Kellie Machlus
@kmachlus.bsky.social
I research hematopoiesis and how megakaryocytes make platelets 🩸🔬 Associate Professor at Harvard Medical School and Boston Children’s Hospital 🏳️🌈 she/her #medsky #scisky #hematology
So fun to be a part of this groundbreaking work led by @bloodgenes.bsky.social
Vijay G. Sankaran@bloodgenes.bsky.social · 4mo ago❓A one-time, durable, and even reversible way to prevent thrombosis? In this preprint, led by @lrbzldz.bsky.social, we show that epigenome editing of 🩸 #StemCells can durably reprogram platelet function: www.biorxiv.org/content/10.6...
Powerful piece in STAT this morning from some NIH staff members who have resigned www.statnews.com/2026/01/10/n... 1/3
The NIH has lost its scientific integrity. So we left
“We can no longer lend our credibility to an organization that has lost its integrity,” write four scientists and administrators who recently resigned from the NIH.
statnews.com
Join us to pursue cutting-edge research at the interface of megakaryocyte biology and translational medicine. We have NIH-funded postdoc positions available to investigate platelet production and the broader functions of megakaryocytes. I’ll be attending ASH and would be happy to connect.
Excited for this session! If you’re at #AHA25 today, please join us!
@hanrui-zhang-clear.bsky.social · 9mo agoPlanning for Day 1 of #AHA25? Join VB.CVS.04: Keep It Simple – Cutting-Edge Vascular, Lipid, and Coagulation Research: 📅 Friday, November 7 | 12:30–1:45 PM 📍 Rivergate – 1st Floor of the Convention Center ⚡️ Fast and focused updates tailored for both researchers and clinicians.
A little known - but hugely consequential - part of the government’s changes to science funding: open.substack.com/pub/sciencea...
A Quiet Policy Shift That Could Devastate American Science
Why NIH’s sudden move to multi-year grant funding should alarm every principal investigator and university
open.substack.com
So well put. Something I am thinking about every day with research as well.
Jeremy Yoder says no war@jbyoder.org · last yr.“I was once so compelled by medicine’s commitment to the worth of each human life that I set out to live by it. Now I know that a doctor’s ability to fulfill this commitment—to live a moral life in medicine—depends on the systems of care that we as a society build.” www.newyorker.com/news/the-led...
Now is a the time to get involved in your scientific societies. #Hematology #HemeSky @ash.hematology.org is stepping up for Hematology - HOW CAN YOU HELP? If you want to be on a committee nominate yourself or someone else below. I am also happy to nominate you, so just reach out. Deadline May 31!
American Society of Hematology@ash.hematology.org · last yr.ASH seeks passionate members to shape the future of hematology. Nominate yourself or a colleague for an ASH committee and help drive the Society’s mission forward. Submit today: www.hematology.org/a... 📅 Nominations due: May 31, 2025 #Leadership #Hematology #MedSky #HemeSky
This is where we are living. www.cnn.com/2025/03/25/b...
Florida debates lifting some child labor laws to fill jobs vacated by undocumented immigrants | CNN Business
Florida has been working for years to crack down on employers that hire undocumented immigrants. But that presented a problem for businesses in the state that are desperate for workers to fill low-wag...
cnn.com
The information I am receiving is consistent with the STAT story. The boards are being purged of women and minoritized scientists with no other obvious pattern. And for the cases where I have some information, the effects are not subtle...Boards going from 35% women to 10% women. 3/n
The FDA just cancelled a meeting to select flu strains for next season's flu shots. "It's unclear what the canceled meeting will mean for Americans who want to get a flu vaccine next season." www.nbcnews.com/health/healt...
FDA cancels meeting to select flu strains for next season's shots
The canceled meeting comes just days after a CDC vaccine advisory committee meeting was abruptly postponed.
nbcnews.com
The City of Boston is leading 40+ mayors, cities, and counties in an amicus brief against the Trump Administration's drastic and illegal cuts to federal research funding—cuts that will lead to immediate job losses nationwide.
The Trump administration blocked key parts of the federal government’s apparatus for funding biomedical research, effectively halting progress on much of the country’s future work on illnesses like cancer and addiction despite a federal judge’s order to release grant money.
Trump Administration Stalls Scientific Research Despite Court Ruling
Using an arcane law, officials have effectively delayed funding from the National Institutes of Health, leaving medical studies in jeopardy.
nytimes.com
Ok scientists & those who love science 🧪: here is another exhortation. Call Congress TODAY about the freeze on NIH Council Meetings and Study Sections. Emphasize that this means NO new grants are being funded & labs will soon start to shut down and fire employees. Phone numbers are at: 5calls.org
5 Calls
Spend 5 minutes. Make 5 calls. Make your voice heard.
5calls.org
Almost all grant-review meetings under Trump 2.0 remain suspended at the US National Institutes of Health (NIH), preventing the world’s largest public funder of biomedical research from spending much of its US$47 billion annual budget. https://go.nature.com/4gM6oW4
Revealed: NIH research grants still frozen despite lawsuits challenging Trump order
The Trump administration is exploiting a loophole to keep a funding freeze in place, leaving researchers in limbo.
go.nature.com
This is a red alert for US science, for new cures & treatments for diseases that afflict everyone in this country. This isn't "oh, it will blow over." Soon we will have reached the point of no return destroying what it has taken decades to build. WE NEED TO BE BANGING DOWN THE DOORS IN CONGRESS.
Dr. Becca@docbecca.bsky.social · last yr.If the block on the Federal Register isn’t removed in the next few months, I fear a majority of labs will close within a year. This small procedural wrench has the power to kill US science indefinitely, losing an entire generation of discovery and innovation.
Study section freeze hits NIH
Science Magazine@science.org · last yr.A freeze on meetings of expert panels that peer review grant proposals at the National Institutes of Health is kicking in this week. Follow Science’s coverage of President Donald Trump’s impact on U.S. research and science globally. ⬇️ scim.ag/40XtSSi
A large portion of grants awarded by the U.S. National Institutes of Health cannot be funded for the foreseeable future because of an indefinite hold on submissions to the Federal Register, according to an email reviewed by The Transmitter. By @avaskham.bsky.social bit.ly/3X8ngz8
Federal Register hold makes ‘end run’ around court pause on NIH funding freeze
NIH-related updates to the Federal Register, which are required for the scheduling of study sections and advisory councils, are on hold indefinitely, according to an email reviewed by <i>The Transmitt...
thetransmitter.org
Current inspiration as I continue doing my science as a form of protest and resistance. 🧪🩸💪
This is the most relevant article to NIH and research cuts I’ve seen. Imagine if this was today , how many people would be saying “Why are we studying Gila Monsters and their impact on diabetes ? That’s wasted money !” globalnews.ca/news/9793403...
How a Canadian scientist and a venomous lizard helped pave the way for Ozempic - National | Globalnews.ca
In 1984, Dr. Daniel Drucker, an endocrinologist from the University of Toronto, discovered a hormone that helped pave the way for popular diabetes drugs such as Ozempic.
globalnews.ca
There’s no argument that should reassure anyone enough to go back to business as usual, because none of these actions are happening in isolation. The war on US science won’t end with a court order on indirects.
Thinking back on all this I better understand the pain I feel to see science under devastating attack here. It’s not just about my livelihood or my university. It’s about my identity. And it’s about a pursuit that I see as standing along with art, literature, and music as among our highest callings.
Do it. I mean, it worked out pretty well for me ... 🙃🩸🫶
Joe Italiano@megaman55.bsky.social · last yr.Envision yourself as a member of this team? Come join our group to pursue research at the interface of megakaryocyte biology and translational medicine. NIH-funded post-doc positions available to study platelet production and the other functions of megakaryocytes.
This was so much fun to do with @aswolberg.bsky.social and @gbarnesmd.bsky.social - a chat with two great friends 🥰 Isn't that why we love this community? Great science and great people.
International Society on Thrombosis and Haemostasis@isth.org · 2y agoNew Pulse episode alert!🎙️ How do you go from mentee to mentor—and then collaborator? 🤝In today's episode, we chat w/@aswolberg.bsky.social & @kmachlus.bsky.social about the power of mentorship, building community, and finding your niche in science. @gbarnesmd.bsky.social 🎧Tune in: bit.ly/3Q3Q6wI
Hi friends. This is hard. Remember, you’re not alone- there are so many of us here that care a lot and aren’t giving up. Don’t stop talking and don’t let them make you hard. Reach out to someone that needs some encouragement. We are here ❤️ #sciencesky
We are hiring 😀 Postdoctoral position – Stem cells, Cancer, and Aging We study cell fate decision and lineage specification in hematopoietic stem and multipotent progenitor populations to modulate lineage output for therapeutic purpose in diseases and aging contexts.
Stem cell-like states confer poor outcomes in blood cancer—but what mechanisms drive this and how can they be therapeutically targeted? In our new preprint, we show how a single TF represses one enhancer to maintain a subset of high-risk leukemias: 🧵👇 www.biorxiv.org/content/10.1...
