Kathrin Leppek

@katleppek.bsky.social

Prof TT Uni Bonn & University Hospital Bonn | RNA & ribosome & biochemistry & innate immunology | Postdoc Barna Lab Stanford | PhD Stoecklin Lab DKFZ ZMBH Uni Heidelberg | triplet | https://www.leppeklab.org

Protein synthesis is one of the most energy-intensive & highly regulated processes in biology, yet its role as a dynamic driver of cellular and organismal function remains underexplored. Join our #TCCO conference, to share research & collaborate to answer big questions in the field. bit.ly/4wkNzBU

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I was happy to present our collaborative Early Career Award project at the HFSP Awardee Meeting in Geneva this week! And meeting up with my collaborator Drago Milovanovic and getting to know so many other awardees across such diverse disciplines. #HFSPmtg2026

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Human Frontier Science Program@hfspo.bsky.social · 4w ago

What does frontier science look like? 🧪 At #HFSPmtg2026, it spans everything from cell migration and photosynthesis to evolution, plant biology or ocean microbiomes. Different questions. Different approaches. One community exchanging ideas across disciplines! 💪 #HFSP #sts

Three days of inspiring science, lively discussions, poster sessions, new collaborations, and a global community brought together by frontier life science.🧪 A big thank you to everyone who made this year's Awardees Meeting such a success. 🙂 Until next year!🙃 #HFSP #sts

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We're delighted to announce a brand new meeting series, joining the Fusion community in May 2027. *Translational Control - From Cells to Organisms Conference* 📅Date: 22 - 25 May 2027 🌏Location: Durrës, Albania Sign up for updates to find out more information on the conference: bit.ly/4eGxaQG

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How do fictions and models shape our understanding of existence? Join IMPULSE-Focus “Imagination” with Hans Ulrich Gumbrecht: a public lecture on 9 June and an experimental workshop on 10 June with colleagues from across disciplines. © Ulrike Syrakas/IMPULSE Bonn

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’m thrilled to share that our paper is out in Molecular Cell! We developed Ribo-Tweezer, a new technology that lets us rapidly and reversibly remove specific proteins from mature ribosomes to ask what they actually do in translation.

NEWS: The ERC Scientific Council has listened to the concerns from members of the research community about changes to the re-submission rules, intended to manage the surge in demand for grants. The Scientific Council will readjust some of the changes: link.europa.eu/TBqRQJ

ERC Scientific Council readjusts rules for reapplication

The ERC Scientific Council has listened to the concerns from members of the research community about the recent announcement on changes to the re-submission rules. The changes, intended to manage the ...

link.europa.eu

The number of grant applications is rising sharply. Our capacity for their evaluation isn’t. ERC President Maria Leptin explains why stricter resubmission limits are being introduced for 2027 calls and what they mean for applicants. 🔗 link.europa.eu/xF7kjc

ERC President explains stricter application measures amid rising demand for funding

The text of an open letter sent by ERC President Maria Leptin to ERC panel members, grantees and other stakeholders on 16 April 2026.

link.europa.eu

How could a simple self-replicating system emerge at the origins of life? RNA polymerase ribozymes can replicate RNA, but existing ones are so large that their self-replication seems impossible. Could they be smaller? Excited to share our latest work in @science.org on a new small polymerase. 1/n

A small polymerase ribozyme that can synthesize itself and its complementary strand

The emergence of a chemical system capable of self-replication and evolution is a critical event in the origin of life. RNA polymerase ribozymes can replicate RNA, but their large size and structural ...

science.org

We had a great day at the 1st RNA Confluence Meeting of Rhine-Main-Neckar region German RNA Clubs(+Strasbourg) with 200 attendees & trainee talks at EMBL Heidelberg yesterday. Particularly proud of Sam and Philipp taking home 2 poster prizes (of 100 posters)! 🎉 🐙 Special thanks to Alessia and Venki!

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I got blocked by ChatGTP twice in one hour. Yes, I want to target RNA structure, that is my job. No, I do not want to harm people nor design a super virus bioweapon. While I should probably be happy this safety check is in place, I happily dive into the literature myself...