I just submitted an abstract for this amazing #ELIXIR 3D-BioInfo Annual General Meeting | #ISCB #3DSig taking place in beautiful #Rome later on this year in November! Talk abstract submissions deadline is tomorrow, 31 July. Find all the details here: www.iscb.org/3dbioinfo202...! See you in Rome!

Thrilled to introduce TEDLH, a library of profile HMMs built from TED’s structure-derived domain annotations of the AFDB. Explore 765K HMMs capturing CATH superfamily diversity. www.biorxiv.org/content/10.6...

bioRxiv Bioinfo@biorxiv-bioinfo.bsky.social · 7mo ago

TEDLH: Domain HMMs for sensitive detection of remote homologues https://www.biorxiv.org/content/10.64898/2026.01.07.697892v1

Hi, everyone. I did it! ✅ 💪 #Challenge complete: 31 days of 100 push-ups a day - finished! 🔥 I started this as a small personal commitment with a big purpose: to support @cancerresearchuk.org and help fund vital work in #cancer #research. 🎗️

Hi everyone! 👋 I wanted to share a small personal #challenge with a big #purpose: for the past 15 days I have been doing 100 push-ups a day, and I am committed to keep going for the next 16 days too. 💪 🔥 This is a @cruk-mi.bsky.social initiative to help fund vital work in #cancer #research. 🎗️

🎉 Happy #new #year to everyone! 📢 No better way to kickstart 2026 than by sharing our latest work, now available on #Open #Biology by @royalsociety.org. The title is "Mutations within the predicted fragment-binding region of FAM83G/SACK1G abolish ints interaction with the Ser/Thr kinase CK1α".

🌍 A couple of weeks ago, I had the pleasure of attending the annual #ISMB + #ECCB, international Conference on Intelligent Systems for Molecular Biology, organised by @iscb.bsky.social which took place in the magical city of #Liverpool!

🎓 📚 Last month, I was awarded my PhD degree by the University of Dundee. This marked the end of my 10-year journey as a student and closed an important chapter of my life in Dundee — a journey that began in 2017 as an #Erasmus exchange undergraduate student.

The @narjournal.bsky.social Annual Web Server Issue is now finalised. Congratulations to all other authors for their excellent resources. I am thrilled to share that one of our #LIGYSIS-web paper figures was selected as the cover image for this issue. Check it out here: lnkd.in/dXAb6jwv!

🎉 I am thrilled to share that our latest work on is now publicly available on @biorxivpreprint.bsky.social. The title is "Mutations within the predicted fragment-binding region of FAM83G/SACK1G abolish ints interaction with the Ser/Thr kinase CK1α". 🔗 Pre-print: www.biorxiv.org/content/10.1...

My #PhD #Thesis: "Computational methods for the characterisation and evaluation of protein-ligand binding sites" is now #publicly #accessible! I also shared the #GitHub #repository I used during the writing period. 📖 Thesis: tinyurl.com/utges-thesis 🔗 Repo: tinyurl.com/utges-thesis...

I'll be attending the @iscb.bsky.social #ISMBECCB2025 conference in Liverpool from July 20-24. Who else is coming? Register here and don't miss it. It's going to be great! invt.io/1bxbm6fohph I'll present my PhD work at the @bartongrp.bsky.social on protein-ligand interactions at the 3DSIG panel!

🌼 Jalview and The Daffodil DNA Project were at the 2025 Conference @associationscied.bsky.social this weekend with colleagues from James Hutton. 🧬Lots of chats with folks about all things bioinformatics, DNA sequencing, multiple sequence alignment and protein structure!

I am #exhilarated to share that our new paper "LIGYSIS-web: a resource for the analysis of protein-ligand binding sites" is now published in @narjournal.bsky.social! After almost two years of development and more than 600 commits, LIGYSIS-web is out! 📜 : tinyurl.com/utges-LIGYSI...

Accessing a wealth of structure data to integrate with your #MSA is possible accessing the #3DBeacons network through #Jalview. Get experimentally determined structures from @pdbeurope.bsky.social as well as predicted structure models from #AlphaFoldDB, @swiss-model.bsky.social and other providers!

Jalview@jalview.bsky.social · last yr.

🚀 Structure alert: Discover protein models in Jalview using the 3D Beacons network. Browse thousands of experimental and predicted structures from Protein Data Bank, AlphaFold, SWISS Model and more with the click of a few buttons! ▶️ Watch our instructional video: www.youtube.com/watch?v=ZBDZ...

Two weeks ago, I reached a significant #milestone my career, marking my most substantial #achievement yet. Following four and a half years of dedicated work at the University of #Dundee and a successful #PhD viva defence, I attained the title of Doctor of Philosophy in #Structural #Bioinformatics

With Jalview you can explore how genetic variants map to protein structure - directly from the multiple alignment of both coding DNA and protein sequences. Seamlessly integrate your structure viewer and dive into the molecular story of the sequence! From ACGT to 3D — Jalview takes you all the way!

Jalview@jalview.bsky.social · last yr.

👀 Visualise pathogenic variants in Jalview's protein-CDS split screen window as you map these onto your favourite 3D molecular viewer! We have PyMol, ChimeraX, UCSF Chimera and JMol available for your analyses. Watch our 'Genome to Function' video to find out how: www.youtube.com/watch?v=e/6a...

What a day this was! Filled with emotions with colleagues, friends and family present and ending a really important chapter of my life. Happy with the work we did and thankful for what Dundee, the University, the School and this excellent Division has brought to my life in the last 6 years!

Geoff Barton@gjbarton.bsky.social · last yr.

Congratulations to Javier @javierutges.bsky.social on his successful PhD viva today! @bartongrp.bsky.social

#Jalview goes the extra mile! Remember the integration with @chimerax.ucsf.edu or #PyMOL? Well, you can use these viewers to inspect #AlphaFold confidence scores #pLDDT and #PAE in multiple #sequence alignment and #structure! Multiple structure prediction confidence analysis made easy with Jalview!

Jalview@jalview.bsky.social · last yr.

💡Protein lovers - a brand NEW video exploring AlphaFold's pLDDT score in Jalview is out! Find out how you can select, hide and colour your alignments using this 3D structure prediction confidence metric. ▶️ Watch the full video here: www.youtube.com/watch?v=WVCM...

I love the @chimerax.ucsf.edu #tile view. Such an elegant and dynamic way to visualise multiple structures at the same time. Here are 32 #biological #assemblies of bovine rhodopsin #P02699 (www.uniprot.org/uniprotkb/P0...) beautifully structurally aligned and downloaded from @pdbeurope.bsky.social.

It was so great to meet the #researchers behind some of the most #novel, #relevant and #impactful work in the protein-ligand interactions field. This picture was taken a few weeks ago at the @iscb.bsky.social #3DSIG + #ELIXIR #3DBioinfo meeting at @bsc-cns.bsky.social in #Barcelona! PLIs #Avengers!

I have already submitted mine. Still months away, but I am so excited! Join us in Liverpool for a great conference!

Gonzalo Parra@gonzaparra.bsky.social · last yr.

We are getting so many great abstracts!! This year's programme will look fabulous! You can still be part of it!! There is still one more week to go to send your work to this year's 3DSIG!! Do not miss the chance!!! Submit now! t.co/gCPpDtpzD8

🧬 FAMILY PICTURE 📸 It was so nice that my #PhD #supervisor @gjbarton.bsky.social came to support me to the @iscb.bsky.social #3DSIG + #ELIXIR #3DBioinfo meeting last week in Barcelona. Mike Sternberg was there too and I managed to get the family picture I wanted. Mike was Geoff’s PhD supervisor! 🎊

It was a pleasure and honour to give a talk at the #ELIXIR #3DBioinfo + @iscb.bsky.social #3DSIG meeting last week in @upc.edu and @bsc-cns.bsky.social in beautiful #Barcelona. I presented my PhD work in the @bartongrp.bsky.social in the #SLS of #Dundee on protein-ligand interactions.

Deadline was just extended to 30th March! :)

Hajk-Georg Drost@hajkdrost.bsky.social · last yr.

Please spread the word🙏: [PhD Position in Computational Evolutionary Transcriptomics] If you are interested in doing a PhD in gorgeous Scotland on 'Why embryo development goes wrong sometimes?', please consider applying and join our wonderful team in Dundee! www.dundee.ac.uk/phds/opportu...

What a great event this was: #ELIXIR #3DBioinfo + @iscb.bsky.social #3DSIG bringing together the two communities of interest of structural bioinformatics. A great selection of speakers and posters and the best way to find out what’s going on in the field. And no better place than Barcelona to do so!

Gonzalo Parra@gonzaparra.bsky.social · last yr.

Everything comes to an end but memories remain!! We had a great 3DSIG/3DBioinfo event in "sunny" Barcelona this week!! I have enjoyed so much to help organising it & to have such great minds all together sharing science for 3 days!! Aufwiedersehen friends! For more science & friendships to come! ⭐

We’ve been benchmarking deep learning co-folding methods for protein-ligand complex prediction, leading to the creation of 🌹Runs N’ Poses🌹. Great effort by @peterskrinjar.bsky.social and @jeeberhardt.bsky.social putting this together so quickly. Please have a look, excited for community feedback!

Peter Škrinjar@peterskrinjar.bsky.social · last yr.

Excited to share our latest preprint evaluating AlphaFold3, Boltz-1, Chai-1 and Protenix for predicting protein-ligand interactions, featuring our newly introduced benchmark dataset 🌹Runs N’ Poses🌹! www.biorxiv.org/content/10.1... 🧵👇 (1/n)

👩‍🎓Last month, 60% of our YouTube audience was women. This International Women's Day, we are celebrating all the trailblazing women who watch our training videos online. 💕 Thank you for supporting our educational content! Watch here: www.youtube.com/@jalviewtrai... #IWD2025 #AccelerateAction

As my PhD journey comes to an end, I can say I have no regrets. These 6 years in the @bartongrp.bsky.social in Dundee have been an immensely enriching experience. I believe @hajkdrost.bsky.social has a spark and vision and talent and an opportunity of working with him is truly worth considering!

Hajk-Georg Drost@hajkdrost.bsky.social · last yr.

Please spread the word🙏: [PhD Position in Computational Evolutionary Transcriptomics] If you are interested in doing a PhD in gorgeous Scotland on 'Why embryo development goes wrong sometimes?', please consider applying and join our wonderful team in Dundee! www.dundee.ac.uk/phds/opportu...

PhD Thesis submission ✅ Today I submitted my PhD Thesis “Computational methods for the characterisation and evaluation of protein-ligand binding sites” achieving a significant milestone in my career and the culmination of the last 4.5 years of my life. Thanks to everyone that helped me on the way!

ELIXIR 3DBioinfo Annual General Meeting | ISCB 3DSig 2025 🧬💻BSC hosts this meeting that brings together structural bioinformatics researchers from 2 communities, 3D-BioInfo & 3D-SIG, for networking & to exchange ideas ➡Check out the agenda: www.bsc.es/ZCz