This is so wrong-headed. You could not pay me to take a drug that was not tested in animals, and animal models remain absolutely essential for discovery research www.statnews.com/2025/05/19/a...

There is no replacement (yet) for animal models in medical research

The NIH is “reducing animal use in research.” But there is no replacement for animal models.

statnews.com

boehninglab@boehninglab.com · last yr.

This is extraordinarily dangerous and will slow academic biomedical research and drug development. A total ban is on the horizon. www.drugdiscoverytrends.com/nih-announce...

What Carole said -

@LaBonneLaB@labonnelab.bsky.social · last yr.

This is so wrong-headed. You could not pay me to take a drug that was not tested in animals, and animal models remain absolutely essential for discovery research www.statnews.com/2025/05/19/a...

x.com/XenopusNXR/s...

National Xenopus Resource on X: "https://t.co/q9x70xVVLs Please watch video and post a comment in support of use of animal models. They are seeking our input and if we don’t provide it then they will simply say well we didn’t hear anything" / X

https://t.co/q9x70xVVLs Please watch video and post a comment in support of use of animal models. They are seeking our input and if we don’t provide it then they will simply say well we didn’t hear anything

x.com

It is absolutely crazy to think we no longer need model organism research. www.sciencedirect.com/science/arti...

There is no replacement for animal models in medical research

sciencedirect.com

It is absolutely crazy to think we no longer need model organism research. - Carole Labonne www.sciencedirect.com/science/arti... #science #devbio #xenopus #frogs

here is the link: www.fda.gov/news-events/...

FDA-NIH Workshop: Reducing Animal Testing

The FDA is hosting a workshop on reducing animal testing. The workshop is open to current FDA and NIH employees.

fda.gov

This is mission CRITICAL. Please comment.

@LaBonneLaB@labonnelab.bsky.social · last yr.

Dear all, PLEASE add comments on the importance of model organism research at this link:

Legend!

Xenbase@xenbase.bsky.social · last yr.

Congratulations to Ray Keller, PhD for his election to the National Academy of Sciences. www.xenbase.org/xenbase/doNe... #science #devbio #xenops #frogs

Congratulations to Ray Keller, PhD for his election to the National Academy of Sciences. www.xenbase.org/xenbase/doNe... #science #devbio #xenops #frogs

Dr. Dominique Alfandari seeks requests for producing Xenopus antibodies. Fill out the form in the link to make your suggestions. www.xenbase.org/xenbase/doNe... #science #devbio #xenopus #frogs

The International Xenopus Board (IXB) Young Investigator Award recognizes an outstanding junior faculty member from any country making significant scientific achievements using Xenopus. Nominations due June 20, 2025. www.xenbase.org/xenbase/doNe... #science #devbio #xenopus #frogs

Thank you for the opportunity to speak about our work amongst so many cool talks! 🐸✨

Young Embryologist Network@yen-network.bsky.social · last yr.

Our last short talk of the day was Sarah Bowden @sarahbowden.bsky.social from @uni-freiburg.de on the role of Foxi1 for mucociliary progenitor and ectodermal specification in Xenopus

Excited for day one of the first @ epilepsyinst.bsky.social conference! If you ever wanted to know how tadpoles can help us understand DEE please come and chat at poster 2

Epilepsy Research Institute (@epilepsyinst.bsky.social)

Radically advancing epilepsy research.

epilepsyinst.bsky.social

Froggers post up!

Xenbase@xenbase.bsky.social · last yr.

Hello fellow froggers! Just over a week until the deadline for the Nikon Small World microscopy competition. Submit your images and show off the power of Xenopus! enter.nikonsmallworld.com #science #devbio #nikon #microscopy #xenopus #frogs

So incredibly happy that Ray Keller was elected to the AAAS! He's a pioneer of the cell biology of morphogenesis and of embryo mechanics, and a hero of mine. So grateful for his outstanding work. Even more grateful that he always took me seriously congrats Ray!!! www.amacad.org/new-members-...

New Academy Members

Elected in 2025

amacad.org

CRISPRi in frogs! cellandbioscience.biomedcentral.com/articles/10....

CRISPR/Cas-mediated mRNA knockdown in the embryos of Xenopus tropicalis - Cell & Bioscience

The Xenopus tropicalis (Western clawed frog) is an important amphibian model for genetics, developmental and regenerative biology, due to its diploid genetic background and short generation time. CRIS...

cellandbioscience.biomedcentral.com

Cool new work on metabolic activity in embryonic cell migration using #xenopus! journals.biologists.com/jcs/article/...

#xenopus and chickens coming together to parse Six1 targets and deafness risk genes! journals.biologists.com/dev/article/...

Check it out! #xenopus 🐸

Barriga Lab@eliasbarrigalab.bsky.social · last yr.

REPOSTING this here just to officially leave "the other place" Our work on the role of endogenous electric fields in guiding collective cell migration during #morphogenesis is out @naturematerials.bsky.social nature.com/articles/s41...

“We want to do something more interactive,” my graduate cell biology students said. “Like what?” I replied.

Cool new #xenopus paper on the contribution of sperm epigenetic marks on development! www.nature.com/articles/s41...

Does anyone know why Ensembl no longer have genome sequence of Xenopus laevis anymore??? Or am I missing something? Has this always been the case? @ensembl.bsky.social

Check it out! #xenopus to the rescue for functional genetics! 🧬 🐸

John Wallingford@jbwallingford.bsky.social · last yr.

So stoked to have a small part in this awesome paper @nature.com on human spina bifida with Jiny Ha, Sangwoo Kim, Joe Gleeson and others. Chanjae Lee did ALL the heavy lifting for the in vivo validations in my lab. this great work was ONLY possible thanks to the NIH! www.nature.com/articles/s41...

Check it out! 🤩🐸✨

Eva Hörmanseder@evahoermanseder.bsky.social · last yr.

Do you work with reprogrammed cells? Then look at our new paper! We asked: How well do reprogrammed cells differentiate into complete&functional tissues? We found that - some cell types form perfectly but others fail - reducing levels of one specific TF of the previous lineage can fix problems⬇️

Think you’re stressed? Check out this new work on inducing tissue strain coupled to live imaging 🐸✨ pubmed.ncbi.nlm.nih.gov/40059484/

Preprint Alert! Juyeon Hong in the lab has dissected the molecular organization of distal tips of vertebrate motile cilia. She even found a new compartment in the extreme distal tip marked by Ccdc78 and Ccdc33. Give it a read! @biorxiv-cellbio.bsky.social www.biorxiv.org/content/10.1...

Molecular organization of the distal tip of vertebrate motile cilia

The beating of cilia on multi-ciliated cells (MCCs) is essential for normal development and homeostasis in animals. Unlike basal bodies or axonemes, the distal tips of MCC cilia remain poorly defined....

biorxiv.org

Our Xenopus team in action! 🐸🐸P.S.: they shared this photo with their PI voluntarily 👍👏🥹

Give yourself the highest Valentine of all and apply to the Xenopus CSHL course! Applications due Feb 14! ❤️🐸❤️

Dr. Peter Walentek (Walentek Lab)@walenteklab.bsky.social · 2y ago

Remember, we have extended the deadline for applications until Feb 14th. Apply here: meetings.cshl.edu/courses.aspx...

Birth defects are diseases of development and are the #1 cause of death in the first year of life. And birth defects kill more than twice as many children as cancer. 4% of ALL hospitalizations (for all ages) are due to birth defects. Economic impact of birth defects is > 22 billion dollars per year.

A happy lab update. We have healthy froglets! 🐸💚 We switched everything to RO, and that fixed it. Not sure exactly what's going on, but we think that somewhere, someone is accidentally backwashing acid into the demineralized water system. More investigation is required. 🐸 🧪