Wait, what?! This isn’t about ribosomes? Check out our new work where we find that a #Legionella effector thought to target host translation instead targets metabolism by modifying a host glycolytic metabolite. Led by @drjoshblack.bsky.social www.cell.com/molecular-ce...

The Legionella pneumophila effector SidL is an adenylyltransferase that modifies the glycolytic intermediate 3-phosphoglycerate

Black et al. identify the L. pneumophila effector SidL as an adenylyltransferase that targets host glycolysis. SidL covalently modifies the glycolytic intermediate 3-phosphoglycerate (3PG) with AMP, g...

cell.com

Nature research paper: ZAK activation at the collided ribosome go.nature.com/4a9cika

ZAK activation at the collided ribosome - Nature

The kinase ZAK is activated at collided ribosomes to mediate the ribotoxic stress response.

go.nature.com

ribo💥ribo ⬅️ ZAK a sight to behold! revealed by the ribo dream team Vienna Huso @doubleshuang.bsky.social @greenlab.bsky.social @beckmannlab.bsky.social

Beckmann Lab@beckmannlab.bsky.social · 9mo ago

How does the kinase ZAK sense ribosome collisions? Find out in our latest collaboration with the @greenlab.bsky.social @doubleshuang.bsky.social @Vienna Huso: 1/4 rdcu.be/eRmJl #ribosome #cryoEM #LMU #JHMI

Big congrats to the entire team from the @beckmannlab.bsky.social and @greenlab.bsky.social, in particular first author Vienna!

How does the kinase ZAK sense ribosome collisions? Find out in our latest collaboration with the @greenlab.bsky.social @doubleshuang.bsky.social @Vienna Huso: 1/4 rdcu.be/eRmJl #ribosome #cryoEM #LMU #JHMI

Check out our latest work on how collided ribosomes activate the MAP3K ZAK! 💫 www.nature.com/articles/s41... A fun collaboration with @beckmannlab.bsky.social @doubleshuang.bsky.social

ZAK activation at the collided ribosome - Nature

The kinase ZAK is activated at collided ribosomes to mediate the ribotoxic stress response.

nature.com