Asthma: A team from @fzborstel.bsky.social and @unibonn.bsky.social has discovered a previously unknown mechanism of action of a synthetic peptide that dampens the excessive inflammatory responses associated with #allergic #asthma: advanced.onlinelibrary.wiley.com/doi/10.1002/...
Membrane‐Active Peptide Protects Against Inflammation by Targeting NLRP3 Activation at the Trans‐Golgi Network
The membrane-active peptide Pep19-2.5 reduces harmful inflammation by blocking activation of the NLRP3 inflammasome at trans-Golgi network membranes. By targeting key membrane interactions, Pep19-2.5...
advanced.onlinelibrary.wiley.com