Please share! My group at @zmbp-tuebingen.bsky.social is offering a post-doctoral position (4 years). We look for a structural biologist with experience in Cryo-EM/Cryo-ET to investigate the mechanisms of host invasion by pathogenic fungi. Deadline February 28th! uni-tuebingen.de/universitaet...

Very happy to say that our work on how axonemes are generated is now available on bioRxiv: www.biorxiv.org/content/10.6... - if you’ve ever wondered how the incredibly beautiful, complex structures within motile #cilia are constructed then this is for you!

EMBL is deeply saddened by the passing of our Interim Director General Peer Bork, a pioneering scientist who left an indelible imprint on life science research in Europe and beyond. We extend our deepest condolences to his family, friends, and colleagues. www.embl.org/news/people-...

🚨 Alarm!!! 🚨 AI/ML course for microscopy image analysis!!! 🧐 In 2026 at Janelia (@hhmijanelia.bsky.social), no tuition, housing and meals provided! Isn’t that borderline unbelievable?!? 20 students, ~14 TAs and lecturers 🗓️ June 4-18 2026 ✍️ Jan 15 2026 ✍️ 🔁 pls!! www.janelia.org/you-janelia/...

Deep Learning for Microscopy Image Analysis

Topics The following will be covered extensively during lectures, exercises, and project work: Image denoising and restoration (fully supervised and self-supervised) Image translation (e.g.,

janelia.org

Highly recommend this (literally life-changing) course at the MBL to anyone who wants to do the most amazing projects as part of an incredible group of scientists from diverse backgrounds, joined by their shared passion for moving cell biology forward! Check it out at the virtual open house!

Marine Biological Laboratory@mblscience.bsky.social · 8mo ago

Interested in the MBL Physiology Course and want to learn more before you apply? Join our Virtual Open House on Tues, Jan 6, 2026 | 2–3 PM ET to meet the team, hear what the course experience is like, and get your questions answered. 🔗 Register/Join: https://go.mbl.edu/r5q

Organelles do NOT have a single uniform pH. And if you think they must, because “protons diffuse fast,” this paper is for you. A thread on why that assumption is wrong; and what we found instead. 🧵 1/n

bioRxivpreprint@biorxivpreprint.bsky.social · 8mo ago

Organelles harbour pH gradients https://www.biorxiv.org/content/10.64898/2025.12.12.694065v1

Congratulations, Julia Mahamid! Julia Mahamid receives the @dfg.de Leibniz Prize for her work on structural cell biology! #LeibnizPreis

Deutsche Forschungsgemeinschaft@dfg.de · 8mo ago

Und hier sind sie – die 10 Preisträger*innen des Gottfried Wilhelm #LeibnizPreis' 2026 – ausgezeichnet für ihre exzellenten Forschungsarbeiten und Errungenschaften in der Wissenschaft! 🏆👏 Die Verleihung der Preise feiern wir am 18. März in Berlin. Einzelheiten & Kurzprofile: sohub.io/1uv1

CryoET of symbiotic cell-cell interfaces 🦑🦠 🔗 www.biorxiv.org/content/10.1...

Ariane Briegel@arianebriegel.bsky.social · 8mo ago

CryoET of microbes inside an animal organ? Yes it’s possible! Check out our new preprint showing how we did it! What an amazing collaboration with amazing scientists who made this possible!

Anthony A. Hyman will become EMBL’s next Director General. He joins EMBL from @mpi-cbg.de in Dresden. He is also Professor of Molecular Biology @tudresden.bsky.social, and was a group leader at EMBL Heidelberg from 1993 to 1999. www.embl.org/news/people-...

Happy to see that our paper on NPC (a)symmetry inspired a newspaper article!

Alice Lebreton@alicelebreton.bsky.social · 9mo ago

Les pores nucléaires sont les portes du noyau de nos cellules. Pour réguler le trafic entre compartiments, ces portes sont orientées et sécurisées comme des postes de contrôle transfrontaliers. Comment s’organise leur assemblage dissymétrique entre une face et l’autre? www.lemonde.fr/sciences/art...

Yesterday I finally defended my PhD thesis - time to say thank you to all those who were part of this journey as mentors, collaborators, colleagues and friends!

Great work of @deglushk.bsky.social from my PhD lab @mpibp.bsky.social on how to get more information out of all the membranes you see in cryoET data!

Journal of Cell Biology@jcb.org · 9mo ago

Glushkova, Böhm, & Beck @maxplanck.de develop a publicly available computational method to measure the thickness of biological membranes in cryo-electron tomograms. Analysis of algae & human cells reveals systematic membrane thickness variations within & across organelles rupress.org/jcb/article/...

We are looking for motivated #postdocs to join the lab! Biochemistry/microbiology/cryo-EM experience? Excited by #cryo-EM/ET, #chromatin? ❄️🧬🧫 Interdisciplinary projects, top EMBL facilities! Email CV + short cover letter → svetlana.dodonova@embl.de Info about the group: www.embl.org/groups/dodon...

Lab’s first paper is out!! We show the first structures of #Asgard #chromatin by #cryo-EM 🧬❄️ Asgard histones form closed and open hypernucleosomes. Closed are conserved across #Archaea, while open resemble eukaryotic H3–H4 octasomes and are Asgard-specific. More here: www.cell.com/molecular-ce...

🔬 Applications are now open! Join MBL’s world-renowned Advanced Research Training Courses, where scientists from around the globe come together to explore new ideas, master cutting-edge techniques, and become part of a dynamic network. ➡️Apply today: go.mbl.edu/courses

Course Offerings | Marine Biological Laboratory

go.mbl.edu

Check out our preprint! With new molecular mechanisms, 140 subtomogram averages, and ~600 annotated cells under different conditions, we @embl.org were able to describe bacterial populations with in-cell #cryoET. And there’s a surprise at the end 🕵️ www.biorxiv.org/content/10.1... #teamtomo

We present multi-immersion Oblique Plane microscope (miOPM), a light-sheet platform that can be adapted to a wide range of applications, from sensitive live cell imaging to imaging organs and cleared tissues. www.biorxiv.org/content/10.1...

What could be more exciting than watching Euplotes scurry around under the microscope? How about adding some raptorial predation by supergiant cannibal cells? www.biorxiv.org/content/10.1... Video by Vittorio Boscaro. 1/n

If you are thinking about the future of structural biology, we are too! Our two cents (Jürgen Plitzko and I) just got published online here: authors.elsevier.com/sd/article/S...

How many photons are in a GFP? — more than last year, and more than you thought. Here's a simple, cheap, and practical method to break a fundamental limit in fluorescence microscopy. But it only works in light sheet!

My PhD paper is in press @cellpress.bsky.social and now online: www.sciencedirect.com/science/arti...! Contents: weird #NPCs in yeast and flies, #CLEM, in situ #cryoET and more! Made possible by the amazing @becklab.bsky.social team at @mpibp.bsky.social and collaborators! #TeamTomo

The small GTPase Ran defines nuclear pore complex asymmetry

Nuclear pore complexes (NPCs) bridge across the nuclear envelope and mediate nucleocytoplasmic exchange. They consist of hundreds of nucleoporin build…

sciencedirect.com

At EMBL Grenoble, lead an independent research group using bold, original approaches to integrate complementary structural biology methods with emerging nano X-ray imaging technologies, bridging scales and modalities to unravel molecular mechanisms. embl.wd103.myworkdayjobs.com/en-US/EMBL/d...

The Molecular Systems Biology Unit is looking for an independent research group leader in one of many different areas from integrative structural biology to synthetic biology, and from AI-driven approaches to engineering biological systems. embl.wd103.myworkdayjobs.com/en-US/EMBL/d...

We are excited to announce the first in-cell structure of a LINC complex within a native nuclear envelope at subnanometer resolution!! #In-cell cryo-ET + #atomistic MD simulations! @tomdendooven.bsky.social et al!! www.biorxiv.org/content/10.1...

The MPG is advertising directorships - powerful positions for which recruitment is usually started by them reaching out to potential candidates. Let’s hope this open call will get some great (but maybe overlooked) scientists on the candidate list and doesn’t accidentally select for oversized egos…

Max-Planck-Gesellschaft@maxplanck.de · last yr.

Director at Max Planck - a unique position! The Open Call for Expressions of Interest in Max Planck Directorships is open now and can be submitted by the 31st of October 2025. ➡️ mpg.de/directors - Please share the Open Call among potential candidates.

After 5 amazing years @pilhoferlab.bsky.social I'm starting my lab @embl.org Grenoble this November embl.org/wollweber We'll image Asgard archaea and many other strange microbes ( #archaeasky, #protistsonsky..) to understand eukaryogenesis First job ad: #teamtomo scientist!🔬❄️ tinyurl.com/2rdu2ze6

You are a scientist or an engineer (with a PhD) and you want to upskill to learn about delivering scientific infrastructure for the lifesciences (experimental or computational)? You want to work in Europe, in an internationally excellent service delivery team? ARISE2 is for you!

EMBL@embl.org · last yr.

Interested in research infrastructures career? The #ARISE2 Fellowship Programme might be right for you. MSCA funded, the programme supports STEM researchers in becoming leaders in research infrastructures, driving innovation in life sciences 🧪 🗓️ Call opening: 30 June www.embl.org/training/ari...

Beautiful cutting-edge in situ cryoET work (with very pretty figures) from the Grange lab! Great to see how the field is getting closer to doing structural work in tissues and how development in FIB technology, lift-out procedures, and correlative light microscopy contribute!

cryoEM papers@cryoempapers.bsky.social · last yr.

A generalizable and targeted molecular biopsy approach for in situ cryogenic electron tomography of vitreous brain tissue pubmed.ncbi.nlm.nih.gov/40527314/ #cryoEM

Hey optical tech dev folks: how do you do alignment? Can you outline your alignment procedures for positioning optics and verifying their correct positioning?

Cryo-EM structure of the vault from human brain reveals symmetry mismatch at its caps https://www.biorxiv.org/content/10.1101/2025.05.27.656403v1