New paper alert 🔬 We helped fund George Robinson's (UCL) study in Annals of the Rheumatic Diseases. It finds LAMP3 as a biomarker for interferon activity in childhood #lupus, guiding personalised treatment. 📄 Paper: ard.eular.org/article/S000... 🧪 Lupus explained: youtu.be/bXHFWIwRWE0

Type I interferon endotypes drive divergent clinical trajectories in childhood-onset SLE uncovered through a novel systems immunology approach

Childhood-onset systemic lupus erythematosus (cSLE) is a severe autoimmune disease with significant morbidity and enhanced type I interferon (IFN-I) signalling, potentially contributing to its aggress...

ard.eular.org

🦋 𝐓𝐨𝐝𝐚𝐲 𝐢𝐬 #𝐖𝐨𝐫𝐥𝐝𝐋𝐮𝐩𝐮𝐬𝐃𝐚𝐲❗ And now it is easier than ever to raise #LupusAwareness thanks to #Lupus100 and #LupusGPT! Check https://lupus100.org/ & https://lupusgpt.org & find reliable information about #lupus in many languages! #MakeItCount #MakeLupusVisible

Happy #DayOfImmunology! With help from @britsocimm.bsky.social, we turned ImmuNinjas into a short animation to make the immune system fun and engaging to understand. Free for teaching use👇 youtu.be/8F9Ovw-zFUs?... @efis-immunology.bsky.social @iuis-online.bsky.social @iuisjuniorcomm.bsky.social

⏰ 👀 #DayofImmunology @britsocimm.bsky.social @efis-immunology.bsky.social @iuis-online.bsky.social

📚@georgerobinson.bsky.social from @britsocimm.bsky.social explores #RegulatoryTCell in autoimmune diseases —highlighting their key role in immune balance and future therapies💡 🏆He also reflects on their recognition by the 2025 Nobel Prize 🌍🧡 Happy #DayofImmunology! #ThankyouImmunology

Great to reflect and celebrate tonight @ucl.ac.uk, including the amazing @domearlycareers.bsky.social team and fantastic @uclmedsci.bsky.social colleagues. Congratulations all! @bcellsrosser.bsky.social @pilaracedo.bsky.social

We have a new YouTube Channel! Please follow and subscribe here: www.youtube.com/channel/UChp... We'll be highlighting our amazing researchers across career stages with short interviews each month… taking over from our BlueSky Highlights….

Ageing Rheumatology and Regenerative Medicine

Based within the UCL Division of Medicine, The Department of Ageing, Rheumatology & Regenerative Medicine combines different disciplines to improve health and find new cures for disease. Our departmen...

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Go team! @heather--cross.bsky.social and @ciurtinlab.bsky.social presenting at the @mrc-lms.bsky.social Sex Differences in Biology Symposium! @arrdept-ucldom.bsky.social

Our second annual meeting - please save the date and distribute

🚨New paper from the lab! Type I interferon endotypes drive divergent clinical trajectories in childhood-onset SLE uncovered through a novel systems immunology approach 📖Read here in Annals of the Rheumatic Diseases: doi.org/10.1016/j.ar... 🙏Huge thank you to all co-authors, funders, and patients!

✨January Issue✨| Insights into the pathogenesis of childhood-onset SLE in the past decade The authors highlight the severity of childhood‑onset SLE and the need for more research to improve outcomes. @georgearobinson.bsky.social bit.ly/4qgkrZ2 #Rheumsky #Medsky

Insights into the pathogenesis of childhood-onset SLE in the past decade - Nature Reviews Rheumatology

Childhood-onset SLE is characterized by high disease activity, severe organ damage and substantial treatment challenges. The authors of this Review provide an update on the advances in the understandi...

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✨January Issue✨| Featuring articles on: - Monogenic disorders of the TNF signalling pathway (🔓: rdcu.be/eVOXL) - Pathogenesis of childhood-onset SLE - Mechanisms of osteoclast activation - WHO Benchmarks for Equitable Hip-Fracture Care in Older Persons (🔓) bit.ly/4sehpqc #Rheumsky #Medsky

Early Christmas present. Absolutely loving this from @immunologypodcast.com!

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UCL Dept of Aging, Rheumatology & Regenerative Medicine@arrdept-ucldom.bsky.social · 9mo ago

Wow! What a week.. our #BSI25 Congress in stats: 3 invited talks 3 selected for abstracts for short talks 1 lunch industry talk and… 14 posters! Not bad for a department less than 1 yr old 👏🏼

Delighted to share our new @natrevrheum.nature.com article: “Insights into the pathogenesis of childhood-onset SLE in the past decade” Grateful to an amazing team of co-authors and editors for building and shaping this work. We hope it helps the field and guides future discoveries.

Nature Reviews Rheumatology@natrevrheum.nature.com · 10mo ago

There's a new episode out now! Dr. @georgearobinson.bsky.social from @ucl.ac.uk talks about his research on #lupus and #SexDifferences in autoimmunity. 📍 https://bit.ly/3JL4pXI

Review @natrevrheum.nature.com @georgearobinson.bsky.social @ucl.ac.uk Insights into the pathogenesis of childhood-onset SLE in the past decade www.nature.com/articles/s41...

Career highlight being asked to be on one my favourite podcasts! Had lots of fun recording this with Brenda Raud and Jason Goldsmith on the @immunologypodcast.com Great to chat research and spread the word about lupus. Please go check it out!

Immunology Podcast@immunologypodcast.com · 10mo ago

There's a new episode out now! Dr. @georgearobinson.bsky.social from @ucl.ac.uk talks about his research on #lupus and #SexDifferences in autoimmunity. 📍 https://bit.ly/3JL4pXI

#Throwback 🧪 REVIEW | Dysregulated cellular metabolism in atherosclerosis: mediators and therapeutic opportunities A Yurdagul et al.

Dysregulated cellular metabolism in atherosclerosis: mediators and therapeutic opportunities - Nature Metabolism

Yurdagul and colleagues offer an integrated picture of metabolic changes at the cellular and at the lesion level in atherosclerosis.

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It’s the last day of #LupusAwarenessMonth Please spread the word to help improve the lives of patients You can also grab a copy of our book explaining how lupus develops in the body in an interpretable and accessible way: The Zombie Invasion All profits go to lupus charities amzn.eu/d/5qdGIOe

As we near the end of #LupusAwarenessMonth, I hope this video with @royalfreecharity.org helps highlight why research is so important to help improve the lives of patients, particularly those with younger onset disease. Thank you for this support and please raise awareness! youtu.be/bXHFWIwRWE0?...

Personalising lupus treatment: Dr George Robinson’s research

YouTube video by Royal Free Charity

youtu.be

Royal Free Charity@royalfreecharity.org · 10mo ago

For Lupus Awareness Month, we’re spotlighting George Robinson’s work on personalised therapies for lupus - research funded by your support. He’s studying treatments that could reduce symptoms. Watch the full interview via the link in our bio. #LupusAwarenessMonth #Research #NHS

Congrats @heather--cross.bsky.social on a great talk at the EFIS sex difference meeting today! @arrdept-ucldom.bsky.social

Catch these fantastic session openers from @heather--cross.bsky.social and @bcellsrosser.bsky.social this morning, both presenting sex differences #immunosky research from @arrdept-ucldom.bsky.social!

Immune Sex Differences@sexdiffimmunity.bsky.social · 10mo ago

Today we meet face to face for the first time!

Simple things are always the best 🎃

Loved it! Thank you @lydiabeckeriii.bsky.social for hosting me and @madhvimenon.bsky.social for the invitation to speak in this fantastic @britsocimm.bsky.social MIG seminar series! Really impressed with the research going on and great to make new collaborations. See most of you at #BSI25 congress!

Lydia Becker Institute @lydiabeckeriii.bsky.social · 11mo ago

This afternoon, we're excited to be joined by @georgearobinson.bsky.social from @ucl.ac.uk for our next @britsocimm.bsky.social MIG seminar: “The interferon nexus: sex differences, autoimmunity, and cardiovascular disease” 📅 Thursday 16th October 🕐 3 pm 📍 Michael Smith Lecture Theatre #ImmunoSky

This afternoon, we're excited to be joined by @georgearobinson.bsky.social from @ucl.ac.uk for our next @britsocimm.bsky.social MIG seminar: “The interferon nexus: sex differences, autoimmunity, and cardiovascular disease” 📅 Thursday 16th October 🕐 3 pm 📍 Michael Smith Lecture Theatre #ImmunoSky

Heading up to Manchester this morning to speak in the @britsocimm.bsky.social Manchester Immunology Group Seminar Series @lydiabeckeriii.bsky.social Looking forward to it!

Surprisingly, it is not yet obvious to all researchers and funding agencies that sex and gender matter in research, and should be recorded and addressed properly. So we wrote it authors.elsevier.com/c/1lxSmbah1w...

Fantastic to see and congratulations! Did you know there are sex differences in Tregs too? Check out our paper published in @thelancetrheum.bsky.social doi.org/10.1016/s266... @jury-lab.bsky.social @ciurtinlab.bsky.social @inespinedatorra.bsky.social

Science News@scinews.bsky.social · 11mo ago

The 2025 #NobelPrize in Physiology or Medicine has been awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi “for their discoveries concerning peripheral immune tolerance.”