Biology and therapeutic potential of extracellular vesicle targeting and uptake

Nature Reviews Molecular Cell Biology, Published online: 02 January 2026; doi:10.1038/s41580-025-00922-4Extracellular vesicles are released from almost all cell types and mediate intercellular communication by delivering proteins, nucleic acids and lipids. This Review examines extracellular vesicle uptake by recipient cells, their effects on signalling and their therapeutic potential and limitations.

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Biology and therapeutic potential of extracellular vesicle targeting and uptake - Nature Reviews Molecular Cell Biology

Extracellular vesicles are released from almost all cell types and mediate intercellular communication by delivering proteins, nucleic acids and lipids. This Review examines extracellular vesicle upta...

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Genetic tools for investigating the life cycle of extracellular vesicles

Nature Reviews Bioengineering, Published online: 17 March 2025; doi:10.1038/s44222-025-00286-6A thorough understanding of the life cycle of extracellular vesicles is essential to unleash their full potential in biomarker identification and therapeutics…

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