Genome editing in opossum embryos, a technical tour de force! Congratulations to all the authors.

Turner Lab@lab-turner.bsky.social · 4w ago

New preprint 📢 Thrilled to share our long-awaited work on the role of RSX in marsupial X-inactivation. This was a huge team effort over the years, led by @aureliencourtois.bsky.social @sermenchero.bsky.social Sugako Ogushi and Waz Varsally, that allowed us to set up genome editing in opossum embryos

Thank you @ktgarschall.bsky.social and @eudaldpascual.bsky.social for inviting me to such a nice symposium. I had a great time at #EED2026

Kathrin Garschall@ktgarschall.bsky.social · 2mo ago

Thank you #EED2026 for the exciting update on evo-devo! ✨ Super grateful to @eudaldpascual.bsky.social for cohosting and the brilliant speakers of our metabolism session! 🔥 @krittikas20.bsky.social @prhsteinmetz.bsky.social @jorgelazaro.bsky.social and Cristina Gonzalez-Estevez.

Unplanned reunion with former @embldbunit.bsky.social labmates @aliseleit.bsky.social and @jorgelazaro.bsky.social at #EED2026!!

Honoured and overwhelmed to receive the 2026 Waddington Medal. Science is a team effort, and I've been fortunate to work alongside exceptional people asking hard questions. Thank you to the BSDB and to everyone who has been part of the journey. bsdb.org/2026/03/24/2...

2026 Waddington Medal Winner - James Briscoe - BSDB - British Society for Developmental Biology

We are very pleased to announce that this year’s Waddington medal winner is James Briscoe. His fundamental discoveries have helped shape our understanding of of how morphogens work, and he has played ...

bsdb.org

I am thrilled to share our new publication in @natcomms.nature.com showing that the vertebrate developmental hourglass has a cellular basis. We asked whether this embryonic pattern is already evident at the level of cells, the building blocks of complex organisms. rdcu.be/e70XT

A cellular basis for the hourglass pattern in vertebrate embryogenesis

Nature Communications - The developmental hourglass has long been seen at the level of embryos. By zooming in to single cells, this Perspective shows that mid-embryonic conservation arises from...

rdcu.be

Thrilled to share my main postdoc work with @jamesbriscoe.bsky.social We used genomic barcoding + scRNAseq in chick & human embryos to reveal a lineage architecture that reshapes how we understand neural tube development & cell fate decisions 🧵👇 www.biorxiv.org/content/10.1...

Hierarchical lineage architecture of human and avian spinal cord revealed by single-cell genomic barcoding

The formation of neural circuits depends on the precise spatial and temporal organisation of neuronal populations during development. In the vertebrate spinal cord, progenitors are patterned into mole...

biorxiv.org

🎙️En motiu del #DiaMundialDelsAnimals, al #PRBBPodcast #LaMareDeLaCiència parlem amb @jorgelazaro.bsky.social d' @embl.org, que ha creat un petit zoo de cèl·lules mare 🧬 per entendre com es desenvolupen els embrions en diferents espècies… inclosos els humans! 🎧Escolta’l aquí 👉https://tuit.cat/y31xe

Finally .. incredible much awaited wok on deriving avian naive ESCs “Derivation of embryonic stem cells across avian species” www.nature.com/articles/s41...

Derivation of embryonic stem cells across avian species - Nature Biotechnology

Embryonic stem cells for chicken and seven other avian species are derived.

nature.com

Preprint alert! We combined microfluidics, proteomics, and RNA-seq to map spatiotemporal protein expression during mouse somitogenesis and found a novel regulatory strategy: dynamic antagonistic gradients fine-tune signalling strength. doi.org/10.1101/2025...

I'm happy to share that I recently started a postdoctoral position in the labs of @lab-turner.bsky.social and @jamesbriscoe.bsky.social at the Francis Crick Institute. Stay tuned for some marsupial development!

In preprints: robust segmentation clock outputs via cell cycle and synthetic coupling Here, @jorgelazaro.bsky.social and @ebisuyamiki.bsky.social discuss two #preprints looking into the mechanisms regulating somitogenesis through cell- and tissue-level couplings: doi.org/10.1242/dev....

Jorge and I wrote an introductory article highlighting two HOT new preprints on the segmentation clock!

Jorge Lázaro@jorgelazaro.bsky.social · last yr.

In this "In preprints" piece, we highlight recent work from the @sonnenlab.bsky.social and Kageyama labs exploring novel mechanisms and tools involved in cell- and tissue-level couplings during somitogenesis. Congrats to the authors! @dev-journal.bsky.social doi.org/10.1242/dev....

In this "In preprints" piece, we highlight recent work from the @sonnenlab.bsky.social and Kageyama labs exploring novel mechanisms and tools involved in cell- and tissue-level couplings during somitogenesis. Congrats to the authors! @dev-journal.bsky.social doi.org/10.1242/dev....

In preprints: robust segmentation clock outputs via cell cycle and synthetic coupling

The segmented body plan of vertebrates becomes apparent during development, when two bilaterally symmetrical rows of somites emerge along the body axis. This process, known as somitogenesis, occurs se...

doi.org

Thrilled to announce that I am looking for a Research Technician/Assistant to join my lab @imbavienna.bsky.social. Please consider applying if you’re enthusiastic about #devbio #stemcells #teamwork and excited to help shaping a new lab! Thankful for any retweet! 🫶 imba.onlyfy.jobs/job/l6u2m980

Research Technician

IMBA - Institute of Molecular Biotechnology is one of the leading biomedical research institutes in Europe focusing on cutting-edge functional genomics and stem cell technologies. IMBA is located at t...

imba.onlyfy.jobs

Institute of Molecular Biotechnology@imbavienna.bsky.social · last yr.

We are hiring! Join the Stapornwongkul Lab as a Research Technician and investigate the tissue scale organization of metabolic processes and their impact on developmental processes. Apply using the link below.

Great opportunity and amazing mentor. Do not think twice!

Kristina Stapornwongkul@kstapornwongkul.bsky.social · last yr.

We’re looking for PhD students to join the lab! 🧫🧑‍🔬 Curious about how metabolic processes shape patterning and morphogenesis? Enthusiastic about stem cell models for human development? - Then apply through the VBC PhD program! training.vbc.ac.at/phd-program/ ‼️Deadline: April 15‼️

We’re looking for PhD students to join the lab! 🧫🧑‍🔬 Curious about how metabolic processes shape patterning and morphogenesis? Enthusiastic about stem cell models for human development? - Then apply through the VBC PhD program! training.vbc.ac.at/phd-program/ ‼️Deadline: April 15‼️

Latest work: Review on the evolvability of vertebral number, and the developmental processes underpinning it Written by Callum Bucklow, @bertaverd.bsky.social, and myself Check it out here: doi.org/10.32942/X2K...

Kristina Stapornwongkul is joining IMBA! The Stapornwongkul lab will study how the nutritional environment and metabolic processes influence embryonic development—an emerging research area with broad implications for both fundamental biology and biomedical applications. Welcome, Kristina!

Incredible news! Congrats Kristina!

Kristina Stapornwongkul@kstapornwongkul.bsky.social · last yr.

Amidst these troubling times, I have some positive personal news to share: I will be joining @imbavienna.bsky.social as a new group leader this fall! 🎉 I am excited for fun projects, surprising discoveries, and great discussions within the fantastic science community @vbcscitraining.bsky.social

Very happy to see this out. We observed that different metabolic pathways act as selective modulators of developmental tempo instead of affecting it globally. Congrats to Mitsuhiro for all the hard work!

Miki Ebisuya@ebisuyamiki.bsky.social · 2y ago

Latest from the lab! I've been seeking the ultimate modulator that regulates the tempo of multiple developmental processes simultaneously, and metabolism has been an attractive candidate for such a global tempo modulator. However, I was wrong. 1/ www.nature.com/articles/s41...

We thrilled to see our latest study led by @jeremie-subrini.bsky.social now out in @science.org 🔬 What are the specific functions of each Y-chromosome gene in fertility ? We generated and studied 13 Y-gene KO mouse models to find out! 🧬 www.science.org/doi/full/10....

We wrote this for the #SpemannMangold organiser centennial meeting #Freiburg 🙏 It is about whether early embryos should be on top 👆or at the bottom👇of the #hourglass🤔(and other issues)🤓 #InHoxWeTrust 🤟https://pegasus.epfl.ch/?03a82edc91bc5cc1#EKvX77Spd79oMYaisF5hwHBkts6XcGcVnRRDhd5pHNrJ

Thorough study comparing the vertebral formula of more than 388 tetrapod species. The relationship between Hox expression and vertebral identity is not trivial, specially in birds. www.pnas.org/doi/10.1073/...

Please read and share this ⬇️ journals.biologists.com/dev/article/...

The case against simplistic genetic explanations of evolution

Summary: Extreme traits in animals, from the origin of limbs to the loss of tails, capture public attention. This Review argues that scientists should not seek simple explanations for how they evolved...

journals.biologists.com

My first post on @bsky.app. So happy to announce that our work has been published in Development by @biologists.bsky.social doi.org/10.1242/dev.... Also a big thanks for "The people behind the papers" article as well! doi.org/10.1242/dev....

2nd edition of the EMBO Workshop on Dev timing & evolution will take place in Paris. 6-9 May 2025. Save the date!!! coming-soon.embo.org/w25-105

Thanks to the Ebisuya lab for such a wonderful PhD defense celebration!