We are excited and proud to share that the super talented @maheandria.bsky.social will be starting her own lab as an assistant professor and group leader at @neuropsi.bsky.social this fall 🥳🍾
The Hassan Brain Development Team
@hassanbraindevlab.bsky.social
We study the genetic control and molecular regulation of brain development - and a little bit of function - in fly, mouse and human stem cell models
A conversation with @bassemh.bsky.social on Mark Mattson's Brain Ponderings podcast: youtu.be/fdb8LE91pEc?... Also at open.spotify.com/episode/2LcO...
Bassem Hassan: Normal Functions of the Amyloid Precursor Protein in the Developing and Adult Brain
YouTube video by BRAIN PONDERINGS podcast with Dr. Mark Mattson
youtu.be
Ania Chrzanowska and @bassemh.bsky.social discuss why it is informative to think about neuronal circuit function from a developmental perspective. www.sciencedirect.com/science/arti...
Building brains, shaping behaviors: How developmental approaches illuminate the analysis of circuits and behavior
Developmental processes define the parameters of neural circuits and restrict the range of possible behaviors. Here, we briefly highlight how the deve…
sciencedirect.com
Herzlichen Glückwunsch an den ehemaligen Einstein Visiting Fellow Bassem Hassan @hassanbraindevlab.bsky.social 🎉
Internationale #Spitzenforschung in Berlin: Prof. Dr. Bassem Hassan hassanbraindevlab.bsky.social vom #ParisBrainInstitute kommt mit dem Humboldt-Forschungspreis an die #FUBerlin und bringt neue Perspektiven auf die Entwicklung des Gehirns mit. 🧠 ℹ️ www.fu-berlin.de/presse/infor...
The 2026 Visual System Development GRC and GRS are fast approaching. Jeremy Kay, Kristen Kwan, Robert Johnston, and I have built an exciting program that we hope you will enjoy. Looking forward to seeing everyone at the meeting this summer in beautiful Maine. Register and RT!
I owe this “career award” to everyone who has been part of @hassanbraindevlab.bsky.social over the years ❤️
On post-translational modifications & their contribution to help shape human cortical development 🧠 Jawdat Sandakly covers a recent #preprint from Julien Pigeon and colleagues @hassanbraindevlab.bsky.social. #DevBio #Neuroscience Read the #preLight ⬇️👀 prelights.biologists.com/highlights/p...
Post-translational Tuning of Human Cortical Progenitor Neuronal Output - preLights
On post-translational modifications and their contribution to help shape human cortical development
prelights.biologists.com
Please check out and RT this new position for an exciting collaborative project with @boninlab.bsky.social and @franckp.bsky.social on the links between human-specific mechanisms and neurodevelopmental disorders in cortical circuits.
Please repost widely. @vanderhaeghenp2.bsky.social and I are hiring a postdoc with expertise in sensory physiology and in vivo circuit imaging/manipulation. The project centers on human-specific brain development and SYNGAP1-related disorders. Call closing soon—apply ASAP jobs.vib.be/j/119852/pos...
Today we had the pleasure of hosting Dr. Bassem Hassan @hassanbraindevlab.bsky.social from @institutducerveau.bsky.social at our #SeminarsIN with his talk: “Temporal control of neurogenesis” A fantastic lecture, thank you! 👏👏 @csic.es @dicv.csic.es @umh.es @borrell-lab.bsky.social
We have the pleasure of welcoming Dr Bassem Hassan @hassanbraindevlab.bsky.social from @institutducerveau.bsky.social tomorrow at #SeminarsIN 🙌 He is a world leader in the study of genetic regulation of brain development. Don’t miss it! @borrell-lab.bsky.social @csic.es @dicv.csic.es @umh.es
A wonderful collaboration with @alexbaffet.bsky.social @boyanbonev.bsky.social and @neurogenesis-i3s.bsky.social labs
www.biorxiv.org/content/10.1... Our latest: Julien Pigeon and colleagues discover a mechanism linking post-translational modification of transcription factors to remodeling the chromatin landscape to regulate human cortical neurogenesis
www.biorxiv.org/content/10.1... Our latest: Julien Pigeon and colleagues discover a mechanism linking post-translational modification of transcription factors to remodeling the chromatin landscape to regulate human cortical neurogenesis
Post-translational Tuning of Human Cortical Progenitor Neuronal Output
The striking expansion of the human neocortex is driven by the ability of radial glial cells (RGCs) to prolong neurogenesis without exhausting their progenitor pool, thereby producing more neurons, pa...
biorxiv.org
Latest from the lab: the immensely talented Johnny Bou Rouphael and Laila El Khattabi in the team report the discovery and functional analysis defective splicing in a human developmental disorder. www.linkedin.com/posts/bassem...
Heterozygous pathogenic variants in the splicing factor SF1 lead to a large spectrum of neurodevelopmental disorders | Bassem Hassan
Latest from the lab: the immensely talented Johnny Bou Rouphael and Laila El Khattabi in the team report the discovery and functional analysis defective splicing in a human developmental disorder.
linkedin.com
For those who understand Arabic 😊 A podcast about @bassemh.bsky.social work and career. Thank you Haifa Alhadyian, PhD for this amazing initiative. www.linkedin.com/posts/activi...
الحلقة الأولى من بودكاست "مقابلات مع علماء عرب حول العالم" متاحه للإستماع الآن 🎙️ 🧠 🔬 .. ضيفي للحلقة الأولى هو الدكتور باسم حسن (Bassem Hassan)، قائد فريق في معهد باريس للدماغ في فرنسا في ...
الحلقة الأولى من بودكاست "مقابلات مع علماء عرب حول العالم" متاحه للإستماع الآن 🎙️ 🧠 🔬 .. ضيفي للحلقة الأولى هو الدكتور باسم حسن (Bassem Hassan)، قائد فريق في معهد باريس للدماغ في فرنسا في تخصص علم ا...
linkedin.com
Excited to share our latest paper in Nature Communications! We uncovered a dev-time transcriptional program (via Mirana → Pink1) that shapes mitochondria & circuit wiring. Disrupt it early, and neurons miswire — even if the gene recovers later!
Latest from the lab, the beautiful work of Iryna Mohylyak and colleagues describing a temporal developmental transcriptional program for mitochondrial quality control and synaptic connectivity, with @jdejuan-sanz.bsky.social, Olga Corti and @steinaerts.bsky.social labs www.nature.com/articles/s41...
Registration is now open for 2026 GRC on Neural Development @neuraldevgrc.bsky.social Register early because places go fast!
Latest from the lab, the beautiful work of Iryna Mohylyak and colleagues describing a temporal developmental transcriptional program for mitochondrial quality control and synaptic connectivity, with @jdejuan-sanz.bsky.social, Olga Corti and @steinaerts.bsky.social labs www.nature.com/articles/s41...
Temporal transcriptional regulation of mitochondrial morphology primes activity-dependent circuit connectivity - Nature Communications
This study investigates the developmental transcriptional regulation of mitochondrial quality control. Authors identify the Drosophila factor Mirana, homologous to mammalian TZAP, as a key temporal re...
nature.com
👋🏻 Bluesky!
Bassem Hassan @bassemh.bsky.social, Corey Harwell & yours truly are co-chairs for 2026 Neural Development #GRC August 2-7, 2026 in Newport, RI 🇺🇸 - if you are interested in updates on the conference & to hear about our 🤩 line-up of speakers...follow @neuraldevgrc.bsky.social! 🧠🪰🐭🐙🐸🦎🧒🏻🧫🧪🧠
Bassem Hassan @bassemh.bsky.social, Corey Harwell & yours truly are co-chairs for 2026 Neural Development #GRC August 2-7, 2026 in Newport, RI 🇺🇸 - if you are interested in updates on the conference & to hear about our 🤩 line-up of speakers...follow @neuraldevgrc.bsky.social! 🧠🪰🐭🐙🐸🦎🧒🏻🧫🧪🧠
Congrats to the fantastic @maheandria.bsky.social on this well deserved recognition from French Academy of Science
It is a Great Honour to receive the 'Les Grandes Avancées en Biologie' award 🏅 from the @academiesciences.bsky.social and to share our work during this fabulous day celebrating Science. Thank you! @hassanbraindevlab.bsky.social @institutducerveau.bsky.social @frm-officiel.bsky.social
This journey began in Berlin with @bassemh.bsky.social and Robin Hiesinger, and continued at @institutducerveau.bsky.social in @hassanbraindevlab.bsky.social , with the generous support of @frm-officiel.bsky.social . Grateful to the von Kleist & Stoeckli Labs and all co-authors!
A temporal sequence of genetically encoded stochastic mechanisms explains variation in stereotyped neuronal circuits in Drosophila 🧪🧠 @bassemh.bsky.social @maheandria.bsky.social @hassanbraindevlab.bsky.social @institutducerveau.bsky.social www.nature.com/articles/s41...
Sequential and independent probabilistic events regulate differential axon targeting during development in Drosophila melanogaster - Nature Neuroscience
The developmental origin of behavioral individuality is unclear. The authors show that a temporal sequence of genetically encoded stochastic mechanisms explains variation in stereotyped neuronal circu...
nature.com
New from the lab: @maheandria.bsky.social and colleagues in collaboration with the Hiesinger, Stoeckli and von Kleist labs dissect the sequential emergence of axonal targeting during development in today's issue of Nature Neuroscience: rdcu.be/ek010
Sequential and independent probabilistic events regulate differential axon targeting during development in Drosophila melanogaster
Nature Neuroscience - The developmental origin of behavioral individuality is unclear. The authors show that a temporal sequence of genetically encoded stochastic mechanisms explains variation in...
rdcu.be
Hot off the press: The excellent Maheva Andriatsilavo and colleagues show how a temporal sequence of stochastic molecular mechanisms allow the emergence of stereotyped individualised neuronal circuits. Just published in Nature Neuroscience: rdcu.be/ek010
Sequential and independent probabilistic events regulate differential axon targeting during development in Drosophila melanogaster
Nature Neuroscience - The developmental origin of behavioral individuality is unclear. The authors show that a temporal sequence of genetically encoded stochastic mechanisms explains variation in...
rdcu.be
Anna CHRZANOWSKA, PhD, postdoc in The Hassan Brain Development Team @hassanbraindevlab.bsky.social is organizing a trainee-led symposium @institutducerveau.bsky.social June 2-4 Spread the word! nenckiopenlab.org/decoding/
Nencki Open Lab
Decoding the brain: from methods to meaning Paris Brain Institute, June 2-4th 2025 Applying machine learning and other models to decode behavioral parameters from neural activity is now a standard …
nenckiopenlab.org
Can't miss opportunity for anyone interested in developmental timing!! See you in Paris⏳️
Join us in Paris 6-9 May 2025 for the #EvoDevoTempo conference (2nd edition) with a fantastic line up of speakers confirmed!! Organized by @mdiazcuadros.bsky.social @vanderhaeghenp2.bsky.social @bassemh.bsky.social and me. Please RT to spread the word meetings.embo.org/event/25-dev...
Join us in Paris 6-9 May 2025 for the #EvoDevoTempo conference (2nd edition) with a fantastic line up of speakers confirmed!! Organized by @mdiazcuadros.bsky.social @vanderhaeghenp2.bsky.social @bassemh.bsky.social and me. Please RT to spread the word meetings.embo.org/event/25-dev...
Developmental timing across species: From mechanisms to evolutionary insights
Like choreography, development consists of a highly ordered suite of steps and transitions. Modifying developmental tempo can affect final size and composition of tissues, as well as their plasticity…
meetings.embo.org