What is the public opinion on color coding treatments in figures and then using the same colors used in the graph to outline matching representative images? Is it useful or am I being too extra?

I collaborated with Peter Friedl's team, @jpassmore.bsky.social and @ekatrukha.bsky.social to make this short video on cancer cell invasion. Check it out! youtu.be/EH4vgUfr1jI?...

Invasion and Metastasis - How cancer cells become invasive

YouTube video by IMAGINE! microscopy

youtu.be

Good morning to everyone except people who write "as described previously" in their paper and then cite another paper that doesn't describe the procedure. 🫠

Tools to optically & chemically manoeuvre cytoskeleton structures intermediate filaments reveal their characteristics & interactions 📷 Milena Pasolli & @joycemeiri.bsky.social et al @utrechtuniversity.bsky.social in @jcb.org ➡️ bpod.org.uk/archive/2026... with @antdlewis.bsky.social

If you have time tomorrow, join my online talk about LLS/single molecule/microtubules and 3D data at @bioimagingna.bsky.social user group (18:00 CET for Europe). I hope I manage to fit 25 movies into 20 cohesive slides and connection will be ok.

BioImaging North America@bioimagingna.bsky.social · 7mo ago

#HappyMicroscpyMonday #microscopycommunity - Join us tomorrow, Tue Jan 6 for a talk by Eugene Katrukha on "Single molecule imaging using LLS7", hosted by the BINA Lattice Lightsheet User Group Learn more & register here: buff.ly/US5Xd2q

Thanks for highlighting our most recent preprint 😊

preLights@prelights.bsky.social · 7mo ago

Two more recent preLights were written by Vibha Singh @vibhasingh.bsky.social 🙌 One that discusses Taxane-induced conformational changes in the microtubule lattice. #preprint from Joyce Meiring @joycemeiri.bsky.social and colleagues #UniUtrecht. #preLight ⬇️ prelights.biologists.com/highlights/t...

Taxane-Induced Conformational Changes in the Microtubule Lattice Activate GEF-H1-Dependent RhoA Signaling https://www.biorxiv.org/content/10.64898/2025.12.20.695343v1

Bored over the holidays? Give our new preprint on how #microtubule lattice alteration by taxols can regulate #RhoA #signalling via GEF-H1 a read! Perhaps a new mechanism of action for taxol #chemotherapeutics during interphase. www.biorxiv.org/content/10.6... Happy holidays ✨🎄

A cell finding its way through the matrix, imaged with @joycemeiri.bsky.social on LLS.

Our new preprint is about the airway epithelium microtubule network, cilia, basal body protein composition, averaging of volumetric fluorescence data, and expansion microscopy. Four years of very hard work from our very talented Emma van Grinsven. www.biorxiv.org/content/10.1... (1/N)

Our September issue is here! rupress.org/jcb/issue/22... Airyscan super-resolution immunofluorescence image of HeLa cells stained for two types of intermediate filaments: vimentin (magenta) & keratin-8 (cyan). From Pasolli, @joycemeiri.bsky.social, Akhmanova et al. rupress.org/jcb/article/...

All the opto-vimentin plasmids are now available on Addgene: www.addgene.org/Anna_Akhmano...

Joyce Meiring@joycemeiri.bsky.social · last yr.

Excited to share that our fast & reversible chemical and optogenetic vimentin pulling tools are now published in JCB! 🥳 We show a subset of organelles are displaced with vimentin pulling to the cell centre and cells become much softer despite little or no effect on actin/MTs doi.org/10.1083/jcb....

Radial microtubules in cyan and non-radial microtubules in yellow.

Biomedical Picture of the Day BPoD@bpodaily.bsky.social · last yr.

Biochemical tools to rapidly manipulate vimentin intermediate filaments by means of chemicals or light (optogenetics) 📷 Milena Pasolli & @joycemeiri.bsky.social et al ‪@utrechtuniversity.bsky.social in @jcb.org ➡️ bpod.org.uk/archive/2025...

Optogenetic and chemical genetic tools for rapid repositioning of #vimentin intermediate filaments. New tools developed by Milena Pasolli, Joyce Meiring @joycemeiri.bsky.social, Anna Akhmanova and colleagues @utrechtuniversity.bsky.social: rupress.org/jcb/article/... @gijsjekoenderink.bsky.social

New: Pasolli, Meiring, Akhmanova et al. @utrechtuniversity.bsky.social describe tools to acutely relocate #vimentin intermediate filaments by inducibly coupling them to microtubule motors. rupress.org/jcb/article/... @joycemeiri.bsky.social @gijsjekoenderink.bsky.social #Technology #Cytoskeleton

Excited to share that our fast & reversible chemical and optogenetic vimentin pulling tools are now published in JCB! 🥳 We show a subset of organelles are displaced with vimentin pulling to the cell centre and cells become much softer despite little or no effect on actin/MTs doi.org/10.1083/jcb....

Thrilled to share our latest preprint from @yiechanglin.bsky.social & @ciarawallis.bsky.social showing that AF2-Multimer and AF3 can quickly & accurately predict the oligomeric states & structures of proteins (& maybe can identify multiple biologically relevant oligomeric states 👀) tiny.cc/oligomers

Don't forget to register, abstract submission deadline is next week March 14. 😉

Joyce Meiring@joycemeiri.bsky.social · 2y ago

Come join us in Utrecht for some cutting edge #microscopy and 3D cell biology!! #3Dcellbio

Is this an animated Jackson Pollock painting or live cell tracking movie? 😍

Come join us in Utrecht for some cutting edge #microscopy and 3D cell biology!! #3Dcellbio

Hi! I was wondering if anyone had successfully cultured happy HEK293T cells in defined serum alternatives? If so, what did you use?

Excited to share our new pre-print showcasing tools (chemical & optogenetic) for repositioning Vimentin in cells! Movie shows ER (Halo-KDEL) sheets being relocalized together with vimentin (Vim) upon local vimentin pulling in U2OS. @gijsjekoenderink.bsky.social www.biorxiv.org/content/10.1...

Time to shine for intermediate filaments! An optogenetic vimentin perturbation strategy reveals its role for ER and mitochondria positioning (but no effect on actin or microtubules patterns) @joycemeiri.bsky.social www.biorxiv.org/content/10.1...

Christophe 🔬 Leterrier@christlet.bsky.social · 2y ago

intermediate filaments be like

CAMSAP3 stretches (microtubule -end binding protein) are shown in yellow. They move towards the Soma in developing neurons.

Max Schelski@maxschelski.bsky.social · 2y ago

Hi! I'm Max. I'm developing a #biophysical model of #microtubules in #neurons during #development. The model is based on my surprising experimental finding (lots of live-cell imaging) that the entire microtubule array in neurites flows retrogradely into the soma: www.science.org/doi/10.1126/... 🧪 🧠📈

Hi! My name is Joyce and I love building and using tools to manipulate the #cytoskeleton of cells to better understand their function. 🔬 Below you can see my movie of #opto-katanin ✂️(SspB-mCh-p60) being used to locally disassemble #microtubules (labelled by SiR-tubulin) inside a neuron.