did someone say sadder

Deeny they/them@geraldinepiche.bsky.social · yesterday

I bet the inventor of the microwave was like "no. Sadder."

I'm excited to be co-organizing the 2026 Midwest Microbial Pathogenesis Conference, which will take place Sept 25-27 on the UMN campus in Minneapolis! Poster abstracts due Aug 7! Submit yours & register here ➡️ mmpc2026.umn.edu

Bacteriology-Focused Assistant Professor Position in Microbiology and Immunology at the University of Michigan Application deadline: August 15, 2026 Come be my colleague!

I don’t think AI is the future and I’m 100% basing this on how nobody likes those kitchen trash cans with the powered lids.

Phenazine Pride #PrideMonth #bacterial_pigments Agar art by Marina Smiley

Preprint alert! Using smFRET, we define the only essential ATP hydrolysis step in translation initiation. We show that eIF3 and eIF4B stimulate ATP-hydrolysis-dependent recycling of cap-stalled eIF4F, coupling eIF4F recycling to PIC loading onto an mRNA.🔬 doi.org/10.64898/202...

You would like to exist today? That will be $200.

The M&I department/community at Dartmouth is fantastic. Apply!

George O'Toole (he/him/his)@geiselbiofilm.bsky.social · last mo.

Our Dept of Microbiology & Immunology @Geisel School of Medicine @Dartmouth has an opening for an Assistant Professor. Looking for programs bridging multiple areas in Micro & Immuno. A great place to be! Programs: www.M2P2.org www.dartmouthbiofilm.org Job ad: apply.interfolio.com/187637

Introducing an artisanal process for enhancing milk. Recently rediscovered for the health-conscious consumer, this process dates back to the 1800s. Totally organic and chemical free, we simply heat the milk gently for about 15 minutes.

Max Ritter@maxritter.bsky.social · 2mo ago

I love this photo of Louis Pasteur in his laboratory. Pasteurization is such a cool process and it's been amazing getting to design pasteurization systems for a living. #STEM

Additional fact: women were admitted to the last Ivy Leauge holdout in 1983, twenty years after being admitted to Space.

Prof Frank McDonough@fxmc1957.bsky.social · 2mo ago

FACT OF THE DAY. 16 June 1963. Soviet cosmomaut Valentina Tereshkova (aged 26) became 1st woman space traveller. In all her space missions, she orbited the Earth 48 times, spent almost 3 days in space and remains the only woman to have been on a solo space mission.

Structure determination and dual targeting of a plant TACO1 identifies its ancient role as an organelle translation regulator www.biorxiv.org/content/10.6...

Structure determination and dual targeting of a plant TACO1 identifies its ancient role as an organelle translation regulator

Ribosome stalling caused by polyproline (PPs) motifs is common. Their translation is enhanced by accessory proteins such as YebC in bacteria, whose homolog, TRANSLATIONAL ACTIVATOR OF CYTOCHROME C OXI...

biorxiv.org

Reminder — UW #Microbiology has an open search for an Assistant Professor, focusing on fundamental problems in #bacteriology! If you or someone you know would be suitable, here's the ad: apply.interfolio.com/185622

New insights into copper physiology in Bacillus subtilis. The outlines of the pathway for copper import and trafficking to support aerobic growth are emerging. Work led by Grayson Barnes, with support from our collaborators. doi.org/10.1128/mbio... #microsky #metalsinbiology

Pathways of copper import and utilization that support respiration in Bacillus subtilis | mBio

Copper is a critical micronutrient for bacteria; however, it is toxic in excess. This leads to the cell having tightly regulated import and export systems to prevent intoxication while having sufficient copper for cellular needs. Copper export has been well studied, but copper import and the effects of copper starvation are less defined. In this article, we characterize the Bacillus subtilis high-affinity copper importer YcnJ. We show that under copper limitation, the cell is deficient in copper-containing oxidases, which leads to respiratory defects. Copper imported by YcnJ is proposed to function in a pathway with other proteins implicated in the assembly of respiratory oxidases. More generally, this work contributes to the underexplored area of copper import and trafficking in bacteria.

doi.org

See our new latest pre-print for a study led by grad student Ian Reynolds, with current and former undergrads Isabel Westin and Caleb Wood in the lab. A study that goes to show how so many cell surface processes are connected to each other in bacteria. www.biorxiv.org/content/10.6...

Here is a link to my student Mitch's final published paper on the activity of Rad51 and Rad54 during the homology search. genesdev.cshlp.org/content/40/1...

Bacterial transmembrane proteins usually localize inside the cell by "finding" a pre-localized protein, but how did the 1st protein get there? @vanipande.bsky.social found a protein in #B.subtilis that localizes by recognizing a *lipid* localization cue. #Microsky www.biorxiv.org/content/10.6...

Diverse mechanisms of translation arrest by a Clostridia ribosome stalling peptide CliM - pubmed.ncbi.nlm.nih.gov/42151144/

Diverse mechanisms of translation arrest by a Clostridia ribosome stalling peptide CliM - PubMed

Ribosome arrest peptides undergo programmed translational stalling in response to changes in the cellular environment to feedback-regulate gene expression. CliM, an arrest peptide in Clostridia, is en...

pubmed.ncbi.nlm.nih.gov

These two new PhDs 💕 Congrats Dr. Callan and soon to be Dr. Prince!

Thrilled to share the updated video of my paper in Nature with Maciej (under supervision of @simonemattei.bsky.social & @jomaalab.bsky.social) Proud to use Cryo-ET to uncover how hibernation factors are key to translation restart! To model PTMs in situ and render animations fulfilled my PhD dream!🥹🎉

EMBL@embl.org · 3mo ago

Despite its name, SNOR, a newly discovered protein, is hardly asleep on the job. EMBL researchers’ newest technologies allowed their scientific collaboration to discover a tiny protein with a big role in awakening cells from dormancy to restart protein synthesis. www.embl.org/news/science...

The phenotypic landscape of the model firmicute Bacillus subtilis https://www.biorxiv.org/content/10.64898/2026.05.13.724699v1

We have a PhD position in Leiden within our #ERCSyG @microclockerc.bsky.social project to dissect circadian clocks in bacterial biofilms We are looking for candidates with optogenetics, single cell microscopy and image analysis background Application deadline 12 June 2026 👉 edu.nl/cqra3

Awesome work! Still so much to learn about ribosome hibernation!

Ahmad Jomaa@jomaalab.bsky.social · 3mo ago

Excited to share our work uncovering SNOR, a ribosome-associated factor that promotes translation restart after dormancy published in Nature!! This was, as usual, a wonderful collaborative effort between our group and the Mattei Lab @simonemattei.bsky.social @embl.org www.nature.com/articles/s41...

POSTDOC OPPORTUNITY!!! The Rutgers IRACDA program is phenomenal: 70% of postdoctoral fellows land faculty positions. Martha Soto (LinkedIn below) is the amazing director and leader of this program. Please apply or reach out if you have questions. www.linkedin.com/posts/martha...

INSPIRE is recruiting! Please share broadly with senior graduate students and beginning postdocs. INSPIRE, the NIH-funded Rutgers-IRACDA, offers postdoctoral training for individuals interested in… | ...

INSPIRE is recruiting! Please share broadly with senior graduate students and beginning postdocs. INSPIRE, the NIH-funded Rutgers-IRACDA, offers postdoctoral training for individuals interested in com...

linkedin.com

We are hiring @umichmicroimmuno.bsky.social ! Tenure-track assistant professor position in our Microbiology and Immunology department. We are especially looking for someone working in bacterial pathogenesis

The Biology Department at Syracuse University is hiring! Please share with anyone you think might be interested. www.sujobopps.com/postings/112...

Assistant Teaching Professor - Biology and Biochemistry

The Department of Biology at Syracuse University invites applications for a non-tenure-track Assistant Teaching Professor to teach Biology and Biochemistry undergraduate level classes, starting in fal...

sujobopps.com

Unexpected ribosome turnover during prolonged translation inhibition https://www.biorxiv.org/content/10.64898/2026.05.06.723260v1

🚨Faculty job search: University of Illinois Chicago Micro & Immuno department is hiring! Open rank and open area within host-pathogen interactions. Apply by May 31 to join us in UI College of Medicine in the heart of Chicago! uic.csod.com/ux/ats/caree...

Our paper is out today as an ASAP web publication in Biochemistry! Congrats to Swati Manjari and @calebmallery.bsky.social! pubs.acs.org/doi/10.1021/...

How Medically Important Antimicrobials Bind to the 30S Ribosomal Subunit in a Bacterial Pathogen

Ribosomes translate the genetic code in mRNA to synthesize proteins in all living organisms. Decoding of mRNA occurs in the small subunit of the ribosome and is mediated by tRNA anticodons. Regions ne...

pubs.acs.org

Here is the work of Jingyi Hu and David Moraga graduate students in my lab, published online in Plos Genetics journals.plos.org/plosgenetics...

Potential Rad54 separation of function mutation highlights unique roles during homologous recombination

Author summary Homologous recombination (HR) is a DNA double-strand break repair pathway that functions at DNA breaks and stalled or collapsed replication forks. Rad51 is a critical enzyme that mediat...

journals.plos.org

This one deserves it🤩! We used cryo‑EM to identify a new “sporesilk” in Bacillus thuringiensis. The fiber, called A‑ENA, forms an incredibly stable covalent network that increases virulence by keeping the toxic payload and spores in a biofilm-like structure. www.nature.com/articles/s41...

Auto-crosslinking sporesilk fibers promote endospore and Cry toxin clustering - Nature Communications

Authors reveal that protein nanofibrils govern assembly of bacterial spores and extrasporal toxins into insecticidal aggregates. Spores and parasporal bodies are incased in a “sporesilk” matrix that d...

nature.com