What if the segmentation clock does more than tell an embryo when to make a segment? In our new paper in @cp-devcell.bsky.social, we show that it also helps coordinate tissue growth with segmentation, promoting robust somite formation! 🧵👇 www.cell.com/developmenta...

I so appreciated Marta’s positivity, enthusiasm, and initiative, and the way she brought people along and helped shape the field. I will miss her dearly.

Jesse Veenvliet@jesseveenvliet.bsky.social · 4d ago

The @sonnenlab.bsky.social discovered a functional role for oscillation frequencies in keeping the gut cells in balance. They experimentally changed the frequency of Hes1 oscillations in intestinal organoids and showed that this altered cell-type composition.https://www.hubrecht.eu/cells-got-rhythm/

🎉 Our paper is out today in @science.org! How does the intestine maintain the right balance of cell types? We find that signalling rhythms matter! So proud of our three shared first authors, Sonja Weterings, @hiromuneeto.bsky.social & @jddeleede.bsky.social! 🔗 www.science.org/doi/10.1126/...

Funded places are available for early-career researchers at our Workshop on Bridging Scales and Disciplines to Understand Robust Development, 18-21 April 2027, organised by Mauricio Rocha Martins and Giulia Paci @giuliapaci.bsky.social Find out more and apply at www.biologists.com/workshops/ap...

I’m starting at the Hubrecht Institute at a new group leader from September. I will be hiring a PhD student through the PhD program ⬇️ If you, or anyone you know, is interested in theoretical biophysics, I will be very excited to hear from them — please send inquiries to my ISTA email for now :)

Hubrecht Institute@hubrechtinstitute.bsky.social · 3mo ago

Are you excited to redefine our understanding of molecules, cells, tissues and organisms? Then we are looking for you! Applications for the Hubrecht International PhD program (HIPP) are now open and will be accepted until September 15th. Read more here 👉 www.hubrecht.eu/hipp/

Funded places are available for early-career researchers at our Workshop on Bridging Scales and Disciplines to Understand Robust Development, 18-21 April 2027, organised by Mauricio Rocha Martins and Giulia Paci @giuliapaci.bsky.social Find out more and apply at www.biologists.com/workshops/ap...

There's still time to apply to be a 2026 @dev-journal.bsky.social Pathway to Independence fellow For those about to apply for their first independent academic position, the programme offers - mentoring - leadership training - profile rising - networking journals.biologists.com/dev/pages/pi...

Feb 1 deadline approaching for our @kitp-ucsb.bsky.social QBio summer course on Physical Principles of Morphogenesis in Plants and Animals. @streichan.bsky.social @maurazimmermann.bsky.social @maizel-lab.org @yusuke-mori.bsky.social @akankshi.bsky.social @nicolettapetridou.bsky.social

⏰ Deadline extension for #EESBioOsc ⏰ You now have until 14 January to submit your abstract for the EMBO | EMBL Symposium 'Biological oscillators: rhythms and synchronisation across scales'! 👉 s.embl.org/ees26-04-bl

Using fluorescence live imaging and an in vitro implantation model, we show that human embryo attachment begins with direct cell fusion via syncytin-2–MFSD2A interaction. With @hansclevers.bsky.social. Great work by @tnoordzij.bsky.social & @martinacelotti.bsky.social www.biorxiv.org/content/10.6...

Incredibly excited to receive an ERC Consolidator Grant. This recognition means a lot for what we’ve built so far and for what’s ahead. Thank you to all collaborators and supporters. Looking forward to getting this project going!

Hubrecht Institute@hubrechtinstitute.bsky.social · 11mo ago

Congratulations Ina Sonnen on receiving a Consolidator Grant from @erc.europa.eu! It will allow her to strengthen her research group and take on questions such as: how do cells communicate robustly and precisely with each other during development, despite noise? Read more👉 www.hubrecht.eu/erc-sonnen

Don’t miss the @isscr.org Annual Meeting 2026 in Montreal. I will give a talk in the “Systematic and metabolic regulation of development” session. #ISSCR2026 www.isscr2026.org?gad_source=1...

Huge congrats to Dr. Sonja Weterings! Yesterday Sonja from my lab @hubrechtinstitute.bsky.social delivered an outstanding PhD defense. Her thesis explores how frequency encoding shapes cell type composition in the intestine. We’re so proud of her, and we’re going to miss her!

Hubrecht Institute@hubrechtinstitute.bsky.social · 11mo ago

Today, Sonja Ruttchen Weterings successfully defended her PhD thesis! She investigated how the timing of molecular signals influences cell renewal in the small intestine. Congratulations Sonja! 🎓 www.hubrecht.eu/phd-ruttchen-weterings

Ready to establish your own research group at the Hubrecht Institute for Molecular and Developmental Biology? We’re seeking a tenure-track group leader to develop an innovative research line within our vibrant scientific community. Learn more & apply! https://f.mtr.cool/jncxfqkuds

Preprint alert! We combined microfluidics, proteomics, and RNA-seq to map spatiotemporal protein expression during mouse somitogenesis and found a novel regulatory strategy: dynamic antagonistic gradients fine-tune signalling strength. doi.org/10.1101/2025...

Just one month left to apply for the Hubrecht International PhD Program! This fully funded 4-year PhD offers the opportunity to join a high-profile lab in molecular & developmental biology, exceptional training, and mentorship from leading scientists. Apply before September 15 www.hubrecht.eu/hipp/

Please pread the word. We have just launched the Hubrecht International PhD Program (HIPP). Are you looking for a PhD position in molecular and developmental biology or related subject in an international, very supportive and collaborative environment? Then apply to the HIPP!! 👇

Hubrecht Institute@hubrechtinstitute.bsky.social · last yr.

🧬 Looking for a PhD position in molecular or developmental biology? 🔬 ✉️ The Hubrecht Institute now has its very own PhD program! Applications are open and will be accepted until September 15th. Read more here 👉 www.hubrecht.eu/hipp/

Thank you for the kind words and highlighting this milestone. I’m thrilled and honoured to have reached tenure. Big thanks to my lab, colleagues, mentors, friends and family who’ve supported me along the way. Excited to keep doing what I love - now with slightly more security.

Hubrecht Institute@hubrechtinstitute.bsky.social · last yr.

What if science is like solving puzzles? We spoke with @sonnenlab.bsky.social, a group leader who recently received tenure. She tells us about her journey, her research on signaling dynamics, and the challenges of leading a lab. Read her inspiring story here 👇 www.hubrecht.eu/ina-sonnen-t...

It was fun reflecting on how my career path took me from a focus on cancer research to developmental biology, the urge to understand how development and tissue homeostasis work and how my time at the @biozentrum.unibas.ch contributed to this. Thank you, Katrin Bühler-Popowski, for the interview!

Biozentrum, University of Basel@biozentrum.unibas.ch · last yr.

Since she was a child, Ina Sonnen dreamed of becoming a cancer researcher. Although her academic career took a slightly different path, the topic of cancer has never quite left the Biozentrum alumna. @sonnenlab.bsky.social ‪ @hubrechtinstitute.bsky.social www.biozentrum.unibas.ch/about/alumni...

W2 TT W3 professorship in the Dynamics of Biological Systems at @uni-saarland.de - only a few days left to apply! (June 13) www.uni-saarland.de/fileadmin/up...

Morgan Lab@morganlab-saarland.bsky.social · 2y ago

We are looking for a new colleague in the biology department at Saarland University! We are looking for excellent Cell Biologists / Cell Physiologists for a W2 tenure track W3 professorship in 'Dynamics of Biological Systems'. Please share! jobs.zeit.de/jobs/w2-prof...

Delighted that our work on positional memory is now published. We asked how axolotl cells 'know' which part of the limb to regenerate after injury. www.nature.com/articles/s41... A joy to work with super team Sarah Plattner, Yuka Sugiura, Francisco Falcon and Elly Tanaka. 🧵1/14

I am just on my way to Switzerland and looking forward to a fun and exciting day at the Institute of Cell Biology in Bern tomorrow.

Institute of Cell Biology@izb-unibern.bsky.social · last yr.

📢Seminar Announcement 📢 We're looking forward to welcoming @sonnenlab.bsky.social this upcoming Monday, May 19th, as the next speaker in our Monday Seminar Series! She will discuss "Signalling dynamics in embryonic development and tissue homeostasis” More info on our website ➡️ izb.unibe.ch

Thoughtful preview article by María Rodríguez Colman & @sonnenlab.bsky.social on recent papers from our lab and @jesseveenvliet.bsky.social lab! Grateful for their in-depth analysis of the papers and their big-picture perspective on the role of metabolism in development. doi.org/10.1016/j.st...

Signaling switches: Metabolism regulates gastruloid self-organization

Metabolic regulation of embryonic development is increasingly recognized. Villaronga-Luque et al. and Stopornwongkul et al. show that metabolic activity influences gastruloid formation from mouse embr...

cell.com

In preprints: robust segmentation clock outputs via cell cycle and synthetic coupling Here, @jorgelazaro.bsky.social and @ebisuyamiki.bsky.social discuss two #preprints looking into the mechanisms regulating somitogenesis through cell- and tissue-level couplings: doi.org/10.1242/dev....

Thanks for featuring my work with @sonnenlab.bsky.social and @marekvanoostrom.bsky.social in this thoughtful article!

Development@dev-journal.bsky.social · 2y ago

In preprints: robust segmentation clock outputs via cell cycle and synthetic coupling Here, @jorgelazaro.bsky.social and @ebisuyamiki.bsky.social discuss two #preprints looking into the mechanisms regulating somitogenesis through cell- and tissue-level couplings: doi.org/10.1242/dev....

We challenged our researchers to describe their work in 10 words or less. See how they did in this video!

Thank you for highlighting our preprint on the coordination between cell proliferation and the segmentation clock www.biorxiv.org/content/10.1...

Coupling of cell proliferation to the segmentation clock ensures robust somite scaling

While scaling developmental processes is fundamental to maintaining robust tissue patterning, the mechanisms underlying this process are enigmatic. Somitogenesis, the periodic segmentation of growing ...

biorxiv.org

Jorge Lázaro@jorgelazaro.bsky.social · 2y ago

In this "In preprints" piece, we highlight recent work from the @sonnenlab.bsky.social and Kageyama labs exploring novel mechanisms and tools involved in cell- and tissue-level couplings during somitogenesis. Congrats to the authors! @dev-journal.bsky.social doi.org/10.1242/dev....

Well done @virginiar-andra.bsky.social from our lab for being awarded the Best Poster Prize at the International Dutch Embryo Model Meeting today for our work on “Spatiotemporally resolved omics reveals dynamic antagonistic gradients” in embryo segmentation. Congratulations!

Moritz Bauer@moritzbauer.bsky.social · 2y ago

📢 Save the date! We are excited to announce the International Dutch Embryo Model Meeting 2025 in Nijmegen (NL) on Thursday 27 March and Friday 28 March! Registration is open now. More information: ru.nl/en/about-us/... Big thanks to Hendrik Marks for taking the lead this time!

And what a talk that was!