Our home department of Molecular Biology & Biochemistry at UC Irvine is looking to hire a new tenure-track assistant professor in the broad area of structural biology. Come be our colleague! recruit.ap.uci.edu/JPF09887 Please apply and/or share this post.

Assistant Professor in Structural Biology and Biochemistry, Department of Molecular Biology & Biochemistry

University of California, Irvine is hiring. Apply now!

recruit.ap.uci.edu

Herculean effort by the Wiles lab @UCIBioSci Congrats to the entire team and the first author postdoc Liz for this amazing cover art! Proud of #Nicholaslab members Naveena and Julio for the small role we played in this groundbreaking work

Nature Microbiology@natmicrobiol.nature.com · last yr.

"Phollow" the link to our May issue to read about... 💥lysing bacterial pathogens ⛽microbial alkane oxidation 🌱importance of seed-borne bacteria 🙅‍♀️protective antibodies for norovirus 🚰E. coli in urban drinking water ...and more!👇 www.nature.com/nmicrobiol/v...

We’re thrilled to be featured on the May cover of Nature Microbiology... And our Research Briefing is out now—check it out, it’s 🔥! www.nature.com/articles/s41...

‘Phollowing’ phage outbreaks in microbiomes with live fluorescence microscopy - Nature Microbiology

Phollow is an in vivo tagging approach for marking bacteriophages with fluorescent proteins while new virions are assembled in bacteria, enabling direct observation of phage outbreaks with single-viri...

nature.com

Nature Microbiology@natmicrobiol.nature.com · last yr.

"Phollow" the link to our May issue to read about... 💥lysing bacterial pathogens ⛽microbial alkane oxidation 🌱importance of seed-borne bacteria 🙅‍♀️protective antibodies for norovirus 🚰E. coli in urban drinking water ...and more!👇 www.nature.com/nmicrobiol/v...

"Phollow" the link to our May issue to read about... 💥lysing bacterial pathogens ⛽microbial alkane oxidation 🌱importance of seed-borne bacteria 🙅‍♀️protective antibodies for norovirus 🚰E. coli in urban drinking water ...and more!👇 www.nature.com/nmicrobiol/v...

Beautiful new work from our colleagues down the hall 🔬🥂

Liz Ortiz de Ora@ortizdeora.bsky.social · last yr.

I am thrilled to share the first manuscript from the Wiles lab! We present "Phollow", an in vivo phage-tagging approach that enables direct observation of phage outbreaks with single-virion resolution by live imaging. Here some highlights 👇 www.nature.com/articles/s41...

Our #CryoEM study on the binding of a Tarantula toxin to a full-length human voltage-gated sodium channel has been published. Very proud of the awesome people in my lab 🥳🥂 www.nature.com/articles/s41...

Structural basis of inhibition of human NaV1.8 by the tarantula venom peptide Protoxin-I - Nature Communications

Animal toxins can modulate action potentials and are important leads for therapeutics. Here, the authors use cryo-EM to show the interaction of the tarantula venom peptide Protoxin-I with a human volt...

nature.com

buckle up out there

Groundbreaking work by @matthewkhoward.bsky.social and Nicholas Hoppe (not on bsky?) from the @willowcoyote.bsky.social @amanglik.bsky.social labs. Mapping function to structure with deep mutational scanning to resolve the mechanisms of pH sensing GPCRs www.sciencedirect.com/science/arti...

Molecular basis of proton sensing by G protein-coupled receptors

Three proton-sensing G protein-coupled receptors (GPCRs)—GPR4, GPR65, and GPR68—respond to extracellular pH to regulate diverse physiology. How proton…

sciencedirect.com

Ok, trying to bring my community back together... I created a starter pack for lipids and membrane protein aficionados! Feel free to share, add and distribute, so we can come together again! 😍 go.bsky.app/AEeXh86

I see 2 dolphins and a croc image from not #cryoem

#cryoem grids don't have to be 3mm do they?

Here is a starter pack for CryoEM/ET enthousiasts To be completed go.bsky.app/JmQksC