🖤 With deep sorrow, we announce the passing of Prof. Dr. Jaime Bosch, President of the Baveno Cooperation. A brilliant scientist, inspiring leader, and dear friend. His immense legacy in hepatology will endure. Rest in peace, Jaime
Jonathan G. Stine, MD MSc, FACP
@jonathanstinemd.bsky.social
Global Clinical Program Lead – Late CVRM @AstraZeneca | Clinical Professor of Medicine @PennState | #MASH researcher | Tackling liver health through science & lifestyle | #LiverSky #MASLD #run #lift #yoga #snowboard #read #garden | views my own
The muscle–adipose–liver axis is critical, yet underrecognized, in #MASLD. Sarcopenic obesity affects ~50% with #MASLD and drives ⬆️ ASCVD and liver fibrosis. Its time to standardize definitions and intervene early: link.springer.com/article/10.1...
📢Great to write this review for Hep Comms with Matt Armstrong & @jonathanstinemd.bsky.social 💪We've covered everything you need to know about #Muscle & #MASLD - Insulin resistance - Sarcopenia - Myosteatosis - Impact of weight loss drugs - Benefits of exercise 🔗 shorturl.at/aFO1Q #LiverSky
It was an absolute delight to contribute to this high-impact work with @tom-marjot.bsky.social and @mattarmstrong95.bsky.social in which we review all things #MASLD and #Muscle! If you're looking for holiday weekend reading, look no further: journals.lww.com/hepcomm/page... @ebtapper.bsky.social
Skeletal muscle and MASLD: Mechanistic and clinical insights : Hepatology Communications
, which all converge on the liver to drive disease progression and adverse patient outcomes. This review explores the mechanistic links between skeletal muscle and MASLD, including the role of abnorma...
journals.lww.com
Choose to walk 🚶♂️ or cycle 🚲 whenever possible. It can help improve: ♥️ your heart, 😇 your mind, 🌏 and the planet. Learn more 👉 bit.ly/43eExcc #RoadSafety #BeActive
New review out! 🧬 Autophagy plays a key role in #MASLD, regulating lipid metabolism, insulin sensitivity & fibrosis. But effects vary by cell type. Precision targeting is key. Great work led by Prashant Nighot and Kofi Clarke Read here: sciencedirect.com/science/arti...
Guts for Self-Eating: Role of Autophagy in Gastrointestinal Health and Disease
Autophagy, a highly conserved cellular degradation pathway promotes cell survival via lysosomal degradation of aberrant cellular proteins and recyclin…
sciencedirect.com
Heading to the PA State Capitol tomorrow to advocate for continued funding of PA CURE program. This is critical for advancing clinical and biomedical research in PA. This investment saves lives and is even more important given the status of federal research funding. #ResearchMatters #PublicHealth
#Exercise may protect the liver by blocking ferroptosis, a key cell death pathway in #MASLD. 🏃♀️🧬 New review highlights NRF2, GPX4, and iron regulation as targets. A fresh angle for #ExerciseIsMedicine and a possible link cellular senescence pubmed.ncbi.nlm.nih.gov/40206477/
Most people haven’t heard of this test, which is available in the US. It accurately predicts Alzheimer’s (not just if there’s a risk, but when). It is modulated by exercise and likely other lifestyle factors. Here’s (almost) everything we know about it erictopol.substack.com/p/the-breakt...
Ok, I couldn't resist this trend any longer... I had to have ChatGPT make my action figure based on my bio and here is what it generated 😂 😂 😂
I join >1900 members of US National Academies of Science, Engineering, and Medicine signing this letter, as individuals, decrying the present thoughtless assault on science, which is against our national interests. docs.google.com/document/d/1... Our health, wealth, and security depend on science.
Public Statement on Supporting Science for the Benefit of All Citizens
TO THE AMERICAN PEOPLE We all rely on science. Science gave us the smartphones in our pockets, the navigation systems in our cars, and life-saving medical care. We count on engineers when we drive acr...
docs.google.com
How I will remember April Fools' Day 2025. Reckless. My heart is out for these dedicated folks at NIH, FDA and CDC www.statnews.com/2025/04/01/h...
HHS starts layoffs of thousands of workers across its agencies
Layoff notices began arriving early Tuesday for thousands of employees of HHS and its subsidiary agencies, with as many 10,000 workers potentially expected to be hit by the cuts.
statnews.com
🔥🆙 to publish alongside my pre-doc #HannahMohrMS in AP&T where we offer our 🧠🧠🧠 about time restricted feeding and #MASLD including commentary on the recently published CHRONO-NAFLD study Read the full paper here: onlinelibrary.wiley.com/doi/10.1111/...
Editorial: Chrononutrition and MASLD—Its About Time (Restricted Feeding)!
Click on the article title to read more.
onlinelibrary.wiley.com
THIS: The Best Investment You Didn’t Know You Made: How NIH Funding Fuels Innovation and Economic Growth www.amfar.org/news/how-nih...
The Best Investment You Didn’t Know You Made: How NIH Funding Fuels Innovation and Economic Growth
Continued investment in the NIH is essential to fighting current and emerging health threats and to ensuring the U.S. remains a global leader in medical innovation.
amfar.org
New paper from us in @jhepatology.bsky.social: www.journal-of-hepatology.eu/article/S016... Causes of death in >13,000 persons with #MASLD - check it out #liversky. So proud of co-senior author Axel Wester and first author medical student Gabriel Issa for the work!
Cause-specific mortality in 13,099 patients with metabolic dysfunction-associated steatotic liver disease in Sweden
Data on cause-specific mortality in metabolic dysfunction-associated steatotic liver disease (MASLD) are limited. We aimed to determine the rate and risk of death from different causes in patients wit...
journal-of-hepatology.eu
Our March member spotlight is Dr. Pooja Singhal! She discusses the critical role women #GI docs play in assisting the unique needs of female patients, her involvement in the @amergastroassn.bsky.social Women in GI Workshop & more: buff.ly/dFGqZ2d
In these unprecedented dark times for American life science and medical research (no less well beyond biomedicine), my coping mechanism is to laser focus on the unremitting and remarkable daily advances, and the fervent hope these will not be slowed or interrupted.
Join us for Penn State Health MASH Day on June 12th for a high-yield medical conference covering the latest in MASLD/MASH diagnosis and management. Don't miss expert insights and practical takeaways! Register here: ce.med.psu.edu/mash/ It’s free!
Penn State Health Metabolic Dysfunction-Associated Steatohepatitis (MASH) Day - Penn State College of Medicine Continuing Education
Penn State Health Metabolic Dysfunction-Associated Steatohepatitis (MASH) Day is a continuing education program of Penn State College of Medicine taking place in Hershey, Pa.
ce.med.psu.edu
New report shows that NIH grants fueled $95 billion in economic activity and 407,782 jobs in 2024. That's not to mention the countless lives that biomedical research has saved. Show me a better investment than that. www.forbes.com/sites/michae...
NIH Grants Fueled $95 Billion In FY 2024 Economic Activity, Finds New Report
National Institutes of Health grants generated almost $95 billion in economic activity nationwide in FY 2024 according to a new report by United for Medical Research.
forbes.com
Pretty big turnout at Stand Up for Science, talked with scientists and non-scientists who came to DC from all over.
Today is #WorldObesityDay and a good reminder that obesity is a major driver of #MASLD affecting billions worldwide. The good news? #Lifestyle interventions work! #Exercise can reverse liver fat & improve metabolic health. Let’s turn awareness into action! #ExerciseIsMedicine
Today is #WorldObesityDay. #Obesity is a complex condition and each individual faces distinct needs & challenges. A healthier society is possible only if we prioritize community support & stand up against discrimination and stigma 🔗bit.ly/3SAcdeE
"Without drastic intervention, 3·80 billion adults over the age of 25 years will have overweight and obesity by 2050." www.thelancet.com/journals/lan... @thelancet.bsky.social
Global, regional, and national prevalence of adult overweight and obesity, 1990–2021, with forecasts to 2050: a forecasting study for the Global Burden of Disease Study 2021
No country to date has successfully curbed the rising rates of adult overweight and obesity. Without immediate and effective intervention, overweight and obesity will continue to increase globally. Pa...
thelancet.com
Did you know? 1 in 8 people worldwide are living with obesity. #Obesity can lead to serious health conditions like type 2 diabetes, hypertension & cardiovascular diseases. Learn how to prevent obesity 🔗 bit.ly/3SAcdeE #WorldObesityDay
🎙️ Just finished a great interview with HCPLive on the importance of a #multidisciplinary care model for #MASLD. Collaboration across specialties is key to improving outcomes and redefining liver care! #LiverHealth #TeamApproach 📢 Full thoughts here: www.hcplive.com/view/the-imp...
The Importance of Multidisciplinary MASLD Care, with Jonathan Stine, MD, MSc
Stine explains the continued need for diet and exercise in MASH and the importance of a multidisciplinary approach to treating these patients.
hcplive.com
Presently, an estimated 60-70 million Americans are suffering from GI diseases. That is why consistent and sustainable funding from NIH is necessary to support innovative research and treatment development. Please take a minute to tell Congress to stop NIH cuts! gastro.quorum.us/campaign/109928
Tell Congress to Stop Harmful NIH Research Cuts!
Tell Congress to Stop Harmful NIH Research Cuts!
gastro.quorum.us