierre Chambon (1931-2026) via @alainberetz.bsky.social one of the last giants in biology: PARP, nuclear receptors, RNA Pol II, nucleosome, promoters, split genes

CRUK goes green [OA] news.cancerresearchuk.org/2026/04/01/w...

Why we won’t be funding open access publishing any more - Cancer Research UK - Cancer News

The open access movement was bold and promising, but ultimately disappointing. Now is the time to stop and call for a new way to make publishing work…

news.cancerresearchuk.org

Uni Sussex ditto

We are hiring 2 Postdoctoral fellows for our lab (www.mueller-lab.org): 1, Transcription control of metabolic adaptation in development (shorturl.at/oeG6U). 2, Semantic rules of developmental gene regulation (shorturl.at/KdHmJ) #jobs #transcription #zebrafish #zebrafishrock #IZFS

Research Fellow at University of Birmingham

Discover Research Fellow jobs and more in higher education on jobs.ac.uk. Apply for further details on the top job board.

shorturl.at

We are hiring 2 Postdoctoral fellows for our lab (www.mueller-lab.org): 1, Transcription control of metabolic adaptation in development (shorturl.at/oeG6U). 2, Semantic rules of developmental gene regulation (shorturl.at/KdHmJ) #jobs #transcription #zebrafish #zebrafishrock #IZFS

Research Fellow at University of Birmingham

Discover Research Fellow jobs and more in higher education on jobs.ac.uk. Apply for further details on the top job board.

shorturl.at

This is a fascinating paper that reveals defined and clear mechanism for a phenomenon that for some seemed unbelievable- the up regulation of genes paralogous to those with specific types of inactivating mutations. This is called transcriptional adaptation 1/ www.science.org/doi/10.1126/...

Mechanisms linking cytoplasmic decay of translation-defective mRNA to transcriptional adaptation

Transcriptional adaptation (TA) is a genetic robustness mechanism through which mutant messenger RNA (mRNA) decay induces sequence-dependent up-regulation of so-called adapting genes. How cytoplasmica...

science.org

AlphaGenome is out in @nature.com today along with model weights! 🧬 📄 Paper: www.nature.com/articles/s41... 💻 Weights: github.com/google-deepm... Getting here wasn’t a straight path. We discussed the story behind the model, paper & API in the following roundtable: youtu.be/V8lhUqKqzUc

Over the past weeks I have been reading the earliest papers on zebrafish development, and came to realize that in the “canonized" version of zebrafish history we neglect some important people pre-Streisinger. I will try to correct here the record. Let’s start with Edward C. Roosen-Runge. (1/7)

“Development, regulatory genomics & AI on April 22-24 www.stowers.org/events/stowe...

Stowers Research Conferences: Development, Regulatory Genomics & AI

Organized by Julia Zeitlinger, Ph.D., Neşet Özel, Ph.D., and Tatjana Sauka-Spengler, Ph.D.

stowers.org

2025 is a wrap! That’s the end of our coverage of all things #zebrafish for the year. We hope you have a safe and rejuvenating holiday season. Look out for us in the New Year! #RockOn

Open Team Leader position @embl.org to head & reshape our Genomics Core facility. Interested in providing & developing state-of-the art omics tech to a wide community? A very vibrant, dynamic place to work with fantastic colleagues. Closing Sept 30th embl.wd103.myworkdayjobs.com/en-US/EMBL/j...

Team Leader – Genomics Core Facility and Method Development

Are you ready to lead a cutting-edge Genomics Core facility while developing state of the art genomics methods? Join us at EMBL! We are seeking talented scientists to develop and lead a cutting-edge G...

embl.wd103.myworkdayjobs.com

Applications are now open 🚀for our fully funded Medical Research Council 4-year 🎓studentships 🎓 across our 3 partner institutions @unibirmingham.bsky.social @uniofleicester.bsky.social and @uniofnottingham.bsky.social See👉 more.bham.ac.uk/mrc-aim/phd-... to find out more and apply *by 9 Jan 2026*.

Together, these approaches create a uniquely powerful platform for exploring how transcription factors interpret the genome.” 📰 Read the full story: www.med.uio.no/ncmbm/englis... Congrats to the entire JASPAR community for driving this resource forward to shape the future of regulatory genomics!

JASPAR goes Deep Learning! - NCMBM - Norwegian Centre for Molecular Biosciences and Medicine

A new era for motif resourcesThe team behind JASPAR, led by Anthony Mathelier at NCMBM, has released the 11th update. JASPAR is built and maintained by an international consortium of research groups, ...

med.uio.no

Come join us in Heidelberg for the first German fish meeting 👩‍🔬👨‍🔬🧬🔬🐟🐠

Folks, it is finally out! Our paper on T2T assemblies of the zebrafish genome is on BioRxiv: www.biorxiv.org/content/10.1...

1. We start a major consortium programme funded by the sLoLa of BBSRC (shorturl.at/aUbnt) to decipher the semantic rules of enhancer arrangements driving regulator genes of development (shorturl.at/6qcjW).

🐟Meet the DANIO-ReCODE team!🐟 This week:Parth Bhatia and Prof @ferencmueller.bsky.social from @unibirmingham.bsky.social Parth´s research focuses on the annotation,characterisation and dynamics of cis-regulatory elements (CREs) in telencephalon injury 📢Stay tuned! #DANIO #MSCA @obog.bsky.social

PhD position (funded, competitive, shorturl.at/3zcmP, application details: shorturl.at/RDzd6) and postdoctoral fellow position (shorturl.at/UWtUV) are available in our lab. Topics: transcription regulation control of metabolism in development and upon toxic chemical exposures.

How does the interplay between metabolism control and gene regulation shape embryo development? at University of Birmingham on FindAPhD.com

PhD Project - How does the interplay between metabolism control and gene regulation shape embryo development? at University of Birmingham, listed on FindAPhD.com

shorturl.at

What is a promoter? And how does it work? We very happy to share our latest work trying to understand enhancer-promoter compatibility. I am very excited about the results of @blanka-majchrzycka.bsky.social, which changed the way I think about promoters www.biorxiv.org/content/10.1...

Enhancer-promoter compatibility is mediated by the promoter-proximal region

Gene promoters induce transcription in response to distal enhancers. How enhancers specifically activate their target promoter while bypassing other promoters remains unclear. Here, we find that the p...

biorxiv.org

If you've benefited from ZebrafishRock and its community, you can thank ZFIN. i.e. ZebrafishRock is actually Kevin searching ZFIN

Zebrafish Rock!@zebrafishrock.bsky.social · 10mo ago

Want an easy way to support your model organism databases? Cite them! Depending on the #zebrafish data you retrieve from ZFIN, you can show your support by using one of the formats below 🙏 🧪 #ZebrafishFunFacts

🏆 First Prize – DevBio Art Contest 🖼️
“A Model Meeting” by Karla Akari Garcia Inspired by The Quaker Meeting, this watercolor honors animal research models, from mouse to axolotl, that have advanced developmental biology 🎨 A tribute to science’s often unsung heroes. #DevBioArt

🐟DANIO-ReCODE MSCA DN🐟 As part of Consortium DCs training, PhDs attended a "Career Development Workshop" led by Amani Said, career coach. They took part in two sessions focused on how maximizing their PhD journey #DANIO #MSCA @obog.bsky.social @ec.europa.eu @cabd-upo-csic.bsky.social