❗️Our next workshop will be on July 23rd, 6 pm CET on Introduction to Bayesian Multiple Imputation with the rblimp package Register or sponsor a student by donating to support Ukraine! Details: bit.ly/3wBeY4S Please share! #AcademicSky #EconSky #RStats

New post, on why we should stop telling people the normal distribution is in places that it isn't: kucharski.substack.com/p/no-the-nor...

No, the normal distribution isn't in your gym

And we should stop telling people it is

kucharski.substack.com

Two really useful reports on the Bundibugyo #Ebola outbreak from the @cmmid-lshtm.bsky.social team at LSHTM: - The multitude of benefits that safe and dignified burial can bring - The risk of exported cases cmmid.github.io/topics/ebola... #IDSky

Estimating the current size of the 2026 DRC Bundibugyo virus outbreak: a joint Bayesian re-analysis of the McCabe et al. report w/ @kathsherratt.bsky.social Sam Brand and @sbfnk.bsky.social

I'm pretty convinced by the recent Bayesian meta-analysis of selective decontamination of the digestive tract for ventilated patients. evidence.nejm.org/doi/10.1056/... I have to admit that I instinctively *really* don't like this as an idea (but hey - I guess that's what RCT evidence is for) #IDSky

Selective Decontamination of the Digestive Tract in Adult Mechanically Ventilated Patients — An Updated Systematic Review with Bayesian Meta-Analysis

There is uncertainty whether the use of selective decontamination of the digestive tract (SDD) as a preventive antimicrobial strategy reduces mortality in adult patients receiving mechanical ventil...

evidence.nejm.org

So far SNAP RCTs have confirmed my practices: 1) ✅ cefazolin 2) ❌ clindamycin #IDSky

Antibiotic Steward 🅱️C🆔🅿️🌟@absteward.bsky.social · 5mo ago

🔥 Late Breakers SNAP platform RCT| Adjunctive Clindamycin in S.aureus bacteraemia ❌ No mortality benefit 90d mortality:16.9% vs 15.2% aOR 1.16 (CrI cross 1) 📊PPSup(~7%)→Futility threshold reached ⚠️ICU subgp:numerically worse with clinda ⚖️CDAD:no # (~2%)😯 #ESCMIDGlobal2026 #idsky

Great speakers at this symposium - 22 April 2026 at LSHTM. Join online or in person (email if in person) to hear great talks at the cutting edge of Inequalities in infectious disease dynamics. www.lshtm.ac.uk/newsevents/e...

Inequalities in infectious disease dynamics symposium | LSHTM

Join us for the Social Inequalities in Infectious Disease Dynamics Symposium at the London School of Hygiene & Tropical Medicine (LSHTM). The day features a full programme of presentations and invited

lshtm.ac.uk

Lenacapavir is a great HIV prevention drug and I really hope Gilead agree to MSF's request to sell it to them so they can provide it to those who patently need it most. Some thoughts here: jackwgoodall.github.io/infection_up... #IDsky #globalhealth

This is indescribably sad development in an already appalling man-made humanitarian crisis

Athena Akrami@athenaakrami.bsky.social · 6mo ago

Pasteur Institute of Iran, founded in 1920 now destroyed by Israel-US bombing😞 It played a pivotal role in developing vaccines & public health services, for over a century, now gone😞 A few days ago a pharmaceutical plant was bombed, accused of making anesthetic fentanyl #War #PasteurInstituteIran

PLEASE SHARE. PhD Opportunity with me, Ben Raymond and Jan Engelstaedter and Andrew Letten at University of Queensland. Experimentally testing mechanisms of how temperature may change selection and spread of AMR in E. coli. Coupled with some advanced modelling and sequencing. 🧪🦠 #microsky

1/ Announcing the IDD Connect Series! #IDsky #EpiSky 🧪 ❓Interested in hearing from infectious disease dynamics organizations from different regions? 📣 IDD Connect is a monthly initiative to bring together the infectious disease dynamics global community 📧 Join GSIDD mailing list for event links👇

Join Us | GSIDD

gsidd.org

I've made a website for clinically relevant infection research: jackwgoodall.github.io/infection_up... It's in its early days but it has summaries of recent infection papers that caught my eye, an OpenAlex feed of recent infection papers from high impact journal and a resources section #IDSky

So this interview lasted 2 hours so this “you’re scaring me” part might seem like an overreaction or fearmongering to someone without that context. There’s a lot of evidence to support my hypothesis that a potential H5N1 pandemic would be worse than COVID.

Angie Rasmussen@angierasmussen.bsky.social · last yr.

Went on @60minutes.bsky.social to talk to Bill Whitaker about H5N1. As Kamran Khan from Bluedot told Bill, we don’t know if or when this virus might acquire pandemic capabilities, but it can. And if it does, as I told Bill, that will be worse than COVID. Much worse. www.cbsnews.com/news/bird-fl...

ID gurus - what are your thoughts on the optimal tx for S. pneumo meningitis that is pansensitive? ESCMID guidelines: PCN or amp/amox IDSA guidelines: PCN NICE guidelines: Ceftriaxone PCN: lower risk of CDiff, antimicrobial stewardship rizz Ceftriaxone: fewer infusions, pt already on this #IDsky

a woman says " i feel the conflict in you "

ALT: a woman says " i feel the conflict in you "

media.tenor.com

Our @shorten2trial.bsky.social aims to confirm that 7-day treatments are superior to 14-day courses for uncomplicated P. aeruginosa BSI. Check out our full protocol 👉🏻 journals.plos.org/plosone/arti... #AMSsky #IDSky

💉 How do we optimise the neutralising antibody responses of HSCT/CAR-T recipients following COVID vaccination? We found ChAdOx1-S recipients were EIGHT times more likely to have neutralising antibodies than those receiving mRNA vaccines in our new paper! Read more --> doi.org/10.1111/bjh....

Greater preservation of SARS‐CoV‐2 neutralising antibody responses following the ChAdOx1‐S (AZD1222) vaccine compared with mRNA vaccines in haematopoietic cell transplant recipients

Knowledge of factors impacting immune responses after COVID-19 vaccination is essential for guiding revaccination strategies in haematopoietic stem cell transplant (HSCT) and chimeric antigen recepto...

doi.org

BIA now on blue sky 👏 - and please consider applying for our ECR and small project grants!

British Infection Association@biainfection.bsky.social · 2y ago

Grants: we provide travel and research grants for infection trainees and undergraduates. Scientific committee chair: @thushan-desilva.bsky.social Our call for Early Career Research and Small Project Grants is open. Closing date 31st January 2025 www.britishinfection.org/research-gra...

This is a really useful insight that hopefully will guide how we prevent future spill overs

Jason Nickerson@jwnickerson.bsky.social · 2y ago

New preprint from Rwanda’s Marburg outbreak shows genetic evidence that the outbreak was due to a single spillover event, followed by human-to-human transmission that can be traced to the index case. 🧪🩺 IDSky www.medrxiv.org/content/10.1...

R markdown is an amazing way to share pre-publication findings with colleagues and collaborators. If you use R but haven't taken advantage of markdown then I have a tutorial just for you: jackwgoodall.github.io/floreytemplate It's new so I would love your feedback. #IDsky #AcademicSky #episky

New to this place 🦋, moving on from the other place Here to provide you #EpiSky #IDsky updates from Europe's weekly, peer-reviewed scientific journal on infectious disease epidemiology, prevention & control #PublicHealth Submit your papers now for our annual theme 2025 😷💉 bit.ly/annualtheme25

🧵Next week, you will see people using something called Benford's Law to try to prove election fraud. ⛔️These people are wrong⛔️ I am a scientist who has published on Benford's Law. Let me tell you what it is and why what they are doing is mathematically incorrect. 1/

This is an amazing idea - using microbiome assessments to account for the inaccuracies that are invariably present in self reported diet recall www.nature.com/articles/s41...

Microbiome-based correction for random errors in nutrient profiles derived from self-reported dietary assessments - Nature Communications

Here, the authors introduce METRIC, a deep-learning method that corrects measurement errors in self-reported dietary nutrient profiles using assessed data and microbial composition, effectively enhanc...

nature.com

Dear IDTwitter refugees I made an #IDSky starter pack which makes it easy to find accounts of ID clinicians, medical microbiologists, ID researchers, ID epidemiologists, ID focused reporters, and of course journals ahead of the curve. Let me know if I missed you! go.bsky.app/LnAQjdq

patrick star from spongebob squarepants is standing on a sandy beach next to a black line .

ALT: patrick star from spongebob squarepants is standing on a sandy beach next to a black line .

media.tenor.com

Did it. Got approval to stop posting at X. Please #IDSky #MedSky people, feel free to follow @cmicomms.bsky.social, ESCMID's #OpenAccess journal on all things #infectiousdiseases, #clinicalmicrobiology, #AMR, and host of the #Communicable podcast, so I can show that we were right! :-)

"Exposure to healthcare has a large role in the transmission of infectious diseases and acquisition and transmission of antimicrobial resistance" #IDSky #MicroSky #MedSky www.bmj.com/content/387/...

Protecting healthcare and patient pathways from infection and antimicrobial resistance

Innovative whole system approaches to integrate research and novel technologies within patient pathways are needed to target antibiotic use, minimise healthcare associated infections, and adapt to nov...

bmj.com

Towards shorter, safer, flexible, and more effective treatment regimens for drug-resistant tuberculosis #TB #IDSky 🩺🧪 #AMR www.thelancet.com/journals/lan...

Towards shorter, safer, flexible, and more effective treatment regimens for drug-resistant tuberculosis

There has been an important shift during the past 10 years in the approach to treating drug-resistant tuberculosis.1 Around a decade ago, the treatment of multidrug-resistant or rifampicin-resistant t...

thelancet.com

academic.oup.com/ofid/article... We have recently changed CSF viral panel and now get HHV6 results for all patients. Positive results in immunocompetent patients have caused a fair amount of debate (not least because of chromosomal integration). I found this review very helpful. #IDSky

Diagnostic Dilemmas: A Review of Reported Cases of Human Herpesvirus 6 Encephalitis in Immunocompetent Adults

Human Herpesvirus-6 Encephalitis is exceedingly rare amongst the immunocompetent population. This review article identifies the available records of HHV-6

academic.oup.com

The march of the mRNA vaccines goes on. Clostridiodes difficile (C diff) next... #IDSky #MicroSky #MedSky 🧪 www.science.org/doi/10.1126/...

A multivalent mRNA-LNP vaccine protects against Clostridioides difficile infection

Clostridioides difficile infection (CDI) is an urgent public health threat with limited preventative options. In this work, we developed a messenger RNA (mRNA)–lipid nanoparticle (LNP) vaccine targeti...

science.org

www.independent.co.uk/news/health/... We really need to get out of the mindset that outbreaks like this are only problematic when Western countries are at risk. This is devastating lives and healthcare systems in Rwanda.

Marburg virus outbreak: What you need to know as Europe fears cases

Virus, which has similarities to Ebola, has killed at least nine people during an outbreak in Rwanda

independent.co.uk