Ghanendra Singh
@ghanendra.bsky.social
Research Interests in astrocytes, working memory, neuromorphic computing. Looking for PhD positions. https://sghanendra.github.io/
Pleasure attending #Memrisys 2026 and meeting Prof. Leon Chua was delightful 🤩. Have listened to his insightful “The Chua Lectures” to try and understand the local activity principles behind complex emergent phenomena such as spiral 🌀 or scroll waves seen in biological systems 🧠.
Thought this would be a nice way to enter the bsky community👇Delighted for Katie (now in Chris Dulla's lab at Tufts). Thank you to our collaborators, to the reviewers and to Cagla Eroglu for the highlight! www.science.org/doi/10.1126/...
Norepinephrine signals through astrocytes to modulate synapses
Locus ceruleus (LC)–derived norepinephrine (NE) drives network and behavioral adaptations to environmental saliencies by reconfiguring circuit functional connectivity, but the underlying synapse-level...
science.org
We identified how mechanical forces shape myelin development. The TMEM63A channel in oligodendrocytes converts physical cues into molecular signals that control myelin growth. Oligodendrocyte mechanotransduction channel TMEM63A regulates myelin sheath geometry: Neuron www.cell.com/neuron/fullt...
Oligodendrocyte mechanotransduction channel TMEM63A regulates myelin sheath geometry
Dereddi, Djannatian, and colleagues show that oligodendrocytes use mechanical cues to measure axon size. The stretch-activated channel TMEM63A converts membrane tension into calcium signals, which cal...
cell.com
Motivated reasoning with confirmation bias: Sometimes “We don’t reason to discover the truth, we reason to justify what we already believe.”
Really nice work from the Holmes lab looking at amygdala astrocytes in fear memory and extinction! www.nature.com/articles/s41...
Astrocytes enable amygdala neural representations supporting memory - Nature
Astrocytes in the basolateral amygdala dynamically track fear state and support fear memory retrieval and extinction.
nature.com
🎉 Great news! Our paper is now published in @naturecomm We identify a specific astrocyte ensemble that mediates THC-induced cognitive impairments during adolescence Huge thanks to our collaborators @marsicanolab @khakhlab @grandeslab 🔗 rdcu.be/eY0Or @jsromero.bsky.social @crismonteagudo.bsky.social
Scientific knowledge flourishes as a non zero-sum nature, nurtured by intellectual freedom and shared inquiry. However, this beauty is frequently undermined by systems that operate on zero-sum logic.
Elegance of a model lies in the simplicity of predicting a phenomena emerged based on intuitive believe 🤔, and understanding of the nature of reality captured by abstract imagination 💭 that are observed experimentally 👀, realised or discovered at a later stage.
Human 🩸🧠⏹️ #BBB on a chip 🤩
MIMETAS@mimetas.bsky.social · 9mo ago🧠 A fluorescence image of a human BBB model combining HBMECs, astrocytes, and pericytes. Claudin-5 (green), GFAP (red), and Hoechst (blue) reveal organized BBB architecture supporting studies of BBB function and drug transport. Discover the model: shorturl.at/APOzu
Microglia and Astrocytes in ASD.
TRAstonDrs@castltrastondrs.medsky.network · 9mo ago#Medsky🧪 #pedsky #Neurosky #publichealth In #AutismSpectrumDisorder (ASD), non neuronal cells specifically microglia & astrocytes are now recognized as leading contributors to the excitatory/inhibitory (E/I) network imbalance @brainbehavimm.bsky.social www.sciencedirect.com/science/arti....
Wanna compare dynamics across neural data, RNNs, or dynamical systems? We got a fast and furious method🏎️ The 1st preprint of my PhD 🥳 fast dynamical similarity analysis (fastDSA): 📜: arxiv.org/abs/2511.22828 💻: github.com/CMC-lab/fast... I’ll be @cosynemeeting.bsky.social - happy to chat 😉
Distinct endocannabinoids specifically signal to astrocytes or neurons in the adult mouse hippocampus www.nature.com/articles/s41...
Distinct endocannabinoids specifically signal to astrocytes or neurons in the adult mouse hippocampus - Nature Neuroscience
Distinct endocannabinoids signal to either astrocytes or neurons, evoking contrasting regulation of synaptic function. This works reveals the high degree of complexity of neuronal and astrocytic signa...
nature.com
📢Join our first seminar in 2026! Anna Orr, PhD, Associate Professor of Neuroscience at Weill Cornell, will give a talk on “Astrocytes in Neurocognitive Function and Dementia Pathogenesis” on Thursday, January 15.
International Conference on Mathematical Neuroscience @ McGill University, Montreal, Canada 2 – 5 Jun 2026 www.crmath.ca/en/activitie...
Activities - Site officiel du Centre de recherches mathématiques (CRM)
crmath.ca
ATgliaNet Symposium 2026 March 20th, 2026 | Vienna Keynote speaker Prof. Leda Dimou (University of Ulm) Registration & abstract submission until Feb 13: https://loom.ly/33SkUKk Find more glia related meetings here: https://loom.ly/dwKZ1r8
ATgliaNet Symposium 2026, March 20th, 2026 | MedUni Wien
Following last year’s successful inaugural symposium at ISTA, we are proud to announce the ATgliaNet Symposium 2026, a one-day scientific meeting, with keynote speaker Prof. Leda Dimou (Medical Faculty, University of Ulm).
hirnforschung.meduniwien.ac.at
Astrocytes tuning plasticity during critical periods !!
The Transmitter @thetransmitter.bsky.social · 9mo agoAstrocytes put the brakes on brain plasticity in mice by secreting the protein CCN1 to stabilize existing circuitry, a Nature study shows. By Holly Barker #neuroskyence www.thetransmitter.org/astrocytes/a...
🌟 Only 6 months until #FENS2026! Soon, the #neuroscience community will come together to exchange ideas and explore the latest breakthroughs in neuroscience. 🧠 📍 Barcelona, Spain 🗓️ 6–10 July 2026 👉 Learn more and join us in #Barcelona: fensforum.org #FENS #FENSForum #NeuroscienceConference
Astrocytes control oxytocin-based maternal behavior via connexin 30 https://www.biorxiv.org/content/10.64898/2026.01.09.698569v1
New results! Computational models often rely on hand-crafted connectivity and imposed dynamics to produce traveling waves (TWs). We show how TWs can naturally emerge under biologically plausible conditions. Emergent Traveling Waves in Neural Circuits doi.org/10.64898/202... #neuroscience
Emergent Traveling Waves in Neural Circuits
Artificial neural networks achieve striking performance but do not capture a prominent neural property. Cortical activity is organized by structured spatiotemporal dynamics, traveling waves (TW), whic...
doi.org
Many cortical traveling waves spiral. Here's how and why. Cortical Field Model of Complex Spiral Traveling Waves doi.org/10.64898/202... #neuroscience
Cortical Field Model of Complex Spiral Traveling Waves
Complex spiral traveling waves observed experimentally occurs across the cortex. The underlying mechanisms responsible for generating such mesoscopic activity are not well understood. Understanding ho...
doi.org
Delighted to share our first preprint of the year! A project that we're all really proud of in the lab led by @ossamaghenissa.bsky.social with @mathiasgua.bsky.social in which we set out to test the role of basolateral amygdala astrocytes in anxiety behaviour. www.biorxiv.org/content/10.6...
Astrocytic Encoding of Threat in the Basolateral Amygdala
The basolateral amygdala (BLA) has long been implicated in threat detection and the generation of anxiety states. While previous experiments have demonstrated the important role of BLA principal neuro...
biorxiv.org
RMAAT: Astrocyte-Inspired Memory Compression and Replay for Efficient Long-Context Transformers https://arxiv.org/abs/2601.00426
Beautiful 🤩 !! Function as CIM.
allen institute@alleninstitute.org · 9mo agoIn this mesmerizing video by our #ElectronMicroscopy team, a layer 5 thin tufted neuron is revealed with blue dendrites and purple axon. As it progresses, we zoom into where it connects to a pyramidal cell. Explore our EM data at: microns-explorer.org
Modeling endfeet aging of BBB in PFC might give us interesting insights.
Blanca Díaz Castro@bdiazcastro.bsky.social · 12mo agoHappy to share the video Isabel Bravo-Ferrer and Katrine Gaasdal-Bech made to summarize the findings of our manuscript in Brain Communications (academic.oup.com/braincomms/a...) Age-dependent regional differences in features of the brain vasculature, including endfeet 💙! youtu.be/mwgh_H1mcLI?...
MERCs in astrocytic brain aging.
Dr Richard Monaghan@richardmonaghan.bsky.social · 2y agoNew review out today in Open Biology, a Royal Society publication on mitochondria-ER contacts and their potential use as therapeutic targets. doi.org/10.1098/rsob... @keavneylab.bsky.social @thebhf.bsky.social @official-uom.bsky.social @gensocuk.bsky.social
Mitochondrial transfer from satellite glial cells (SGC) to neurons protects against peripheral neuropathy; SGCs are capable of transferring mitochondria to dorsal root ganglia sensory neurons in vitro, ex vivo & in vivo (via tunnelling nanotubes) www.nature.com/articles/s41...
Happy new year everyone 🍾 To start the year we have a new webinar coming soon! Prof. Bo Peng from the Institute for Translational Brain Research in China will be our next speaker on January 13th. Check all the information in the flyer and add it to your calendar! 🧬🧠
