Erez, Omri, Pasha, Roshina, and Ofir Cohen find HSCs lack transplant potency during Salmonella infection. HSCs recover! Molecular data point to proliferation. We have a great opportunity to realize the exhaustion/regeneration of our own adult stem cells now. www.sciencedirect.com/science/arti...
Roi Gazit
@gazitroi.bsky.social
Hematopoietic Stem Cells and Immunology. Doing science with peoples
Kudos to Dr. Idan Cohen! Finding of keratinocyte transcription factor in the essential role in immunocyte development. Keratinocyte differentiation transcription factor ZNF750 coordinates the development of epidermal immunocytes: Cell Reports www.cell.com/cell-reports...
Keratinocyte differentiation transcription factor ZNF750 coordinates the development of epidermal immunocytes
The coordinated development of immunocytes within the skin is a mystery. Adar et al. show that the epidermal transcription factor ZNF750, an essential driver of keratinocyte differentiation, also regu...
cell.com
באיחור של 6 שנים, ולמרות שהייתי מודע היטב לזכייה בנובל על המצאת בטריית הליתיום, גיליתי עכשיו שלאחד הזוכים קראו Goodenough. שזה חד משמעית, ובלי שום תחרות שם המשפחה הכי טוב ביקום, והעובדה שיש זוכה פרס נובל עם השם הזה, זה כל מדהים, שאני באמת לא מבין איך רק עכשיו התוודעתי לזה.
Normal adult stem cells are activatwd by immune stimuli, so here we learn that dirmant cancer cells are activated too. Better understand both normal and malignant stem cells is needed.
Hidden in the lungs of some breast cancer survivors are tumor cells that can remain dormant for decades — until they one day trigger a relapse. Now, experiments show for the first time these rogue cells can be roused from their slumber by common respiratory illnesses such as COVID-19 or the flu.
🚨 AAI is proud to announce the launch of the AAI RESTORE Grants Program, an $8M emergency funding initiative to support scientists whose immunology-focused federal research grants were abruptly terminated or frozen in 2025. 🔗 ow.ly/rwMU50Wy3Mp #AAIRESTORE
Amazing to see the broadening reach of HSC transplant-based therapies!!! 🩸 -> 🧠 www.science.org/doi/10.1126/...
Microglia replacement halts the progression of microgliopathy in mice and humans
Colony-stimulating factor 1 receptor (CSF1R) is primarily expressed in microglia. Its monoallelic mutation causes CSF1R-associated microgliopathy (CAMP), a major form of adult-onset leukoencephalopath...
science.org
#ISEH2025 🏯 in Kumamoto isn’t just about great science, it’s a chance to recharge. Unwind with a soak in a traditional hot spring, visit Kurokawa Onsen in the mountains or enjoy a luxury spa near Suizenji. 🛁 kumamoto.guide/en/spots/detail/1756
Kurokawa Onsen | Sightseeing | The Official Kumamoto Prefecture Website: More, More, Kuma-Motto!
Kurokawa Onsen, at an elevation of 700meters, is renowned as one of the most popular hot spring spots in Japan. Each Onsen Ryokan(inns) has different attractive open-air bath, Rotenburo.You can…
kumamoto.guide
Register now for the 7th German-French DNA Repair Meeting, which will take place at the Campus Pierre et Marie Curie of Sorbonne University in Paris, France, from 5–7 November 2025. premc.org/dnarepair202...
Just realized the #IUIS2025 go on twitter (what the XXX is that?), not yet promoted to BS So let's welcome immunologists to the present and future of science. And if you are around Vienna this August 17-23rd, drop by! iuis2025.org
Home - IUIS 2025
CHECK OUR CONFIRMEDKEYNOTE SPEAKERSMORE INFORMATION HERECHECK OUR CONFIRMEDPLENARY SPEAKERSMORE INFORMATION HERECME CREDITS AT IUIS 2025 IUIS is seeking Continuing Medical Education (CME) accreditatio...
iuis2025.org
Didn’t get your abstract submitted in time? Late breaking submission has just opened
It's not too late! The late-breaking call for abstracts for #ISEH2025 🏯 is now open. Submit your abstracts by 16 July for a chance to share your findings with world-leading scientists. www.iseh.org/2025abstracts
“I’m Rapping my PhD” Which conference does that?!?! Vaibhav Mahajan. Out of this world #theconferencetoendallconferences #TCTeAC
Sounds insane. GOV that was ekected to make america great is taking dangerous steps, this might significantlly weaken the USA
“His goal is to eliminate incentives to develop vaccines.” www.wsj.com/opinion/rfk-...
🚂 Off to Prague for @woodstocknightsci.bsky.social with @helenajambor.bsky.social @apoetsch.bsky.social and @jesseveenvliet.bsky.social 🔥🎉 #theconferencetoendallconferences!
@woodstocknightsci.bsky.social full awakening is only 3 nights from now! Follow #TCTeAC also known as #theconferencetoendallconferences!
#theconferencetoendallconferences ... choosing the walk up song was much harder than I thought ... in the thread below are the songs, which were considered but did not make it :-)
Even ChatGPT o.3 hallucinates papers when asked to do this. Submitting a narrative CV that includes papers that you didn't write and don't exist strikes me as a serious, actionable instance of academic misconduct. TERRIBLE ADVICE from Andrew's office of research services.
My institution's office of research services just completed a workshop on the use of narrative cv's (i.e., biosketches) in grant proposals. They are recommending the use of AI to read your CV and name your 5 greatest accomplishments. @carlbergstrom.com I would greatly appreciate your thoughts!
Scientists deciding to go to the "Woodstock of Biology 2 + Nightscience" #theconferencetoendallconferences
Don´t miss the Lab Spotlight of Tremblay Lab on #SimplyBlood. Read about their latest projects and accomplishments on simplyblood.org.
Lab Spotlight: Tremblay Lab
Tremblay Lab Each month, Simply Blood spotlights a lab contributing to the fields of hematology, immunology, stem cell research, cell and ge...
simplyblood.org
Terribly irritating: those who do not realize the advantage of diversity, and the need to encourage further inclusion, do not know evolution (well, some of them deny Darwin, and call for "eugenics", which is funny)
Can't believe it is 2025 and we are posting things like this: www.nature.com/articles/d41...
Perfectly UNFAIR to publish w/o letting the project leaders respond. Text provides little information. Old techniques are being used, massively. We must test multiple approaches. Fairness = let NIH managers say why they support the trial.
People who design & study vaccines are wondering why the #NIH is sinking half a billion dollars into trying to develop a platform for universal flu & covid vaccines using a decades-old production approach. “There is incredible work going on. This is not it." www.statnews.com/2025/05/03/n...
This is one of the best ads I have ever seen and I can’t believe I missed it
Peer review is not "gold". Hey- you do it for free!! But until we get a better method, that how things work. For the best and worse of it.
I reviewed a paper recently. It was flawed & rejected. It later appeared unchanged in another journal. So how is peer review a “gold standard”? You can’t have a gold standard if people can’t tell the difference between gold and bauxite..
Super interesting- aging and altered intestinal barrier function results in circulation of bacterial metabolites that drive clonal hematopoiesis. #Hematopoiesis #Blood #Aging www.nature.com/articles/s41...
Microbial metabolite drives ageing-related clonal haematopoiesis via ALPK1 - Nature
ADP-heptose binds to ALPK1, triggering transcriptional reprogramming and NF-κB activation, endowing pre-leukaemic cells with a competitive advantage due to excessive clonal proliferation.
nature.com
That spring time
Asthma and chronic rhinosinusitis share immune mechanisms, showing distinct endotypes that enhance treatment strategies and patient outcomes. by Kato A and Kita H in Nat Rev Immunol #MedSky 👉 get more here 📖 read the article:
Don't miss your chance to submit an abstract to #ISEH2025 🏯! With 20+ short talk slots available, selected presenters may be invited to share their work on stage. Deadline to submit is 12 May. www.iseh.org/2025Abstracts